Doctor insights on:
Bcg Bladder Cancer Treatment Side Effects
Immune system based: Bcg is a weakened bacteria in the family of germs that causes tuberculosis. In bladder cancer, it is believed that interactions of BCG and molecules in the cellular structure of the bladder itself induces an immune-mediated response which can cause superficial cancers of the bladder to regress and can delay or prevent recurrence in many cases. It is usually given weekly for 6 weeks to start. ...Read moreSee 1 more doctor answer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
I was diagnosed with bladder cancer in 1980 and one treatment with BCG 1990, since then one tumor and haven't had tumor since 2000. Do i need a cysto ?
Maybe: I think you can avoid a cystoscopy if you do not have any symptoms and your urinalysis is normal. Also, I would base it on your original pathology. If it was a low grade tumor you can hold off. You could do a urine cytology, urine sample looking for abnormal cells, to insure there is no evidence of a more aggressive tumor. ...Read moreSee 1 more doctor answer
See below : Intravesical BCG used to both treat and prevent recurrence of urothelial bladder cancer. Despite its widespread common usage, its specific mechanism of action poorly understood. BCG is an attenuated form of the bacteria that causes TB (much like a vaccine) that "stimulates" (not weakens) ones immune system in such a way to kill the tumor cells. Pts with weak immune systems have poorer responses. ...Read more
I failed interferon treatment and BCG treatment for bladder cancer. Is surgery the only option left?
Probably best option: If you have failed tretament with BCG and interferon, some patients may reposnd to treatment with valstar (valrubicin). However, depending on the specifics of your bladder cancer, cystectomy and urinary diversion may be your best option. You should discuss this with your urologist. ...Read moreSee 1 more doctor answer
No: Bcg is a topical therapy that is essentially a type of immune based therapy applied only to bladder cells. Traditional chemotherapy is given intravenously and thus all body cells are exposed. Some chemotherapy drugs can be given topically like BCG and probably exert their effect via typical cancer cell-killing compared to immune stimulating effects of BCG similarly administered. ...Read moreSee 1 more doctor answer
Various options: There are a number of factors, including the original pathology, how quickly you recurred, the type of recurrence, etc. In my practice, i will often give a second round of bcg other options include: bcg plus interferon mitomycin c thiotepa valrubicin and of course cystectomy. ...Read moreSee 1 more doctor answer
For a 70-year-old man who was recently diagnosed with bladder cancer, is BCG a reasonable 1st treatment?
Not really: Neither one has any benefit but they also do no harm. ...Read more
The bladder is a muscular organ in the pelvis that accepts urine from the kidneys, stores the urine at low pressure, & expels the urine during voluntary voiding. Though seemingly a simple reservoir, the bladder is a complex organ intricately connected with the brain and spinal cord with sensory, motor, and autonomic circuits. The muscular layer that contracts during voids ...Read more
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