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Doctor insights on: Benadryl Medication

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I've been trying to get pregnant and I am currently taking Zantac (acid reflux) and Benadryl. Could these medications keep me from conceiving? Thanks!

I've been trying to get pregnant and I am currently taking Zantac (acid reflux) and Benadryl. Could these medications keep me from conceiving? Thanks!

Possibly: Ranitidine has not been known to cause any problems with fertility or pregnancy, however diphenhydramine/Benadryl and other antihistamines theoretically can affect the implantation of the egg in the womb by decreasing bloodflow to the uterus. It is still debatable, (and there aren't any good studies on the subject), but it might be good to stop taking benadryl unless you REALLY need it. ...Read more

Dr. John Chiu
1,049 Doctors shared insights

Diphenhydramine (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more


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Can my baby 4 month old take allergy medication as Benadryl (diphenhydramine) or claritin?

Can my baby 4 month old take allergy medication as Benadryl (diphenhydramine) or claritin?

Not likely: At 4 months you should not be giving your child allergy meds. Take him to the pediatrician and see what is going on. ...Read more

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Do anticholinergic medications like Benadryl (diphenhydramine) have a link with mild cognitive impairment?

Do anticholinergic medications like Benadryl (diphenhydramine) have a link with mild cognitive impairment?

No: Unlikely; Benadryl (diphenhydramine) has drowsy effects, but clears out after few hours. Interestingly can cause paradoxical stimulation as a side effect. A chronic mild cognitive impairment could be something else. ...Read more

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Is it okay to mix Benadryl (diphenhydramine) with my other medications?

Is it okay to mix Benadryl (diphenhydramine) with my other medications?

Avoid these: Older antihistamines like Benadryl (diphenhydramine) interact with many drugs. Don't mix it with alcohol, sleeping pills, sedatives, antidepressants, potassium supplements, sodium or potassium phosphate, antipsychotics, MAO inhibitors, symlin (pramlintide), sodium oxybate, Precedex (dexmedetomidine) & abilify (aripiprazole). Loratidine and fexofenadine are as effective & much safer. Discuss this with your doctor. ...Read more

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Can you take Benadryl (diphenhydramine) if you are taking other types of medication for allergies?

Can you take Benadryl (diphenhydramine) if you are taking other types of medication for allergies?

Yes: The limiting factor as to how much antihistamine one can take is generally what the side-effects are. If it makes you too sleepy when combined with other anti-histamines then you should be careful about combining them. ...Read more

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Are there any immediate acting allergy medications I can take other than Benadryl (diphenhydramine)?

Are there any immediate acting allergy medications I can take other than Benadryl (diphenhydramine)?

Several: OTC second generation antihistamines as cetirizine and loratadine, but read the labels and instructions carefully ...Read more

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If Benadryl's plasma clearance is about 9 hours x 5, how long would it remain active to affect the brain and interact with other medications?

If Benadryl's plasma clearance is about 9 hours x 5, how long would it remain active to affect the brain and interact with other medications?

Less than 12 hrs: It may take a long time for a drug to completely clear from the body, the biochemical effect occurs only with a certain blood level. I have yet seen anyone getting drowsy from Benadryl (diphenhydramine) for more than 12 hours. It is the drug level that matters. ...Read more

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Can the any of these medications be causing high blood pressure? Benadryl? Phenagran? And or reglan (metoclopramide)?

Can the any of these medications be causing high blood pressure? Benadryl? Phenagran? And or reglan (metoclopramide)?

All could be: If you look at the possible side effect profile for each of the drugs you mentioned, high blood pressure is listed as a possible side effect for each one. Side effect profiles for drugs are very patient dependent and very hard to predict. Sometimes starting and stopping medications in an orderly fashion can determine if one is causing the undesired side effect. Talk with your doc. ...Read more

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I have red patches all over my body they itch. I went to the hospital and the gave me benadryl, (diphenhydramine) prednisone, &cimetidine these medications did nothing!?

I have red patches all over my body they itch. I went to the hospital and the gave me benadryl, (diphenhydramine) prednisone, &cimetidine these medications did nothing!?

Foolish: ER people treat heart attacks, accidents, emergencies. That's why we call it the emergency room. They are poor at treating "red patches all over". What did they call it? Stop this foolishness and see a dermatologist. When you call, indicate if it is urgent. Is your water safe yet? Do not take Benadryl (diphenhydramine) except bedtime. It is a sleeping pill. Cimetidine is for acid stomach, not for skin. You need a p ...Read more

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Can you take 5 mg of Vicodin and 25 mg of Benadryl together? I weigh 113 pounds and I'm a female. I have an ovarian cyst and I hardly ever take pain medications so I'm a little afraid and my allergies are killing me.

Can you take 5 mg of Vicodin and 25 mg of Benadryl together? I weigh 113 pounds and I'm a female. I have an ovarian cyst and I hardly ever take pain medications so I'm a little afraid and my allergies are killing me.

Nasal steroid?: Whether you can take these medications depend greatly on their adverse effects. Both Benadryl and Vicodin have sedating effect and Vicodin may cause abdominal upset for some people. However if the pain is bad, you may have little choice. If you are referring to nasal congestion, a nasal steroid will likely work better than an antihistamine. ...Read more

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Now off psych medications, like geodon, (ziprasidone) klonopin, ativan, trazodone, that put me to sleep. Am now using Benadryl evernight4 sleep no relaxation or wood

Now off psych medications, like geodon, (ziprasidone) klonopin, ativan, trazodone, that put me to sleep. Am now using Benadryl evernight4 sleep no relaxation or wood

Sleep: Since you have tried many medications for sleep it may be useful to change your lifestyle if you have not already. Daily exercise before 3pm, no caffeine after 3pm, no alcohol in the evening. If these methods do not work consult with a clinical psychologist who can help uncover the difficulties preventing sleep and how to develop better coping skills. My best. ...Read more

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What allergy medication is safe to take if have a history of kidney stones? Allegra, Zyrtec, Benadryl, (diphenhydramine) Claritin?

