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Doctor insights on: Bcg Bladder Cancer Treatment Side Effects

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Please explain BCG bladder cancer treatment.?

Please explain BCG bladder cancer treatment.?

Immune system based: Bcg is a weakened bacteria in the family of germs that causes tuberculosis. In bladder cancer, it is believed that interactions of BCG and molecules in the cellular structure of the bladder itself induces an immune-mediated response which can cause superficial cancers of the bladder to regress and can delay or prevent recurrence in many cases. It is usually given weekly for 6 weeks to start. ...Read more

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Dr. Barry Rosen
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Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Is BCG bladder cancer treatment effective or not?

Is BCG bladder cancer treatment effective or not?

Yes: In fact after removal of superficial bladder cancer (not invasive), the standard of care is BCG injections in the bladder for 6 weeks. It is very effective in reducing recurrence. ...Read more

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I was diagnosed with bladder cancer in 1980 and one treatment with BCG 1990, since then one tumor and haven't had tumor since 2000. Do i need a cysto ?

I was diagnosed with bladder cancer in 1980 and one treatment with BCG 1990, since then one tumor and haven't had tumor since 2000. Do i need a cysto ?

Maybe: I think you can avoid a cystoscopy if you do not have any symptoms and your urinalysis is normal. Also, I would base it on your original pathology. If it was a low grade tumor you can hold off. You could do a urine cytology, urine sample looking for abnormal cells, to insure there is no evidence of a more aggressive tumor. ...Read more

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Does BCG treatment for bladder cancer decrease your immune system?

Does BCG treatment for bladder cancer decrease your immune system?

See below : Intravesical BCG used to both treat and prevent recurrence of urothelial bladder cancer. Despite its widespread common usage, its specific mechanism of action poorly understood. BCG is an attenuated form of the bacteria that causes TB (much like a vaccine) that "stimulates" (not weakens) ones immune system in such a way to kill the tumor cells. Pts with weak immune systems have poorer responses. ...Read more

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I failed interferon treatment and BCG treatment for bladder cancer. Is surgery the only option left?

I failed interferon treatment and BCG treatment for bladder cancer. Is surgery the only option left?

Probably best option: If you have failed tretament with BCG and interferon, some patients may reposnd to treatment with valstar (valrubicin). However, depending on the specifics of your bladder cancer, cystectomy and urinary diversion may be your best option. You should discuss this with your urologist. ...Read more

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Is BCG treatment for bladder cancer the same as chemotherapy?

Is BCG treatment for bladder cancer the same as chemotherapy?

No: Bcg is a topical therapy that is essentially a type of immune based therapy applied only to bladder cells. Traditional chemotherapy is given intravenously and thus all body cells are exposed. Some chemotherapy drugs can be given topically like BCG and probably exert their effect via typical cancer cell-killing compared to immune stimulating effects of BCG similarly administered. ...Read more

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If my bladder cancer recurrence after BCG treatment, what is the next option?

Various options: There are a number of factors, including the original pathology, how quickly you recurred, the type of recurrence, etc. In my practice, i will often give a second round of bcg other options include: bcg plus interferon mitomycin c thiotepa valrubicin and of course cystectomy. ...Read more

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For a 70-year-old man who was recently diagnosed with bladder cancer, is BCG a reasonable 1st treatment?

For a 70-year-old man who was recently diagnosed with bladder cancer, is BCG a reasonable 1st treatment?

Maybe: Bcg is a first good step but depends on the biopsy specimen. Bcg is standard treatment for certain types of bladder cancer and if the patient meets those criteria, then it is a good first step. It is not necessarily dependent on age. ...Read more

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BCG treatment to reduce recurrence rate for bladder cancer.I have 2 nd bladder tumor after 5 year of the first.This mean the BCG work or not?

Yes it works: in selective oatients , Intra bladder installation of BCG is very effective in 70% of time for non invasive bladder cancers . Speak to your doctor if you are a candidate or not . ...Read more

Bladder (Definition)

The bladder is a muscular organ in the pelvis that accepts urine from the kidneys, stores the urine at low pressure, & expels the urine during voluntary voiding. Though seemingly a simple reservoir, the bladder is a complex organ intricately connected with the brain and spinal cord with sensory, motor, and autonomic circuits. The muscular layer that contracts during voids ...Read more


Dr. James Lin
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Bcg Bladder (Definition)

It is treatment for bladder cancer in which biologic therapy is combined with bcg as it kills cancer cells. Bcg stands for bacillus calmette guerin solution.It contains weakened bacteria that stimulate the immune system to kill ...Read more