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Doctor insights on: Barretts Esopagus

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Does Barrett's oesophagus always cause oesophageal cancer?

Does Barrett's oesophagus always cause oesophageal cancer?

No: Barrett's esophagus is one of the complications of GERD. It is characterized by the replacement of the normal stratified squamous epithelium lining of the esophagus by simple columnar epithelium with goblet cells About 10% of people with chronic symptoms of GERD develop Barrett's esophagus.Patients with Barrett's esophagus do have an increase the risk of developing esophageal adenocarcinoma but the complication is rare with less than 1% of patients developing this particular cancer ...Read more

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Esophagus (Definition)

This is the muscular structure built like a tube that connects your throat to the stomach though which food ...Read more


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What is barrett's esophagus?

What is barrett's esophagus?

Precancerous entity: Barrett's esophagus occurs when metaplastic columnar epithelium (that predisposes to cancer development) replaces the normal tissue of the esophagus. ...Read more

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Whats GERD gastro esophageal reflux disease?

Whats GERD gastro esophageal reflux disease?

GERD defined: Gastroesophageal reflux disease (gerd) involves movement of stomach contents back into your esophagus. Gerd can be "silent" in a substantial # of patients, manifesting with ear/nose/throat & lung problems without heartburn. Heartburn is the common presentation of burning discomfort in your chest with exposure of the esophagus to stomach contents. See earlier healthtap answers for gerd prevention. ...Read more

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Can acid reflux cause esophageal cancer without ever having barretts esophagus?

Can acid reflux cause esophageal cancer without ever having barretts esophagus?

Yes and no: Acid reflux is not clearly a cause of esophageal cancer. But there is an association of reflux (acid and non-acid) to barrett's esophagus/adenocarcinoma of the esophagus. There are other types of esophageal cancers, which may or may not be related to reflux. ...Read more

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Can barretts esophagus lead to cancer of esophagus?

Can barretts esophagus lead to cancer of esophagus?

Yes if untreated: If untreated barrett's ulcer of of esophagus , will tranforms to cancer , as already there is mucosal change ( sqamous metaplasia ) , there is high incidence of malignency and need close observation. ...Read more

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Whats gastric metaplasia?

Whats gastric metaplasia?

Abnormal esophagus: "metaplasia" describes transformation of one tissue type to another. In the lower esophagus, which is lined by squamous epithelium, abnormal exposure to gastric acid juices from reflux can lead the epithelium to convert itself to the kind of glandular lining seen in the stomach. This can be a pre-cancerous change. ...Read more

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Does barrett's esophagus lead to cancer of the esophagus?

Does barrett's esophagus lead to cancer of the esophagus?

It can: Barrett's esophagus increases the risk for developing adenocarcinoma of the esophagus. Patients with barrett's esophagus should be in an endoscopic surveillance program. ...Read more

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Crohns disease, gastroesophageal reflux disease, barrett's esophagus, esophagitis. 2010 had a fundoplication. Why isn't it working anymore?

Crohns disease, gastroesophageal reflux disease, barrett's esophagus, esophagitis.  2010 had a fundoplication.  Why isn't it working anymore?

Many possibilities: See your surgeon and your gastroenterologist. The surgery may have failed, or your symptoms are not related to reflux. If you had barrett's esophagus, all the more reason to be seen by your physicians. ...Read more

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Is barrett's esophagus always something malignant?

No: The vast majority are benign. It's good to check occasionally for little cancers that can develop. ...Read more

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Can acid reflux cause esophageal cancer without the patient ever having barretts esophagus?

Can acid reflux cause esophageal cancer without the patient ever having barretts esophagus?

Possible but unusual: Most likely lower esophageal adenocarcinoma is caused by gerd, which changes the lining of the lower esophagus into that of the stomach (barrett's) which is a precursor for adenocarcinoma. However, one could have squamous cell type without gerd. Best to review with your gastroenterologist. ...Read more

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Esophagitis grade 2 becomes barrettes esophagus?

Esophagitis grade 2 becomes barrettes esophagus?

Possible: To avoid worsening symptoms and possible transformation to Barrett's, I strongly recommend close follow up by a GI specialist for proper treatment and monitoring. ...Read more

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Does marijuana cause barrett's esophagus?

Does marijuana cause barrett's esophagus?

Not known yet: Marijuana does affect the intestinal tract, which includes the esophagus, stomach, and intestines. It is uncertain if marijuana worsens gastroesophageal reflux (the cause of heartburn and barrett's esophagus changes), improves ge reflux, or has no effect on reflux. Those who like marijuana say that marijuana improves reflux symptoms, but there is not good research evidence to back up their claims. ...Read more

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How does GERD lead to barrett's esophagus?

Acidity+cell changes: Your esophagus is not designed to handle acidic secretions. In gerd, the cells in the esophagus are frequently exposed to acidity and become damaged. Over time, the tissue adapts by changing its cells into ones similar to cells in the stomach. This called metaplasia. Because these kinds of cells are abnormal in the esophagus, people with barrett's are at greater risk for esophageal cancer. ...Read more

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Gastro esophageal reflux disease diet recommedations?

Gastro esophageal reflux disease diet recommedations?

Many Possibilities: If this is chronic and not a new problem may need to consider your diet such as things like coffee, smoking, spicy foods, and alcohol intake. Also there can be a chronic infection of the stomach that can cause this called h. Pylori which can be tested for by blood and stool tests. This is treatable with antibiotics. Also try otc meds like Zantac (ranitidine) and Prilosec with maalox. Try changing diet as well. ...Read more

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All the swallow problems, finally an edoscopy. Dr says esophagitis seen, corrugated esophagus esophageal mucosa c/w eosinophilic esophagitis. Help?

All the swallow problems, finally an edoscopy. Dr says esophagitis seen,  corrugated esophagus esophageal mucosa c/w eosinophilic esophagitis. 
Help?

Allergist/GI: See an allergist or a GI doc who is comfortable managing eosinophilic esophagitis (EoE). Often, patients with this condition are managed by both specialties. EoE is often managed with multiple therapies, including food elimination diets, proton pump inhibitors, and swallowed steroids depending on severity and symptoms. Please see doc as this is a chronic, sometimes severe, condition. ...Read more

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What percent of Barrett's esophagus patients have hiatial hernia?

Unclear: Exact numbers depend upon which study is used. However, a meta-analysis of studies done in 2013 did show a strong relationship between hiatal hernia and Barrett's esophagus, with the association being most strong in patients who had longer segments of Barrett's esophagus. This is likely due to more exposure of the esophagus to gastric contents in the presence of a hiatal hernia. ...Read more

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Can barretts metaplasia (no dysplasia) progress directly to adenocarcinoma of esophegus within 4 months of egd scopy?

Can barretts metaplasia (no dysplasia) progress directly to adenocarcinoma of esophegus within 4 months of egd scopy?

Unlikely: Does your question signal that it did happen? Even if biopsies are negative for dysplasia, biopsies are just that, biopsies of a larger lesion. Biopsies always have the chance of having sampling error...Meaning the most severe part of the lesion was not sampled. The risk of sampling error would go up with a larger lesion than was minimally, and not systematically, biopsied. ...Read more

Dr. Michael Samach
243 doctors shared insights

Barrett Esophagus (Definition)

Damage to the lower portion of the tube that connects the ...Read more