Doctor insights on:
Bactrim And Coumadin Interaction
Increases free drug: Much of Coumadin is bound to protein. Many drugs, including bactrim, (sulfamethoxazole and trimethoprim) dislodge it from protein and increase the free (active) drug in the circulation. This usually results in a sharp spike in the inr and can lead to bleeding. If you must take batrim, you may need to skip a dose or two of coumadin. Discuss with your doctor. ...Read more
Is there a negative interaction between bactrim (sulfamethoxazole and trimethoprim) ds and coumadin?
No interaction known:
I'm not a fan of Coumadin because almost every drug & many foods & herbs interact with it, but there are no known interactions between Coumadin & any vinegars- this doesn't mean there can't be-I saw a report from 1 person saying it increased their INR- so use caution. See http://www. Drugs. Com/food-interactions/warfarin. Low doses of Vitamin K can stabilize INR levels:
http://tinyurl. Com/hw6e2uu ...Read more
My mom is on Coumadin (warfarin) and wants to start the hCG diet. Is there a drug reaction between the two? Not asking about the diet but the interactions only.
Possible!: Hcg has been associated with dvt. This would not be recommended. ...Read more
Switching antibiotics from bactrim to Cipro (cipro (ciprofloxacin)floxacin). Bactrim stopped last night/taken for 5 days. Is it ok to start cipro (ciprofloxacin) today or are there any interactions?
Have a 17-year-old taking Bactrim sulfamethoxazole tmp wondering if there will be any drug interaction if she takes an herbal allergy pill that I got at the health food center that has vitamin A, C, pantothenic acid, calcium, zinc, quercetin, n-acety
Probably OK, but...: I doubt there is any serious potential for an adverse interaction. However, one of the problems with "natural" medicines, herbal products, and nutritional supplements, etc is that their exact contents often are unknown, And even when known, there is little research on interations with other drugs. So hard to be certain -- but probably no problem. ...Read more
Are there any interactions between bactrim (sulfamethoxazole and trimethoprim) and olive leaf extract? Or can I take them simultaneously? Also, Bactrim (sulfamethoxazole and trimethoprim) & garlic extract/monoluarin?
Most important thing: You must know when taking Bactrim (sulfamethoxazole and trimethoprim) is that it can form crystals in your kidneys if you don't hydrate enough. So taking larges amount of filtered water to protect your kidneys is paramount. Olive leaf extract which is the heart of the mediterranean diet should not pose a problem, but it's always good to take your supplements separately from your medications in general. You can take UR supplements. ...Read more
Takn Coumadin (warfarin) hvn't ben able 2eat much lately&have los 8+lbs n 2wks I don't know y. But got INR checked 2day & it was 6.1y? Is this dangerous menstrualonalso
Go see your doctor..: Now! You didn't explain why you're taking Coumadin (warfarin) but we typically aim for inr 2-3 if for blood clot or atrial fibrillation or clotting disorder. We aim for 2.5-3.5 if you have mechanical valve. Inr of 6.1 is way too high. Your Coumadin (warfarin) dose needs to be held/adjusted & inr monitored closely until back into therapeutic range. 8 lb weight loss in 2wks is not normal either. Go see your doctor now! ...Read more
Varies: I love dr. Klein's answer: "the dose that works." he is absolutely right. Certain south-east Asian populations have the genetics he mentioned that makes them require higher doses of Coumadin (warfarin) than others the same weight. Generally, smaller people need less than larger, too, but not always. Diet has a lot to do with dosage need. ...Read more
That is a: Tough one. In general frequent testing is needed to get I right at the outset. After that increased monitoring is needed with change in health status, especially new mess which may interact. ...Read more
Many doses: Coumadin (warfarin) comes in a variety of doses: l mg, 2 mg, 4 mg, 5 mg, etc. Because a person may need to adjust doses from time to time, patients may need to have a variety of tablets on hand so they can make easy adjustments at the recommendation of their doctor or coagulation clinic. Coumadin (warfarin) interacts with a variety of medications and even the food we eat, so it's not uncommon to require fine tuning. ...Read more
Depends: Great question; if you are on the medication longterm most healtcare providers check protimes/inrs every month. In the most recent guidelines, however, some organizations are suggesting that every three months may be just as good. ...Read more
Bleeding.: This medication can cause serious bleeding if it affects your blood clotting proteins too much (shown by unusually high inr lab results). Even if your doctor stops your medication, this risk of bleeding can continue for up to a week. Tell your doctor right away if you have any signs of serious bleeding, including: unusual pain/swelling/discomfort/easy bruising, prolonged bleeding from cuts. ...Read more
Bruising, bleeding: The most common side effects of Coumadin (warfarin) are bruising and bleeding. Coumadin (warfarin) affects other medicines and can make them work more or less well than normal. Coumadin (warfarin) can also increase the side effects caused by other drugs. You have to be careful about what you eat with Coumadin (warfarin) and make sure you aren't getting too much vitamin k in your diet since it can counteract the effectiveness of coumadin, (warfarin). ...Read more
AllegraD / warfarin: I can find no warnings in the epocrates database for either fexfenadine or pseudoephedrine, the two ingredients in Allegra (fexofenadine) d regarding interactions with warfarin (coumadin). But just to be sure, check with your pharmacist and your cardiologist. If you are taking Coumadin for a heart condition, your doctor might prefer you take plain allegra (fexofenadine). The d part, sudafed, is a cardiac stimulant. ...Read more
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