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Doctor insights on: B12 Folate Deficiencies

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Microcytes with iron deficiency and microcytes with b12/folate deficiency i don't drink medicine for stomach acid and my hemoglabin is normal ?

Microcytes with iron deficiency and microcytes with b12/folate deficiency i don't drink medicine for stomach acid and my hemoglabin is normal
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What are you asking?: B12 and folate (folic acid) produce macrocytosis. If someone has told you that you are deficient in all three, but not anemic, or if you are perplexed over some lab results, then at best you have a physician who has communicated poorly and you need to get a second opinion from someone else. ...Read more

Folic Acid (Definition)

Folic acid, AKA folate (folic acid) (vit B9), is recommended for all women wanting to get pregnant -- 0.4mg (400mcg) daily, which is important for preventing birth defects like spina bifida. Women w/ a hx these disorders should take 10x that amt daily -- 4mg (4000mcg) through the 3rd month of pregnancy. It won't affect fertility, chances of conception/twins, or periods. ...Read more


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Looking for information on B12 and folate (folic acid) deficiency in vegetarians?

Looking for information on B12 and folate (folic acid) deficiency in vegetarians?

B12 deficient common: Being vegetarian may reduce risk of folate (folic acid) deficiency, as the best sources of folate (folic acid) are dark leafy greens, lentils, beans, broccoli & asparagus.However, fruits & vegies generally don't contain b12, so vegetarians are at risk of B12 deficiency.Eggs and dairy products do have b12, but even vegetarians who eat those average less than half the rda of b12. B12 supplements are thus advised. See comment:. ...Read more

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Why we treat megaloblastic anemia caused by vitamin B12 deficiency with folates (folic acid)?

Why we treat megaloblastic anemia caused by vitamin B12 deficiency with folates (folic acid)?

We don't: Megaloblastic anemia caused by B12 deficiency is treated with b12. Folate (folic acid) deficiency also causes meg. Anemia. Some with B12 deficiency are also deficient in b12, but if one has low B12 ; isn't deficient in folate (folic acid) there's no need to supplement with it. But it won't hurt to take folate (folic acid);if you're among the 1/3 of people with problems converting Folic Acid to it's active form you should take l-5-mthf. ...Read more

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If a 70 yrs old man lost 10 kg in a yr coz depressed, then do you expect that he will have folic/folate deficiency? He did not test yet, but B12 is ok

Depends on his diet: I'm not surprised B12 is ok as we can store a 2-3 year supply! but folate (folic acid) isn't stored ; must be replenished daily. Whether he's deficient depends on recent intake- it's found in lentils, beans ; greens; if not eating much of those or not taking supps he is likely deficient. If he supplements i would advise he use the active form, l-5-mthf. See http://whfoods.Com/genpage.Php?Tname=nutrient;dbid=63. ...Read more

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Will a folate (folic acid) deficiency lead to a vitamin B12 deficiency?

Will a folate (folic acid) deficiency lead to a vitamin B12 deficiency?

No: Many people on self-imposed restrictive vegetarian diets get both. They have similar effects on the blood and are both very serious health problems. ...Read more

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Is high RBC folate (folic acid) associated with vitamin B12 deficiency?

Not likely: Please consult this site for info in this topic. Folate (folic acid) and B12 are needed for efficient red cell production and other functions, but lack of one does not increase the other. http://www.webmd.com/diet/folic-acid. ...Read more

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What causes B12 deficiency? Blood test-B12=158, B6=2.4, folate=12.5, Homocysteine=12.9. I eat a balanced diet. On 325 of aspirin to prevent more DVTs.

What causes B12 deficiency? Blood test-B12=158, B6=2.4, folate=12.5, Homocysteine=12.9. I eat a balanced diet. On 325 of aspirin to prevent more DVTs.

Malabsorption: B12 is readily available in foods of animal origin (including dairy & eggs) so unless one is vegan you'll get enough via diet unless you can't absorb it; this can be caused by low hydrochloric acid, overgrowth of yeast or bacteria in the small intestines or a hereditary condition called pernicious anemia.Take methylcobalamin orally or by injection. See http://bit.ly/1607TG3 & http://bit.ly/1cBhjvn ...Read more

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Person w/ SCAD deficiency, autism, mood disorder. Acutely became agitated, aggressive. Labs/UA wnl except B12 >1999 pg/mL; Folate (folic acid) >19 .9 ng/mL? toxic?

