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Doctor insights on: Band 23 Positive Foe Lyme

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what is difference between IgM and IgG for western blot for lyme. positive for IgM but not IgG, what does that mean? tks

what is difference between IgM and IgG for western blot for lyme. positive for IgM but not IgG, what does that mean? tks

Recent infection: Hi. IgM is present only with recent infection. After IgM levels fall away, IgG takes over for ongoing and recurrent exposure to antigen. (The antibodies in this picture are IgG's). I'm glad your doc was on the ball. She/he may have saved you a world of hurt by making the diagnosis promptly. Good luck! ...Read more

Dr. Randy Baker
623 doctors shared insights

Lyme Disease (Definition)

Lyme is caused by borrelia burgdorferi. Acute symptoms can include bullseye rash, headaches, joint pain, fever, and flu like sx. Chronic symptoms can include fibromyalgia symptoms, nerve pain in extremities, mood swings, brain fog, heart problems. Lab diagnosis is not very reliable, and sometimes clinical ...Read more


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How can someone test positive for two Lyme-specific bands on western blot and NOT have been exposed to Lyme disease? What is magic about 5 bands?

How can someone test positive for two Lyme-specific bands on western blot and NOT have been exposed to Lyme disease?  What is magic about 5 bands?

Immune complexities: Lyme disease is caused by a certain type of bacteria called a 'spirochete'- they are a whole class actually of bacteria and believe it or not can be found commonly in the mouth or elsewhere in the environment. You have to reach a certain 'threshold' with Lyme testing because there could be some cross-reactivity coming from these other types of bacteria. The immune system is extraordinarily complex ...Read more

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I got a Lyme disease test done.& IgG 66 came positive out of the other 10 bands. What does this mean? Do I have Lyme or had it? Should i worry? Thanks

I got a Lyme disease test done.& IgG 66 came positive out of the other 10 bands. What does this mean? Do I have Lyme or had it? Should i worry? Thanks

Not enough info: This test is not evidence of lyme but also not proof you don't have it! ultimately lyme is a clinical diagnosis. 20-30% of those who have it never have a positive western blot. It's really important that the test include the 31 & 34 bands & most labs don't check it- igenex is the best lab for a thorough test. See a doc who uses igenex as that is someone able to make a proper diagnosis.See comment:. ...Read more

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Wb-band 41 positive, dfm showed spirochetes and gemmas.Syphilis-negative.Can it be Lyme with only band 41 positive?Got inactive demyelination lessions

Possibly- more tests: A 41 band alone could signify lyme but is not enough to make the diagnosis. Unfortunately most labs don't do an adequate WB test- it's crucial to test the highly specific 31 & 34 bands & most labs don't. Ignenex does the best test. See http://www.Ilads.Org/lyme_disease/about_lyme.Html consider the controversial culture from advanced laboratory services: http://www.Medscape.Com/viewarticle/778482. ...Read more

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I tested positive for Lyme disease. I was given the EIA (result 6.1), IgG (10 bands present) and IgM WB (3 bands) Does this mean I've had LD for a whi?

Yes: The presence of IgG usually indicates past infection which might have occurred months or even years ago. The presence of IgM indicates a current or recent infection. ...Read more

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Western blot-positive band 41, ELISA-positive. LLMD says I have Lyme, MD is skeptical. Ok so do I start Lyme treatment or not? I'm torn.....

Western blot-positive band 41, ELISA-positive. LLMD says I have Lyme, MD is skeptical. Ok so do I start Lyme treatment or not? I'm torn.....

NO 41 K is only one: 41 K is very common - you need more band than that. Look at your lab report and discuss it with your physician. Some reports require 3 or 4 bands. ...Read more

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I tested positive for Lyme disease in 6?

I tested positive for Lyme disease in 6?

Need more info: So what is your question? One needs to know your symptoms and which 6 bands were positive. It may or may not have any significance. ...Read more

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I tested positive for Lyme and am on the second week of doxcycline. Is it normal to still be having symptoms?

Yes.: Stay the course. It can take a couple of months for the body's reaction to the microbe to go away. Nobody's totally certain about the natural course of Lyme, or exactly how to understand all the labs. Best wishes. ...Read more

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My test came back with IGM 23 band Present and Abnormal. My DR. says I don't have Lyme. That it is an old Lyme. But I feel like I'm dying everyday.

My test came back with IGM 23 band Present and Abnormal. My DR. says I don't have Lyme. That it is an old Lyme. But I feel like I'm dying everyday.

Not unusual: Whether or not your Lyme disease was treated early or late in is common to have significant late manifestations, commonly musculoskeletal pain. You can feel like you have the worst viral infection ever. You should consult with your family physician and possibly get a referral to an infectious disease specialist. ...Read more