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Doctor insights on: Benadryl Vs Dramamine Motion Sickness

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Will Benadryl (diphenhydramine) work for motion sickness? I am going on a long road trip and I get terrible carsickness. Will it work the same as dramamine?

Will Benadryl (diphenhydramine) work for motion sickness?  I am going on a long road trip and I get terrible carsickness. Will it work the same as dramamine?

Hyoscyamine sl: Hyoscyamine 0125 mg sublingual is a pill with the same pharmacologic action as scopolamine, but you do not have to purchase an expensive patch. It works usually in about 10 minutes after symptoms start. ...Read more

Dr. Geoffrey Rutledge
231 doctors shared insights

Motion Sickness (Definition)

A symptom where one feels sick to your stomach because there is a discrepancy in his visual stimuli and the stimuli perceived by the ...Read more


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If I'm already taking Xanax (alprazolam) do I need Dramamine? Does Xanax (alprazolam) already help with motion sickness?

If I'm already taking Xanax (alprazolam) do I need Dramamine? Does Xanax (alprazolam) already help with motion sickness?

Motion sickness: Benzodiazepines as xanax, (alprazolam) aren't as good as antihistamines like dramamine in controlling motion sickness, but in your case if you were on the drug for some time, it might be the best choice. It is rather not recommended to combine antihistamines of any kind with benzodiazepines except under medical supervision, combination would lead to CNS depression, good luck ...Read more

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Safe to take dramamine (dimenhydrinate) and an acupressure band for motion sickness?

Safe to take dramamine (dimenhydrinate) and an acupressure band for motion sickness?

Yes: Dramamine (dimenhydrinate) is a histamine antagonist designed to counter some ill effects of motion in vehicles to which some persons are prone. One of its major side effects is drowsiness. Before taking dimenhydrinate you should check with your doctor that it does not interact with any other medications you are already on. Accupressure bands have not been proven effective. ...Read more

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Took a Dramamine (dimenhydrinate) hour before flight but still had severe motion sickness as plane ascended. (Descending was better) How do I prevent this next time?

Took a Dramamine (dimenhydrinate) hour before flight but still had severe motion sickness as plane ascended. (Descending was better) How do I prevent this next time?

Motion sickness : Talk to your doctor about the scopolamine patch. That can be worn for 3 days around the time of travel and should work better than OTC Dramamine (dimenhydrinate). ...Read more

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Is dramamine (dimenhydrinate) okay to take for severe motion sickness? I am 5 weeks pregnant

Is dramamine (dimenhydrinate) okay to take for severe motion sickness? I am 5 weeks pregnant

Should be: It is classified as a class b drug for pregnancy which means it should be relatively safe. If at all possible, you should avoid all medications early in pregnancy, the most vulnerable time for the developing fetus. You should consult with your ob/ gyn doctor ideally. ...Read more

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Can I take Bonine and Dramamine together for motion sickness treatment? (The nausea already started)

You shouldn't: Although these are 2 different drugs, taken together they increase the risk of drowsiness and side effects ...Read more

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Is it true that you need to be a certain age to buy dramamine (dimenhydrinate) motion sickness pills?

Is it true that you need to be a certain age to buy dramamine (dimenhydrinate) motion sickness pills?

Dramamine (dimenhydrinate).: With a physicians prescription there should not be a problem. ...Read more

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Promethazine dramamine (dimenhydrinate) domperidone which is most effective for motion sickness. Do they also combat anxiety?

Promethazine dramamine (dimenhydrinate) domperidone which is most effective for motion sickness. Do they also combat anxiety?

They do not combat: Anxiety well. Dramamine (dimenhydrinate) would be my choice for motion sickness. They all have a sedating effect to some degree, but this is a far cry from being an effective antianxiety medication in general. If your anxiety is secondary to your. Motion sickness, then they could be of benefit. Best wishes. ...Read more

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Iv dramamine or IV phenergan (promethazine) for. Motion sickness? Which is better if the person is already actively vomiting

Iv dramamine or IV phenergan (promethazine) for. Motion sickness?  Which is better if the person is already actively vomiting

Hospital: If you are at the hospital then let the hospital decide that. Do not try this yourself as you can risk other complications. Usually though IV Phenergan (promethazine) is used most of the time for nausea whereas dramamine is usually taken 30 minutes before known motion sickness. ...Read more

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I take montelukast & zyrtec in the morning & 2 180mg allegra (fexofenadine) at night for chronic urticara, can I take dramamine also for motion sickness while flying?

I take montelukast & zyrtec in the morning & 2 180mg allegra (fexofenadine) at night for chronic urticara, can I take dramamine also for motion sickness while flying?

