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Doctor insights on: Benadryl Time Release

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How much Benadryl (diphenhydramine) is considered too much?

How much Benadryl (diphenhydramine) is considered too much?

Benadryl (diphenhydramine): Either the recommended amount based on weight through the directions on the box or following your doctors recommendations if the recommended dose they made is higher. ...Read more

Dr. John Chiu
1,047 Doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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Can I take 4 benadryl (diphenhydramine) at one time?

Can I take 4 benadryl (diphenhydramine) at one time?

Not recommended: That is above the usual dose and will likely produce significant sleepiness. Even one might be a problem with driving. Furthermore, it is very unlikely to produce more benefit than the recommended dose (1, at most 2). ...Read more

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What will happen if I take 4 or 5 Benadryl at the same time?

Benadryl overdose: It will cause extreme drowsiness. confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia and possible seizures depending on the dosage. ...Read more

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Is it ok to take 75 mg of Benadryl (diphenhydramine) at one time?

Is it ok to take 75 mg of Benadryl (diphenhydramine) at one time?

Benadryl (diphenhydramine): Unless otherwise advised by your doctor, yes it is. ...Read more

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How many Benadryl (diphenhydramine) pills can I take at one time?

Read label: You can take as many pills as directed by label as often as directed by label. Do not attempt to exceed amount or frequency. Be aware that even over-the-counter medications (and dietary supplements) can interact & even interfere w/prescription medications. So always tell your family physician (and other doctors) everything that you're taking whether prescribed or not. ...Read more

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Can I take two extra strength Benadryl (diphenhydramine) night time?

50 mg total: You can take a total of 50 mg up to every 4 hours. I've never heard of extra strength Benadryl (diphenhydramine) (they do make a 50 mg tablet, but I've always seen it behind the counter at a pharmacy). All the over-the-counter strengths I've ever seen are 25 mg, so you can take 2 of those. ...Read more

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Can you take Benadryl (diphenhydramine) and hydrocodine at the same time?

Can you take Benadryl (diphenhydramine) and hydrocodine at the same time?

Be careful: Benadryl (diphenhydramine) can be used with hydrocodone to decrease itching and nausea that sometimes happens with hydrocodone. Benadryl (diphenhydramine) and hydorocodone, however, are both sedating and together cause additive drowsiness. Also both drugs independently can cause constipation and urinary hesitancy, so taken together these problems also can be worse. Be careful and discuss with your doctor. ...Read more

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What could happen if I took 2 50mg Benadryl (diphenhydramine) pills at the same time?

Grogginess: It's not unusual to need higher doses of antihistamines for itchy rashes such as hives or eczema; even, but because the drug crosses into the brain, central nervous system sedation (grogginess, drowsiness, sleepiness) occurs. Don't drive - your reaction times will be slowed. Avoid alcohol. May get dry mouth, and guys with enlarged prostates will find it harder to go. ...Read more

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I take IV Benadryl (diphenhydramine) through my port off and on. Now I'm taking 7 or 8 bottles at a time of the 50mg/1ml twice a day. I tolerate it well.?

I take IV Benadryl (diphenhydramine) through my port off and on. Now I'm taking 7 or 8 bottles at a time of the 50mg/1ml twice a day. I tolerate it well.?

???: What is the question? Not really sure of your dose of benadryl (diphenhydramine). How much is in a bottle? Any time you have to take seven vials of anything you have to wonder if the dose is correct. ...Read more

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My son has been taking excessive amounts of benadryl, (diphenhydramine) 12-20 pills at a time, to get high. What are the dangers, & long term health effects?

My son has been taking excessive amounts of benadryl, (diphenhydramine) 12-20 pills at a time, to get high. What are the dangers, & long term health effects?

Not good: Generally a safe drug from allergies, and toxicity in usual dosages.
Usually makes people sleep before "high",
but. A bad idea to overdose with anything!, . ...Read more

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Can one's body develop a resistance to Benadryl (diphenhydramine) if one takes it on a daily basis? Will the medicine eventually lose it's effectiveness as time passes?

Can one's body develop a resistance to Benadryl (diphenhydramine) if one takes it on a daily basis? Will the medicine eventually lose it's effectiveness as time passes?

Yes: All antihistamines can lose effectiveness. Most are over the counter now and i'd recommend switching to another family like allegra, claritin, (loratadine) or tavist. ...Read more

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Can you take Benadryl (diphenhydramine) and NyQuil at the same time?

Not best idea: Nyquil has an antihistamine in it already, and benadryl (diphenhydramine) is an antihistamine so you run the risk of overdosing on the antihistamine component. This may cause drowsiness, dryness and can possibly effect respiratory drive. So, not a good idea to take both together. ...Read more

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Benadryl (diphenhydramine) and melatonin safe to take at the same time?

Benadryl (diphenhydramine) and melatonin safe to take at the same time?

Melatonin: Unless otherwise advised by your doctor, yes it is safe. ...Read more

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What will happen if you take three Benadryl (diphenhydramine) liqui gels at the same time?

