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Doctor insights on: Benadryl Vs Claritin

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Benadryl (diphenhydramine) vs. Claritin. Which one is better?

Benadryl (diphenhydramine) vs. Claritin. Which one is better?

Depends on reason: Both are antihistamines, both are effective for allergies. Benadryl (diphenhydramine) may be more potent and work better in some individuals, but causes much more sleepiness and the effects wear off more quickly than with claritin. ...Read more

Dr. John Chiu
1,049 Doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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Claritin versus Benadryl (diphenhydramine) for kids?

Claritin versus Benadryl (diphenhydramine) for kids?

Work differently: Claritin in a non-drowsy antihistamine. It doesn't cause sleepiness, but you need to use it every day for it to work really well. It's lousy for severe allergic reactions because it takes days to be fully effective. Benadryl (diphenhydramine) causes drowsiness and only lasts for six hours, but is great for severe allergic reactions and works very quickly. If you're exposed and need help now, Benadryl (diphenhydramine) is better. ...Read more

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Can I take Claritin with benadryl (diphenhydramine)?

Can I take Claritin with benadryl (diphenhydramine)?

Yes: Antihistamine is safe even with 4x the average daily dose. The major side effects would be dry mouth and drowsiness (the latter much less common if one uses the non-sedating type). I believe reactine is equivalent to Claritin (loratadine) in the us. Short answer- it is ok. ...Read more

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Is Benadryl (diphenhydramine) and Claritin the same?

Is Benadryl (diphenhydramine) and Claritin the same?

No and yes: They are both antihistamines but Benadryl (diphenhydramine) often causes drowsiness but is more effective in drying up the nose. It also has a shorter duration of action than claritin. ...Read more

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Is Claritin comparable to benadryl (diphenhydramine)?

Is Claritin comparable to benadryl (diphenhydramine)?

Both AH: Both act in similar fashion except that Benadryl (diphenhydramine) causes drowsiness and dry mouth in a much higher percentage of people and it works for just a few hours vs claritin's nearly 24 hours duration of action. ...Read more

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Can I take Benadryl (diphenhydramine) after claritin?

Can I take Benadryl (diphenhydramine) after claritin?

2 antihistamines: Even though both Benadryl (diphenhydramine) and Claritin are both antihistamines, there should not be significant interaction or side effects if taken at the usual doses. ...Read more

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Cani take Benadryl (diphenhydramine) with loratadine?

Probably yes.: Many people report their 'daily' non-sedating antihistamine in the am does not provide relief until next am. So, if no concerns for gu/heart/bp/med-conflict issues, then they often take a 'sedating' antihistamine at night for continued symptom relief and 'bonus' of sleep aid effect. ...Read more

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Can you take Benadryl (diphenhydramine) with claritin?

Yes: There is no interaction. Since Claritin (loratadine) does not cause drowsiness side effects should not be a problem. However, if Claritin (loratadine) is not solving the problem, alternatives such as Allegra or zyrtec should be considered. ...Read more

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Can Benadryl (diphenhydramine) be taken with claritin?

Can Benadryl (diphenhydramine) be taken with claritin?

Zyrtec and Benadryl (diphenhydramine): Hello. These two antihistamines taken together will probably cause sedation. As physicians, we often times double up on antihistamines in challenging cases but I usually use non-sedating antihistamines when I do this. There are other medications that may work better than this combination. Check with your doctor for other options. ...Read more

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Does Claritin work better than benadryl (diphenhydramine)?

Not necessarily: Claritin is non-sedating at 10 mg and is a once daily medication. It has an onset of action approximately 30 minutes after taking. Benadryl (diphenhydramine) tends to work more quickly but lasts only 4-6 hours and can be sedating. ...Read more

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Take Claritin with benadryl, (diphenhydramine) is this okay?

Not really: These are both antihistamines. If both are needed then physician guidance should be sought. ...Read more

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Can I take Benadryl (diphenhydramine) after taken a claritin?

