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Doctor insights on: Benadryl Side Effects Of Long Term Use

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Dr. Israr Abbasi
Board Certified, Psychiatry
23 years in practice
77K people helped
1

1
Can Benadryl usage over a long term produce cause similar sexual side effects that ssris produce?

Dr. Israr Abbasi
Board Certified, Psychiatry
23 years in practice
77K people helped
Can Benadryl usage over a long term produce cause similar sexual side effects that ssris produce?

Unlikely : Ssri side effects are very well established where as antihistamine use and sexual side effects are not that well established . I would be more concerned about long term use of antihistamine and the reasons for it . Are you using it for sleep , allergy ? Consult a psychiatrist as theses may be residual sx of depression and treatment may need to be optimized. ...Read more

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Dr. Umesh Patel
Board Certified
37 years in practice
878K people helped
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Dr. Umesh Patel
Board Certified
37 years in practice
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Dr. Michael Rupp
984 doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


Dr. Cyma Khalily
Board Certified, Psychiatry
30 years in practice
1M people helped
2

2
Daily use of Benadryl for sleep aid on a 16 month old. Are there long term side effects?

Dr. Cyma Khalily
Board Certified, Psychiatry
30 years in practice
1M people helped
Daily use of Benadryl for sleep aid on a 16 month old.  Are there long term side effects?

CONTACT PEDIATRICIAN: I think that you should definitely contact your pediatrician about the sleep issues and the use of routine Benadryl in a child. ...Read more

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Dr. Umesh Patel
Board Certified
37 years in practice
878K people helped
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Dr. Umesh Patel
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Dr. Michael Zacharisen
Board Certified, Allergy and Immunology
28 years in practice
4M people helped
3

3
What are long term side effects of diphenhydramine antihistamines and do they lose effectiveness over time? K

Dr. Michael Zacharisen
Board Certified, Allergy and Immunology
28 years in practice
4M people helped
What are long term side effects of diphenhydramine antihistamines and do they lose effectiveness over time?
K

Minimal: Diphenhydramine is the active ingredient in Benadryl and has been around for a very long time. Like most antihistamines, there is not believed to be long term side effects. Losing effectiveness is less well studied, but with ongoing use there could be some development of tolerance or it could be that you are still being exposed to an allergen and that is why symptoms are not controlled. ...Read more

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Dr. John Chiu
Board Certified, Allergy and Immunology
52 years in practice
21M people helped
4

4
How long does Benadryl side effects last?

Dr. John Chiu
Board Certified, Allergy and Immunology
52 years in practice
21M people helped

Less than 12 hrs: Likely from 6 to 12 hrs.

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Dr. Umesh Patel
Board Certified
37 years in practice
878K people helped
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Dr. Lee Perry
Board Certified, Allergy and Immunology
12 years in practice
753K people helped
5

5
Strange side effects of benadryl?

Dr. Lee Perry
Board Certified, Allergy and Immunology
12 years in practice
753K people helped
Strange side effects of benadryl?

Several: The most common side effect of taking too much Benadryl would be excessive drowsiness. Other possible side effects include dizziness, headache, constipation, urinary retention, and heart palpitations. ...Read more

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Dr. Gena Kluwe
Board Certified, Internal Medicine
26 years in practice
576K people helped
6

6
What are side effects of benadryl?

Dr. Gena Kluwe
Board Certified, Internal Medicine
26 years in practice
576K people helped
What are side effects of benadryl?

Most common side: Effects of Diphenhydramine are drowsiness, dry mouth, constipation, blurry vision, thickenened secretions, impaired coordination. There is a big laundry list of the usual anti choline this side effects, but those are the most common. People use it to sleep or for itching most often. ...Read more

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Dr. Lee Perry
Board Certified, Allergy and Immunology
12 years in practice
753K people helped
7

7
What are the side effects of taking too much benadryl?

Dr. Lee Perry
Board Certified, Allergy and Immunology
12 years in practice
753K people helped
What are the side effects of taking too much benadryl?

Several: The most common side effect of taking too much Benadryl would be excessive drowsiness. Other possible side effects include dizziness, headache, constipation, urinary retention, and heart palpitations. ...Read more

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Dr. Ronald Krauser
Board Certified, Rheumatology
47 years in practice
66M people helped
8

8
Can stopping Benadryl after extended use cause side effects?

Dr. Ronald Krauser
Board Certified, Rheumatology
47 years in practice
66M people helped

Not usually: It should not cause any issues.

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Dr. Bahman Omrani
Board Certified, Pain Management
12 years in practice
7M people helped
9

9
What are some side effects of Benadryl on your body?

Dr. Bahman Omrani
Board Certified, Pain Management
12 years in practice
7M people helped

Benadryl can cause : Sedation the nxt day (due to its long1/2-life). Can cause decreased alertness, diminished cognitive function, delirium, dry mouth, blurred vision, urinary retention, constipation, increased intraocular pressure/glaucoma, & many other anticholinergic agent. Ill effects in disease specific states & drug-drug interaction are other concerns. Generally safe when used in moderation for the right purpose. ...Read more

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Dr. Al Hegab
Board Certified, Allergy and Immunology
35 years in practice
2M people helped
10

10
I accidentally took expired Benadryl (6 years old). Should I be looking out for any bad side effects?

Dr. Al Hegab
Board Certified, Allergy and Immunology
35 years in practice
2M people helped

No: Just be careful, side effects depend on many factors, hope you didn't exceed the recommended dosage ...Read more

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Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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Dr. Umesh Patel
Board Certified,
37 years in practice
878K people helped
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