Person w/ SCAD deficiency, autism, mood disorder. Acutely became agitated, aggressive. Labs/UA wnl except B12 >1999 pg/mL; Folate (folic acid) >19 .9 ng/mL? toxic?

How old are you?: We need to know your age. Please put it in your public profile. We cannot answer questions from minors. Knowing your country or state helps, too. Age, location, and gender, can affect our answer, since some conditions are more likely in different places or in different age groups. Be honest! You expect if of us, & we expect it of you! List any meds you take, & any chronic medical problems, too. ...Read more

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Previous ida. Now high B12 and folate (folic acid) levels. Ferritin result is not back. Significant hair loss and sob? Could high folate (folic acid) mask B12 deficiency? Thx

Previous ida. Now high B12 and folate (folic acid) levels. Ferritin result is not back. Significant hair loss and sob? Could high folate (folic acid) mask B12 deficiency? Thx

Masks anemia only: High folate (folic acid) can mask megaloblastic anemia caused by B12 deficiency but does not affect B12 levels. The high B12 levels you have are proof that you don't have B12 deficiency. I don't know what ida is. Hair loss ; sob can have many causes. It sounds like you are being evaluated for possible causes. ...Read more

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Serum b12> 1999 mma 0.4, homocysteine high 19. No folate (folic acid) or iron deficiency normocytic anemia not responding to procrit. Is this an absorption issue?

Serum b12> 1999 mma 0.4, homocysteine high 19. No folate (folic acid) or iron deficiency normocytic anemia not responding to procrit. Is this an absorption issue?

Anemia: can be caused by blood loss or bone marrow suppression as well. More information is needed ( how long have you had a normal iron, folate (folic acid) and b12 level. What is your reticulocyte count ? ( is your bone marrow producing new RBC's) ? How low is your HCT and has it come up or gone down with B12. Is the RDW elevated ( do you put out large and small RBC's at the same time? Any blood loss ? ...Read more

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I am Folate, B12 and Vit D deficient. What does this all mean?

I am Folate, B12 and Vit D deficient. What does this all mean?

Nutritional : If you are vegan, then this is to be expected and you should be taking supplements. You may have malabsorption and may need to consult a GI specialist. ...Read more

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I am Folate, B12 & Vitamin D Deficient. I am not a vegan. In layman’s terms what does this mean for me?

I am Folate, B12 & Vitamin D Deficient. I am not a vegan. In layman’s terms what does this mean for me?

Vitamin deficient: It means you either do not get enough from your diet and sun exposure ( for vitamin D) or you cannot absorb them, due to a malabsorption syndrome, a typical example being celiac disease among many others. ...Read more

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My vitamin B12 level was 292. Is this too low? I was deficient in folate (folic acid) and my homocysteine level was 13.5.

Folate (folic acid) dieficiency: Would be uncommon in an 18 yo. A B12 level between 200 and 400 can be difficult to interpret. Under 200 clearly low and over 400 likely ok. In between is a grey area. ...Read more

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Homocysteine level was 13.5. I have hypothyroidism which i'm on Synthroid (thyroxine) for. I'm folate deficient and B12 level was 292. Should i supplement?

Yes, but: I would also take b12. Homocysteine has five degredation pathways, two mediated by folate, (folic acid) one by b6, and two by b12. 2500 mcg of B12 is 416 x the mdr and reduces homocysteine more than any nutriceutical if no deficiency exists. ...Read more

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I have been told I need b12 injections and have also been put on folic acid. Do I have a deficiency in both? Or am I anaemic?

I have been told I need b12 injections and have also been put on folic acid. Do I have a deficiency in both? Or am I anaemic?

Vitamin B12: deficiency is much more common that many have realized and is now often tested routinely as part of a check-up or evaluation of suspicious symptoms. Often it is not severe enough to cause anemia but a person can benefit from supplementation/replacement. Your doctor/whoever ordered the test can likely explain more. Stay well:) ...Read more

Vitamin B12 Overdose (Definition)

An overdose occurs when an excessive / dangerous dose of a drug / substance is used. Toxicity would be unlikely with Vitamin B12. Adverse effects from Vit B 12 injections may include: "diarrhea, nausea, headaches, & ...Read more


Dr. Randy Baker
1,066 doctors shared insights

Vitamin B12 (Definition)

Vitamin B12 is a vitamin which is a kind of nutritional agent ...Read more