Can I take Benadryl (diphenhydramine) after taken a claritin?

Not recommended: Claritin is a slow release, non-sedating antihistamine. Benadryl (diphenhydramine) is a faster onset sedating antihistamine. Taking both will have additive effects and possible adverse effects such as sedation. It is not recommended that you take both of these without the guidance of your doctor. If the Claritin is not adequate for your symptoms, there are many other medications that can be prescribed to help. ...Read more

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Can you take Benadryl (diphenhydramine) while taking claritin?

Yes: There is no interaction. Since Claritin does not cause drowsiness side effects should not be a problem. However, if Claritin is not solving the problem (hives or nasal allergies), alternatives such as Allegra or zyrtec should be considered. ...Read more

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Can Benadryl (diphenhydramine) and Claritin be taken together?

Yes: There is no interaction. Since Claritin (loratadine) does not cause drowsiness side effects should not be a problem. ...Read more

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Can you take Benadryl (diphenhydramine) and Claritin together?

Can you take Benadryl (diphenhydramine) and Claritin together?

Antihistamines: They are both antihistamines, so I wouldn't take them together. They both act similarly, so their effect would be too much together. Wait until one wears off before trying the other, about 24 hours or so. ...Read more

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Which goes to work faster? Claritin or Benadryl (diphenhydramine)

About the same speed: Unless Benadryl (diphenhydramine) is injected, either starts to work between 1-2 hrs. ...Read more

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Took Claritin can I take Benadryl (diphenhydramine) the same day?

Claritin (loratadine) and Benadry: Hello. You can take both. Dedications at the recommended doses on the same day. ...Read more

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Can you Claritin and Benadryl (diphenhydramine) be taken together?

Can you Claritin and Benadryl (diphenhydramine) be taken together?

Yes: Most antihistamines are dosed at levels much below the toxic levels. Claritin was initially tested in drug studies at 4 times the current recommended dose. These same studies found that 10 mg yielded nearly equvalent effects as 40 mg. Since there is not a dramatic dose effect, increasing to higher levels rarely improves nasal symptoms. Benadryl (diphenhydramine) may have drying effects but sedation limits the dose. ...Read more

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What is the similarity of Benadryl (diphenhydramine) and claritin?

Both AH: Both act in similar fashion except that Benadryl (diphenhydramine) causes drowsiness and dry mouth in a much higher percentage of people and it works for just a few hours vs claritin's nearly 24 hours duration of action. ...Read more

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Can I take Benadryl (diphenhydramine) and Claritin at the same time?

Can I take Benadryl (diphenhydramine) and Claritin at the same time?

Yes: Antihistamine is safe even with 4x the average daily dose. The major side effects would be dry mouth and drowsiness (the latter much less common if one uses the non-sedating type). I believe reactine is equivalent to Claritin (loratadine) in the us. Short answer- it is ok. ...Read more

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Is it safe to take loratadine and Benadryl (diphenhydramine) together?

Is it safe to take loratadine and Benadryl (diphenhydramine) together?

Depends: They are both in the same family (antihistamines), but a few people have daytime symptoms so take non-sedating med (like loratadine) and its effect wears off before next day's dose, so take a sedating (/older) antihistamine (like benadryl) at bedtime for continued relief and to aid with sleep. If no heart / urinary / blood pressure issues and no other meds to conflict with, not likely a problem. ...Read more

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What are some differences between Benadryl (diphenhydramine) and claritin?

What are some differences between Benadryl (diphenhydramine) and claritin?

Side-effect profile: Benadryl (diphenhydramine) is one of the first generation anti-histamines which cross the blood-brain barrier and therefore causes sedation. It also has a significant drying effect in many patients. Claritin (loratadine) is a second generation and does not cross into the brain and therefore is considered non-sedating. It is usually less drying as well. ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. Ashraf Abdel Azeem
539 Doctors shared insights

Claritin (Definition)

Claritin is a non-sedating antihistamine which is a kind of antihistamine type drug (common ...Read more