Top 20 Doctor insights on: Barbiturate abuse in children

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How is barbiturate abuse suspected?

How is barbiturate abuse suspected?

Barbiturate abuse: Drug screen followed by testing for barbiturate levels in blood. ...Read more

Dr. Heidi Fowler
34 Doctors shared insights

Barbiturate Drug (Definition)

Barbiturates are a kind of ...Read more


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What is the history behind barbiturates? What were they first used for?

What is the history behind barbiturates? What were they first used for?

Barbituric acid: Was discovered in the late 19th century and came into use in the early 20th century for the same uses as it is now - as a sedative. Various congeners were made that were used for anesthesia (thiopental), sleeping pills (nembutal, amytal), as anticonvulsant (phenobarbital). These drugs can be highly toxic and result in overdose frequently, and also cause a terrible physical dependency/addiction. ...Read more

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Does Zopiclone contain barbiturates?

Does Zopiclone contain barbiturates?

Zopiclone: It is a non-benzodiazepine hypnotic. It does not contain barbiturates. ...Read more

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Can you advise me if getting prescribed barbiturates for insomnia?

Can you advise me if getting prescribed barbiturates for insomnia?

DON'T DO IT: Barbiturates are very dangerous drugs and are no longer used in most of the world for that purpose, and except for phenobarbital for seizure disorders and barbiturates used in anesthesia, should not be used for ANY purpose. They are highly dangerous, cause tremendous addiction/physical dependency and have awful withdrawal syndromes. Treat the insomnia with psychotherapy, and brief use of safer med ...Read more

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Could barbiturate use cause tolerance to other sedatives?

Could barbiturate use cause tolerance to other sedatives?

Yes: Barbiturates cause tolerance to other sedatives like valium and other benzodiazapine drugs. ...Read more

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What are some psychiatric medications that are barbiturates?

What are some psychiatric medications that are barbiturates?

-barbital: Most of these medications have a generic name ending in -barbital. Secobarbital, phenobarbital, amobarbital are examples. These are nervous system depressants, potentially lethal in overdose, used before surgery, for seizure disorder, but often safer medications are recommended for outpatients before using them due to higher risk (used to be common anxiety/sleep meds). ...Read more

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What is the difference between barbiturates v benzodiazepines?

Both are: Sedative hypnotic's and both enhance the activity of inhibitory neurotransmitters in the cns. Both exert action at the gaba receptor complex. Barbiturates also block excitatory neurotransmitter. While the chemical structures are different, the most significant differences are the wider therapeutic window, lower drug tolerance and lower propensity for abuse with the benzodiazepines. ...Read more

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Is there a difference between barbiturates and benzodiazepines?

Yes, very different: Barbiturates are sedatives with a low "therapeutic index", meaning that a toxic dose isn't much higher than an effective dose. Benzodiazepines are tranquilizers (some sedating, some not) with a higher therapeutic index, i.e., safer. Chemically they are completely different. However, both can be addictive, with tolerance developing with repeated doses. ...Read more

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What is the difference between benzodiazepines and barbiturates?

What is the difference between benzodiazepines and barbiturates?

Similar effect: Both are calming agents. However, they have a different mechanism of action. The side effects of barbiturates are more dangerous than those of benzodiazepines. ...Read more

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What could cause a false negative on a drug test for barbiturates?

What could cause a false negative on a drug test for barbiturates?

The typical reason: Is that the urine metabolite was below the "cutoff" levels for the screening which would not then be subjected to confirmation. It is not that barbituates were not in the sample, but that they were below the "positive" quantitative level for confirmation. Barbiturates are not on federally mandated testing so the cutoff level is arbitrarily assigned. ...Read more

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Which category do sleeping pills fall under? Are they barbiturates?

Which category do sleeping pills fall under? Are they barbiturates?

Some are.: Most of the medications used today are either in the benzodiazepine class or are antidepressant medications. Some are barbiturates. ...Read more

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How did I test positive for barbiturates? I don't do drugs, and lost my job over this.

How did I test positive for barbiturates? I don't do drugs, and lost my job over this.

Few possibilities: There are 3 possible explanations: clerical error (you got the wrong test results), false positive (something legit like Motrin fooled the test), and true positive (you really had barbiturates). Even if you don't use drugs recreationally, some commonly prescribed meds contain barbiturates, eg, migraine meds containing butalbital. ...Read more

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What is the meaning of barbiturates in a random urine test in a patient not taking barbiturates?

What is the meaning of barbiturates in a random urine test in a patient not taking barbiturates?

Possibly NSAIDS: Motrin and other meds in that class, nsaids "can" infrequently result in a false positive. Some patients may be taking meds. Which contain barbiturate but they are not aware of it, such as "fioricet". Random urine drug tests usually include an initial screening test, sensitive to detect substances but sometimes false pos., these must always be sent for confirmation. ...Read more

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Can a person that's had Steven Johnson syndrome from a barbiturate ever receive a barbiturate again like for status epileptus if they need it?

Can a person that's had Steven Johnson syndrome from a barbiturate ever receive a barbiturate again like for status epileptus if they need it?

Define StevensJohnso: Stevens-Johnson Syndrome (SJS) has a large variation in severity. That's assuming that the original reaction WAS SJS & not hives. (Did skin fall off?) Also, are you sure it was the barbs that did it? If life-threatening SJS to barbs is confirmed, the only way to reintroduce barbiturates is to desensitize the patient 1st. In status epilepticus (an emergency), you don't have the time to desensitize. ...Read more

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What is the best barbiturate for inducing sleep and curing eyestrain headaches?

What is the best barbiturate for inducing sleep and curing eyestrain headaches?

R/O TENSION HA: The 4 basic headaches are Tension, Sinus, migraine and cluster. The muscles that originate at the base of the neck insert near the temple. Rest /ice and a darkened room may help. Also a NSAID like Aleve (naproxen) /daypro. Muscle relaxant ie KLONOPIN/ FLEXERIL. Meditation/Yoga/Biofeedback. GF DIET WHOLEAPPROACH. Com You need a full exam an blood work to be through. If symptoms worsen seek medical evaluation ...Read more

Barbiturate Abuse (Definition)

A condition where one relies on sedatives. ...Read more