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Doctor insights on: Bence Jones Protein

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Is bence jones protein different from regular protein in urine?

Is bence jones protein different from regular protein in urine?

Yes: Usually, Albumin or a mix of proteins are the stuff in "proteinuria". Bence-jones is immunoglobulin light chains and is much more worrisome. It also often doesn't show on the urine dipsticks that are the usual screen for proteinuria. ...Read more

Protein (Definition)

Proteins are large molecules made up of a smaller class of molecules called amino acids. Proteins play an enormous role in the function of our bodies including enzymes, messengers, replicating dna, ...Read more


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Read that Bence Jones Protein can sometimes appear in 24 hr urine and be missed/normal in serum Free Light Chain Assay? Normal SPEP but no UPEP done..

Read that Bence Jones Protein can sometimes appear in 24 hr urine and be missed/normal in serum Free Light Chain Assay? Normal SPEP but no UPEP done..

No consensus: The serum free light chain assay is newer and is supposed to detect free light chains in serum even before they are detectable in urine. The old protocol was with plasma electrophoresis and urine protein immunofixation. It all depends now on the hematologist's confidence level in the new test. ...Read more

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What do you suggest if my mom has plasmacytoma in upper tibia.we tested serum protin electrophoresis,bence-jones protine,cacium,esr.?

What do you suggest if my mom has plasmacytoma in upper tibia.we tested serum protin electrophoresis,bence-jones protine,cacium,esr.?

Seek Oncologist to t: She needs to be treated by an Oncologist. Treatment may be carried out with radiotherapy(if there is no other abnormality away from Tibia) or Chemotherapy if she has any indications of Myeloma cells outside the Tibia lesion. This is a critical decision to be made only by a specialist (Hematologist or Oncologist) ...Read more

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What does bence Jones urine test indicate? What does upep urine indicate?

What does bence Jones urine test indicate? What does upep urine indicate?

Bence-Jones Protien: Detection of Bence Jones protein may be suggestive of multiple myeloma or Waldenström's macroglobulinemia. The proteins are immunoglobulin light chains (paraproteins) and are produced by neoplastic plasma cells. ...Read more

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3 urine test within couple months and blood in my urine my rbc urine level is 1 have had bence jones labs done that also detected some levels in urine?

3 urine test within couple months and blood in my urine my rbc urine level is 1 have had bence jones labs done that also detected some levels in urine?

Bence jones protein: BJ proteins if seen in urine, probably need further evaluation with a hematologist (blood specialist) who will order more tests, usually blood tests. Based on their assessment plus a complete history, interview and physical exam they will be able to tell you if it needs treatment immediately or whether you can continue watching it for awhile. ...Read more

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Rule out light chain myeloma without biopsy or amyloidsis with fat biopsy? Spot urine lambda bence jones, no m spike in serum or urine. Next 24hr ufe?

Rule out light chain myeloma without biopsy or amyloidsis with fat biopsy? Spot urine lambda bence jones, no m spike in serum or urine. Next 24hr ufe?

Urine light chains: hello~ thats an impossible question for me to answer here. My brain will overheat if I have to do that in 421 words. Be kind to us. Please go and see an Oncologist or a smart general internist and he will answer or even manage your case. Remember that not all light chains in the urine means myeloma. See an expert and have him explain the difference between MGUS and myeloma.thanks ...Read more

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KL FLC chains to rule out light chain myeloma? No m spike in serum or 24-hr urine, but lambda bence jones in spot urine but md didnt order urine ifa?

KL FLC chains to rule out light chain myeloma? No m spike in serum or 24-hr urine, but lambda bence jones in spot urine but md didnt order urine ifa?

Does not add up: How do you know it was lambda bence jones in urine without a urine IFA? This issue is not suitable for this forum as a diagnosis of myeloma requires results of other tests as well, e.g., bone X-ray, bone marrow examination, serum calcium and beta 2 microglobulin levels etc. It would be prudent to discuss the matter with a hematologist. ...Read more

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Hey um using isopure protein n pre work out n bcca is that right for my body?

Hey um using isopure protein n pre work out n bcca is that right for my body?

If taken correctly: In the realm of sports supplementation, protein powder and BCAAs are among the safest. Just take as directed on the packaging. Hope this helps. ...Read more

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I take proper diet ie proteins and all but when i masturbate i start looking so thin n ugly please help me?

I take proper diet ie proteins and all but when i masturbate i start looking so thin n ugly please help me?

Masturbation: Normal: I have absolutely no idea what you are really asking. There is no connection between the normal and natural sexual activity of masturbation and how fat or thin you are. If you are having guilt or anxiety or shame for masturbation then please no there is no medical reason not to masturbate. Every man you know masturbates or has masturbated. This is a normal part of the human experience. ...Read more