BENADRYL (diphenhydramine): Each capsule contains 25 mg of Diphenhydramine (benadryl (diphenhydramine)). 75 mg of Benadryl (diphenhydramine) exceeds the normal maximum dose of 50 mg. I would not recommend exceeding 50 mg. The risk is extreme dressiness and perhaps difficulty in functioning. If you are taking other medications that may cause dressiness, the effect will be magnified by also taking 75 mg of benadryl (diphenhydramine). Do not exceed 50 mg for any one dose. ...Read more

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What potential dangers are there from taking Benadryl (diphenhydramine) on a regular/nightly basis for increased nighttime histamine release?

Various: Due to its different properties, side effects from nightly use of Diphenhydramine (benadryl) may include central nervous system depression, tremor, restlessness, impaired memory, hallucinations, cardiac issues (increase heart rate, hypotension), urinary retention, blurred vision. If you require this for continuous use, see your physician for proper evaluation of sleep problems.
Take care. ...Read more

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I just took 10 mg of Benadryl (diphenhydramine) in pill form. Now I am itchy and tingly all over. This is the second time this has happened.?

I just took 10 mg of Benadryl (diphenhydramine) in pill form. Now I am itchy and tingly all over. This is the second time this has happened.?

Avoid Benadryl!: It is probably better to avoid Benadryl (diphenhydramine) if any unpleasant symptoms develop following use of it. There are many alternative antihistamines like Claritin. ...Read more

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Taking zyrtec and Benadryl (diphenhydramine) at the same time okay?

Depends: The combination can cause increased drowsiness; however, if you are taking zyrtec for allergies and you have an allergic reaction, you can take an additional benadryl (diphenhydramine). You should always discuss these interactions with your doctor. ...Read more

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Can I take Benadryl (diphenhydramine) and Claritin at the same time?

Can I take Benadryl (diphenhydramine) and Claritin at the same time?

Yes: Antihistamine is safe even with 4x the average daily dose. The major side effects would be dry mouth and drowsiness (the latter much less common if one uses the non-sedating type). I believe reactine is equivalent to Claritin (loratadine) in the us. Short answer- it is ok. ...Read more

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Could you take dimetapp and Benadryl (diphenhydramine) at the same time?

Probably: But do be aware of the additive effects on drowsiness and dry mouth. ...Read more

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Can you take hydrocodone and Benadryl (diphenhydramine) at the same time?

Yes, but beware.: Beware that the combination may make you very sleepy and cloud your judgement. ...Read more

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Can children have Benadryl (diphenhydramine) and Zofran at the same time?

Benadryl (diphenhydramine) and Zofran: You need to have a very good reason to have the two given together. Both can cause drowsiness and so it is best not to use them together. But you pediatrician would know better as he/she knows the condition of your child if it is necessary to give both together. ...Read more

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Is it ok for child to take Claritin and Benadryl (diphenhydramine) at the same time?

Is it ok for child to take Claritin and Benadryl (diphenhydramine) at the same time?

Yes, but: Yes, but why would they? They are both antihistamines and therefore do the same job. ...Read more

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Is it ok to take prescribed tramadol and Benadryl (diphenhydramine) at the same time?

Yes: Be careful. Both can be sedating. It is however ok to take them together as there is no interaction other than sedation. Do not drive after doing so in order to allow you to monitor any additive sedation. ...Read more

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Can I take zyrtec d and benadryl (diphenhydramine) at the same time?

Better not: Unless you have severe allergic reaction, and only once, otherwise it is not advisable, if you have uncontrollable allergies, better see an allergist, check aaaai. Org or caai. Org for an allergist in your area ...Read more

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Is it safe to take zyrtec and Benadryl (diphenhydramine) at the same time?

No: Both zyrtec and Benadryl (diphenhydramine) belong to the same class of medicines called antihistamines. Taking both at the same time would be taking a double dose of medicine.
Zyrtec is taken once every 12 hours, whereas Benadryl (diphenhydramine) is taken every 4 to 6 hours. ...Read more

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Can you give a child Benadryl (diphenhydramine) and sudafed at the same time?

Can you give a child Benadryl (diphenhydramine) and sudafed at the same time?

Avoid decongestants: Pseudoephedrine (sudafed) can cause irritability and high blood pressure in children but doesn't seem to actually help with congestion until puberty. Sudafed-pe (phenylephrine) has the same issues but typically is very poorly absorbed into the body. These drugs should never be given to children given the potential harm and lack of benefit.
Benadryl should be limited to once a day during a cold. ...Read more

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Can I take alka seltzer plus cold and Benadryl (diphenhydramine) at the same time?

Can I take alka seltzer plus cold and Benadryl (diphenhydramine) at the same time?

Cough medicines: Alka seltzer plus has I believe Acetaminophen and phenylephrine in it which is a decongestant but not an antihistamine. It also has dextromethorphan cough suppressant. Benadryl (diphenhydramine) is an antihistamine. So yes you can take them together of added effect on sinus and nasal congestion. Benadryl (diphenhydramine) can make you sleepy. ...Read more

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Is it possible for me to take Claritin d and Benadryl (diphenhydramine) at the same time?

Is it possible for me to take Claritin d and Benadryl (diphenhydramine) at the same time?

Preferably no: Claritin d should last approximately 24 hours, Benadryl (diphenhydramine) last about 3-4 hours. For treatment of allergic rhinitis or general allergy control most people do not need to take both at the same time. There are some circumstances where both may be taken on the same day but you should be followed and directed by an allergist if you are using so much antihistamines to control your symptoms. ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more