What allergy medication is safe to take if have a history of kidney stones? Allegra, Zyrtec, Benadryl, (diphenhydramine) Claritin?

All of them: Is unlikely any of these would have an adverse event on your kidney stones. Your physician can clearly help you with this decision ...Read more

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Can some drug you with benadryl (diphenhydramine)?

Can some drug you with benadryl (diphenhydramine)?

Yes: One can be drugged with anything. Benadryl (diphenhydramine) can cause drowsiness, dizziness, confusion, nausea, urinary retention and more if given high doses or to susceptible individuals. ...Read more

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What type of drug is Benadryl (diphenhydramine) and what are its uses?

Benadryl (diphenhydramine): It is a first generation antihistamine. Very powerful but has side effects that many 2nd generation otc antihistamines do not have. Among it uses are for allergies and in otc sleep aides. ...Read more

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I ingested an allergen 5 days ago. I am still having a reaction and Benadryl (diphenhydramine) is the only drug working well. At 190 lbs how much can I take safely?

Unusual: Unless it was a drug, the allergic reaction does not usually lasts this long. As for Benadryl, (diphenhydramine) the dose is more dependent on its side effects than weight. Most people should be able to tolerate up to 50 mg 4x daily (except those ...Read more

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Can a person be truly allergic to benadryl (diphenhydramine)? (not to the die but the drug itself) if so can desensitization work?

Diphenhydramine: Allergy to the active component can occur, very rare though, desensitazation can be performed but why? Desensitazation is resorted to for any any drug if it is the only drug available to treat certain condition and no available alternatives, which isn't the case with diphenhydramine, get a second opinion, take care ...Read more

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Can taking a tablet of xyzal help to blunt an allergic reaction to a drug as fast & effectively as Benadryl (diphenhydramine) would?

Can taking a tablet of xyzal help to blunt an allergic reaction to a drug as fast & effectively as Benadryl (diphenhydramine) would?

Possibly: You don't describe what kind of a reaction and what drug you are asking about. Depending on the medication and reaction, medications other than anti-histamines may be necessary. If you are asking about an itchy rash, odds are that the 2 medications may be equvally effective. ...Read more

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Will benadryl (diphenhydramine) have an effect on a methacholine challenge since its a anticholinergic drug?

Possibly: To get the best indication of bronchial hyper reactivity, you should not take any antihistamines for 3 to 7 days before the challenge. Unless, of course, the point is to see if Benadryl (diphenhydramine) will diminish the reactivity. That's why you need to discuss such questions with the physician who ordered the test. ...Read more

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Which medication is more effective in treating insomnia, promethazine or diphenhydramine? Which one causes more sedative effect?

Which medication is more effective in treating insomnia, promethazine or diphenhydramine? Which one causes more sedative effect?

It depends: The best way to treat insomnia most of the time is with improved sleep hygiene - avoid late day naps or caffeine, only use your bed for sleeping, and ensure you have a proper diet and exercise. Sedation is a side effect of the medicines you mentioned, patients may feel more sedate from either one depending on many things. ...Read more

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Are there any drug interactions? I took 3mg melatonin at 1:30am, Aller-tec at 10:30 am, Lansoprazol at 11:30, and Benadryl (allergic reaction) at 12pm

Nighty night: The worst thing that'lll happen with those meds is that you'll probably get some much needed rest! LOL....I know cuz I've 4 teenagers of my own. At least you've got a good reason to be sleeping with the melatonin and Benadryl (diphenhydramine). That should put you down for a little snooze. Otherwise, you should be good. Do you really need all those drugs? Your pharmacist can also help you with drug interactions ...Read more

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Heard drug allergies r rare, yet I get hives & occas flushing from nsaids, morphine, antiobios, even benadryl! Why is this? Seems unlikely yet happens

Heard drug allergies r rare, yet I get hives & occas flushing from nsaids, morphine, antiobios, even benadryl! Why is this? Seems unlikely yet happens

Unlikely is not ever: Unlikely does not mean impossible. It is very possible to have drug allergies. There can be no rhyme or reason but if you are allergic to these things you cannot use them safely. ...Read more

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Did geodon (ziprasidone) damage my histamine and dopamine receptors? I am taking no psych drugs and do not feel great. Only way to sleep is one Benadryl or 0 rest

No: Geodon (ziprasidone) does not damage histamine or Dopamine receptors nor any other receptors in the central nervous system that we are aware of. I do not know why you were on Geodon (ziprasidone) in the first place, but if you're not feeling well I would recommend that you go back to your physician. It is possible to develop insomnia secondary to your primary psychiatric illness which then continues even if the primary psychiatric illness comes under control. This is called insomnia secondary to a mental disorder. You may get relief from your insomnia with melatonin which is over-the-counter. It is generally taken two hours before the desired time to fall asleep. ...Read more

Benadryl (Definition)

Diphenhydramine is a sedating antihistamine which is a kind of antihistamine type drug (common ...Read more