MOTION SICKNESS: THat combination should be safe, monitor for excess sedation. In chronic URTICARIA you should also block H2 receptor i.e. ZANTAC (ranitidine) 300mg. Make sure at some point in time you have been screened for H. pylori ...Read more

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My son is scheduled for dental work with sedation tomorrow & has to fast from tonight. Is it safe to give Benadryl (diphenhydramine) in the morning for motion sickness?

My son is scheduled for dental work with sedation tomorrow & has to fast from tonight. Is it safe to give Benadryl (diphenhydramine) in the morning for motion sickness?

Not our decision: If your son is being put to sleep for his treatment, the medication may interact with the general anesthetic. The doctor rendering the treatment must make this decision. Call them. ...Read more

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What would work better for motion sickness once vomiting has started... Iv Benadryl or IV phenergan (promethazine)?

Motion sickness: Both can work all right. Have not seen a lot of patients on i/v Benadryl lately, but has seen Phenergan (promethazine) used more frequently through this route. ...Read more

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I get motion sickness on everything, cars, boats etc. What prevention cocktail can I take? Dramamine (dimenhydrinate) and? I just wish I could get sea legs... Misera

I get motion sickness on everything, cars, boats etc. What prevention cocktail can I take? Dramamine (dimenhydrinate) and? I just wish I could get sea legs... Misera

Motion Sickness: Dear miserable with motion. Here are a couple of ideas. The first is to take ginger. Ginger ale, ginger tea, ginger cooked into food or crystallized ginger. The second is ear acupuncture. Unlike some motion sickness medications — these options don't cause sedation or interact with other medications. Good luck. ...Read more

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What is best for airplane motion sickness prevention? Meclizine or Diphenhydramine?

What is best for airplane motion sickness prevention? Meclizine or Diphenhydramine?

Meclizine: Meclizine will likely work better. Another solution is a patch which needs be worn at least 12 hrs ahead of time. I have also seen success with motion sickness wristband. ...Read more

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I have early symptoms of glaucoma perhaps brought on by long use of antihistamines I am flying next month what can I do about motion sickness?

I have early symptoms of glaucoma perhaps brought on by long use of antihistamines I am flying next month what can I do about motion sickness?

Glaucoma: Most medication that have precautions regarding glaucoma have to do with narrow angle glaucoma. Talk to your ophthalmologist to see what type of glaucoma you have, the doctor can also give you suggestions regarding the motion sickness. ...Read more

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If somone is allergic to all antihistamines, what else can they take for motion sickness?

If somone is allergic to all antihistamines, what else can they take for motion sickness?

Transderm Scop (scopolamine): You can try a scopolamine patch (rx only) which will last for 3 days. I have never heard of anyone allergic to all antihistamines although one may experience similar side effects such as drowsiness and dry mouth. ...Read more

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Motion sickness pills (dimenhydrinate)--safe for ship travel?

Motion sickness pills (dimenhydrinate)--safe for ship travel?

Yes: Dimenhydrinate is a histamine antagonist designed to counter some ill effects of motion in cars and boats to which some persons are prone. One of its major side effects is drowsiness. Before taking dimenhydrinate you should check with your doctor that it does not interact with any other medications you are already on. ...Read more

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Is it safe to take dimenhydrinate (for motion sickness) and pepto bismol (bismuth subsalicylate) together?

Is it safe to take dimenhydrinate (for motion sickness) and pepto bismol (bismuth subsalicylate) together?

Yes.: Pepto is not absorbed by the intestines to any signifcant extent. There should be no issues with the two drugs. ...Read more

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Going to be in a car ride for 12 hours have bad anxiety and motion sickness i have 0.5mg Xanax (alprazolam) from my doctor and dramaine can I take them together?

Depends: The MD who prescribed the would be able to answer this better. Having said that. It depends on how much xanax (alprazolam) you use. Xanax (alprazolam) has a relatively short half-life 6-8hrs. If you have never taken both together I would stick to xanax (alprazolam) alone. Needless to say DO NOT DRIVE! ...Read more

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I am Having some mild test taking anxiety with slight nausea / tummy discomfort, I know that antihistamines are used for motion sickness. Could I try?

I am Having some mild test taking anxiety with slight nausea / tummy discomfort, I know that antihistamines are used for motion sickness. Could I try?

Non-med options: Try learning relaxation techniques, eg. guided meditation or deep breathing (see YouTube). They lower heart rate & blood pressure, & help with physical & emotional sides of anxiety. The Best if practiced regularly.
Antihistamines best for anxiety (hydroxyzine is FDA approved, Benadryl (diphenhydramine) =same generation) get into the brain. They unfortunately cut off the "stay awake and alert" signal, not good for exams. ...Read more

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I have painful, itchy hives after hydrocodone, but I am allergic to benadryl...will dramamine help?

No: They are basically the same medicine so you could have an allergy to Dramamine as well. You can use a medication such as Allergra or Claritin for example. Steroids like prednisone can be used if the hives are quite severe. Good luck ...Read more

Dr. John Chiu
1,049 doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more