Doctor insights on:
Barbiturate Abuse In Children
Barbituric acid: Was discovered in the late 19th century and came into use in the early 20th century for the same uses as it is now - as a sedative. Various congeners were made that were used for anesthesia (thiopental), sleeping pills (nembutal, amytal), as anticonvulsant (phenobarbital). These drugs can be highly toxic and result in overdose frequently, and also cause a terrible physical dependency/addiction. ...Read more
DON'T DO IT: Barbiturates are very dangerous drugs and are no longer used in most of the world for that purpose, and except for phenobarbital for seizure disorders and barbiturates used in anesthesia, should not be used for ANY purpose. They are highly dangerous, cause tremendous addiction/physical dependency and have awful withdrawal syndromes. Treat the insomnia with psychotherapy, and brief use of safer med ...Read more
-barbital: Most of these medications have a generic name ending in -barbital. Secobarbital, phenobarbital, amobarbital are examples. These are nervous system depressants, potentially lethal in overdose, used before surgery, for seizure disorder, but often safer medications are recommended for outpatients before using them due to higher risk (used to be common anxiety/sleep meds). ...Read more
Both are: Sedative hypnotic's and both enhance the activity of inhibitory neurotransmitters in the cns. Both exert action at the GABA receptor complex. Barbiturates also block excitatory neurotransmitter. While the chemical structures are different, the most significant differences are the wider therapeutic window, lower drug tolerance and lower propensity for abuse with the benzodiazepines. ...Read more
Yes, very different: Barbiturates are sedatives with a low "therapeutic index", meaning that a toxic dose isn't much higher than an effective dose. Benzodiazepines are tranquilizers (some sedating, some not) with a higher therapeutic index, i.e., safer. Chemically they are completely different. However, both can be addictive, with tolerance developing with repeated doses. ...Read more
Similar effect: Both are calming agents. However, they have a different mechanism of action. The side effects of barbiturates are more dangerous than those of benzodiazepines. ...Read more
No: Not legally in the usa. I cannot speak for other countries. ...Read more
The typical reason: Is that the urine metabolite was below the "cutoff" levels for the screening which would not then be subjected to confirmation. It is not that barbituates were not in the sample, but that they were below the "positive" quantitative level for confirmation. Barbiturates are not on federally mandated testing so the cutoff level is arbitrarily assigned. ...Read more
None: Nos such otc with barbiturates on it. ...Read more
Few possibilities: There are 3 possible explanations: clerical error (you got the wrong test results), false positive (something legit like Motrin fooled the test), and true positive (you really had barbiturates). Even if you don't use drugs recreationally, some commonly prescribed meds contain barbiturates, eg, migraine meds containing butalbital. ...Read more
Possibly NSAIDS: Motrin and other meds in that class, nsaids "can" infrequently result in a false positive. Some patients may be taking meds. Which contain barbiturate but they are not aware of it, such as "fioricet". Random urine drug tests usually include an initial screening test, sensitive to detect substances but sometimes false pos., these must always be sent for confirmation. ...Read more
Can a person that's had Steven Johnson syndrome from a barbiturate ever receive a barbiturate again like for status epileptus if they need it?
Define StevensJohnso: Stevens-Johnson Syndrome (SJS) has a large variation in severity. That's assuming that the original reaction WAS SJS & not hives. (Did skin fall off?) Also, are you sure it was the barbs that did it? If life-threatening SJS to barbs is confirmed, the only way to reintroduce barbiturates is to desensitize the patient 1st. In status epilepticus (an emergency), you don't have the time to desensitize. ...Read more
R/O TENSION HA: The 4 basic headaches are Tension, Sinus, migraine and cluster. The muscles that originate at the base of the neck insert near the temple. Rest /ice and a darkened room may help. Also a NSAID like Aleve (naproxen) /daypro. Muscle relaxant ie KLONOPIN/ FLEXERIL. Meditation/Yoga/Biofeedback. GF DIET WHOLEAPPROACH. Com You need a full exam an blood work to be through. If symptoms worsen seek medical evaluation ...Read more
Expert opinions? Which is the best barbiturate for inducing sleep and curing eyestrain headaches?
None: Why do you want a barbiturate? There may be safer medications. Consult with your pcp or a sleep medicine physician to find a medication that will meet your needs. ...Read more
No & no: Usually there are minimal 2 no barbiturates used in anesthesia unless it's used early in the induction of anesthesia. They may cause some nausea but the anesthetic agents used 2 keep u asleep & opiates so u don't feel & react to pain during the procedure & paralytic agents r used 2 keep u from moving during the procedure. They r reversed as u awake. Hard 2 incriminate 1 single drug subsets in n/v? ...Read more
Prescribed for what?: There is really only one condition for which a barbiturate can be a drug-of-choice, and that is generalized seizures, for which either Phenobarbital or Primidone (which is metabolized into phenobarbital) can be a first line drug. Barbiturates are mostly complexed with tylenol (acetaminophen) and caffeine in migraine pills like Fioricet etc which I believe is an irrational and dangerous drug. Many better choices. ...Read more
Sedatives: Teh class of barbiturates are sedatives and not used as often today as in the past. Newer agents with fewer side effects and less abuse potential are now available. Most use in now limited to hospitals. ...Read more
Not uncommon: False positives for barbiturates are caused sometimes by totally unrelated drugs and even herbals. It would be important to know which meds you take, and herbals/teas, if any. Common NSAID s like Ibuprofen or Naproxen sometimes can be the reason. Ask your dr if some meds you take can cause it. Best wishes. ...Read more
Barbiturate Abuse (Definition)
A condition where one relies on sedatives. ...Read more
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