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Doctor insights on: Azathioprine

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Dr. Jeremy Adler
468 doctors shared insights

Azathioprine (Overview)

Azathioprine is a non-steroidal anti-inflammatory which is a kind of pain medication.


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Are there long term affects to taking azathioprine for a child?

Are there long term affects to taking azathioprine for a child?

Genetic mutation: Azathioprine ( Imuran (azathioprine) ) is apurine antimetabolite, immnosupressive agent used after transplantation, if it is the case it is safer than other drugs. It is also used for other diseases like inflamatory bowel dis, rheumatoid arthritis etc, then alternative medication to be used. It can not be used in pregnancy, it has mutagnic potential , potential to develop maligencies, . ...Read more

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Dr. Jeremy Adler
468 doctors shared insights

Azathioprine (Overview)

Azathioprine is a non-steroidal anti-inflammatory which is a kind of pain medication.


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Has anyone with chrons disease taken azathioprine?

Yes: I prescribe it for many of my patients and it is generally effective and well tolerated. ...Read more

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Why don't more doc use azathioprine vs methotrexate? Is methotrexate more mild?

Why don't more doc use azathioprine vs methotrexate? Is methotrexate more mild?

Not every patient: Unfortunately not every patient is a good candidate and some do not tolerate it. Discuss more with your rheumatologist. ...Read more

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Are imuran (azathioprine) tablets effective?

Quite Effective: Imuran (azathioprine) is usually prescribed as an immune suppressant in transplant patients, for rheumatoid arthritis, crohn's and ulcerative colitis. It has been found to be quite effective in these conditions. ...Read more

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How does azathioprine work after a renal transplantation?

How does azathioprine work after a renal transplantation?

OK, but not great: Azathioprine (aza) was the mainstay of drug therapy from the early 1960's to the early 1980's. It works primarily by preventing t-cells from getting excited, multiplying, and attacking the graft. One-year graft survival using aza was approximately 50% while more modern drugs used today result in 95% survival. ...Read more

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Is azathioprine safe?

Yes but: It is a potent medication with potential side effects and long term risks that should be discussed with your doctor. That being said, it is given for serious disease which, if untreated, have their own complications and issues. As is everything in medicine, it is a risk-benefit ratio to decide on using a particular medication or not. ...Read more

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I am on pentasa (mesalamine) and azathioprine. How to decrease toxicity, side effects?

Get another opinion: First, get help from a functional medicine physician in your area by going to a4m.Com and using doctor locator function to determine why you were told you need these meds and see if fixing the underlying problem or using safer nutritional supplements wouldn't be a better choice rather than being stuck on these meds for a lifetime. No meds - no side effects! ...Read more

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I am taking 100 mg azathioprine; 25 mg prednisone for Crohn's flare. I have constant headache and fatigue. Side effect?

Non specific symptom: Unfortunately, headache and fatigue are non-specific. You are on relatively high doses of azathioprine and prednisone. The Prednisone is a steroid. Side effects include trouble sleeping, nervousness, heartburn. Azathioprine suppresses immune system. Side effects include nausea, vomiting, poor appetite. The crohn's flare alone can cause fatigue and headache, just like any illness. ...Read more

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Does anyone know the side effects of azathioprine?

Bone marrow toxicity: Azathioprine is a non specific immunosuppressive drug that works by blocking the proliferation of activated immune white blood cells (lymphocytes, monocytes, granulocytes, etc.). It can cause too much bone marrow suppression, liver toxicity, hair loss, nausea, vomiting, etc. You should discuss any side effects with your doctor. ...Read more

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If I take too much azathioprine for my transplant, will it harm my liver?

If I take too much azathioprine for my transplant, will it harm my liver?

Too much is never OK: Too much of any medicine may cause toxicity. Azathioprine can cause liver dysfunction in a small number of patients, and when you take this drug it is standard to monitor your liver function tests. Sometimes dose adjustments need to be made. ...Read more

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Is azathioprine safe?

Yes but: It is a potent medication with potential side effects and long term risks that should be discussed with your doctor. That being said, it is given for serious disease which, if untreated, have their own complications and issues. As is everything in medicine, it is a risk-benefit ratio to decide on using a particular medication or not. ...Read more

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What is Imuran (azathioprine)?

Imuran (azathioprine): "Azathioprine (Imuran (azathioprine)) is a drug used to treat swelling and pain in arthritis. The most common diseases treated with Imuran (azathioprine) are dermatomyositis, systemic lupus erythematosus and vasculitis. It belongs to a class of medications called disease-modifying antirheumatic drugs (DMARDs) or immunosuppressants. This class of medicines can decrease joint damage and disability" ...Read more

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What is azathioprine 6-mp used for?

Immunosuppression: It's an immunosuppressive drug.....used to for autoimmune conditions, in organ transplants to avoid rejections, as maintenance drug along with other meds ...Read more

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How does imuran (azathioprine) work?

Reduce WBC: Azathioprin (imuran) lowers the white blood cell (WBC) count. Wbcs are part of the immune system that fight infection, but also cause inflammation of crohn's, colitis, etc. The goal of Imuran (azathioprine) is to lower the WBC enough to stop the inflammation, but not enough to result in serious infections. That is why routine blood work monitoring is important. ...Read more

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Can children use Imuran (azathioprine)?

Yes: It was used in organ transplants....it is still used in many countries.....here we have better drugs....though in selected few cases Imuran (azathioprine) still prescribed ...Read more

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Who should not use Imuran (azathioprine)?

Imuran (azathioprine): "IMURAN (azathioprine) should not be given to patients who have shown hypersensitivity to the drug. IMURAN (azathioprine) should not be used for treating rheumatoid arthritis in pregnant women. Patients with rheumatoid arthritis previously treated with alkylating agents (cyclophosphamide, chlorambucil, melphalan, or others) may have a prohibitive risk of malignancy if treated with IMURAN (azathioprine)." See: ...Read more

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Are imuran (azathioprine) tablets effective?

Quite Effective: Imuran (azathioprine) is usually prescribed as an immune suppressant in transplant patients, for rheumatoid arthritis, crohn's and ulcerative colitis. It has been found to be quite effective in these conditions. ...Read more

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When did the drug azathioprine become available?

Early 1960s: It was there before;however, in particular the transplant community started using it from early 60s ...Read more

Dr. Jeremy Adler
130 doctors shared insights

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Dr. Louis Gallia
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