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Doctor insights on: Avastin Melanoma

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What is a melanoma?

What is a melanoma?

A type of skin cance: Melanoma is a type of skin cancer that arises from the pigmented cells (melanocytes) in the skin. In general, it is more malignant than the other two common skin cancer types (basal cell and squamous cell), but early melanoma has a good prognosis. Look online for the abcde for diagnosing melanoma. If you have a suspicious mole - have it checked out by a deramatologist. It could save your life! ...Read more

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Dr. Mike Bowman
950 Doctors shared insights

Skin Cancer (Definition)

A condition in which some element of your skin--which is one of the most complex organs in the body--degenerates into cancer. The three most common types of skin cancer are: basal cell, squamous cell, and melanoma which occur in that order and degree of aggressiveness. Although heredity plays a major role, sun exposure and tobacco use and ...Read more


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How is melanoma diagnosed?

How is melanoma diagnosed?

Learn your ABCD's: Definitive diagnosis is made by biopsy. Melanomas are screened by the abcd's: a-asymmetry; b-irregular borders; c-different colors; d-diameber >6mm (size of pencil eraser). If you notice a mole with these characteristics, get it checked out asap. If you have a skin lesion which is growing, ulcerating, bleeding, or otherwise changing, get it seen as well for evaluation and possible biopsy. ...Read more

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What exactly is a melanoma?

Cancer of melanocyte: Melanoma is cancer of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. These cells predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can originate in any part of the body that contains melanocytes. ...Read more

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Is melanoma hereditary? How?

Is melanoma hereditary? How?

IN A SENSE: A positive family history of melanoma is a risk factor. So is hair-blonde or red-color and eye-blue or green-color, which of course you inherit. The biggest risk factor, though, is sun exposure. ...Read more

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How often is melanoma 1-2 mm?

How often is melanoma 1-2 mm?

Quite common: Most melanomas in the US are diagnosed when they have thickness of 1mm to 3mm) are diagnosed in about 30% of patients and carry an intermediate prognosis with a risk of recurrence between 15-30%. ...Read more

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Which symptom did you have of melanoma?

Which symptom did you have of melanoma?

Use ABCDE RULE: It's best to see a dermatologist but a good rule of thumb is the abcd guidelines a=asymmetry of lesion b=border is irregular c=colors are multiple and not consistent d=diameter is greater than 6mm e=evolution of lesion with changes and enlargement. ...Read more

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How should you know if you have melanoma?

How should you know if you have melanoma?

Skin cancer: Most skin cancers are the result of excessive sun exposure/tanning. Genetics play a strong role too. Any skin lesion that is changing size, color, shape or an area that does not heal is suspicious for skin cancer and should be evaluated by a dermatologist. ...Read more

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Is there any therepies available for melanoma?

Is there any therepies available for melanoma?

Yes: In addition to the surgery mentioned, there are new drugs for melanoma. One, called ipilumimab, is not chemotherapy. It is an immunologic therapy that was approved for use in 2011. It is the first drug to improve survival in stage IV melanoma, and some patients are alive 5-6 years after diagnosis with stage IV melanoma while on the drug. Have hope! ...Read more

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How effective is Dabrafenib for treating melanoma?

Hopeful but not cure: Patients with a V600 BRAF mutation, approximately 40-60% of melanoma patients! And with metastatic/advanced disease may benefit from Debrafenib. However it is not a cure and it tend to prolong disease free survival rather and is typically used in combination with other treatments for optimal outcomes ...Read more

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What are the chances of survival for someone with melanoma?

What are the chances of survival for someone with melanoma?

Depends on stage: Not all cancers are alike, and neither are different melanomas. The survival from melanoma depends on the stage, which is based tumor thickness, ulceration, mitotic rate, lymph node involvement and presence of distant metastases. ...Read more

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What is "melanoma lymphoma"?

What is "melanoma lymphoma"?

I don't know: Melanoma and lymphoma are two separate tumors. Maybe you are seeing a typo or potentially a differential diagnosis and the confirmed diagnosis isn't clear. I would ask your md what it means. ...Read more

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What is melanoma and is it treatable?

Malignant Melanoma: Is a skin cancer which can be aggressive. It is treatable but best outcome is with early diagnosis (low Clarke's level) and early treatment. ...Read more

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What are the complications involving vulval melanoma?

What are the complications involving vulval melanoma?

Nodal spread: If found early and resected there is a good chance for cure. If the pigmented lesion is within the mucosal region, the lesion may be more aggressive and spread more quickly. On the outer surface of the vulvae as with the inner regions the groin nodes must be checked and one may need a groin dissection. Frequently spread goes internally to hypogastric nodes. ...Read more

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Is melanoma genetic?

Is melanoma genetic?

Sometimes: There are a portion of melanomas that have a genetic inheritance, e.G, the dysplastic nevus syndrome. We are not yet certain about exactly how the inheritance works for this. Other rare inherited conditions also increase the risk of melanoma and other cancers too. Finally, there are a large number of melanomas that have no inherited predispostion as well. ...Read more

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Melanoma and lupus related?

Melanoma and lupus related?

Autoimmune, malignanc: Malignant melanoma is a malignant skin cancer that can metastasize. It is seen in pigmented skin lesions. Lupus is an abnormal body response that forms antibodies that can harm vital organs and skin. ...Read more

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What is metastatic melanoma?

Skin cancer: In its most typical form, melanoma is a cancer that originates in cells of the skin called melanocytes. In some cases melanoma can spread to other organs from the skin. When it spreads, it is called metastatic melanoma. ...Read more

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What is a malignant melanoma?

What is a malignant melanoma?

Skin cancer: In its most typical form, melanoma is a cancer that originates in cells of the skin called melanocytes. In some cases melanoma can spread to other organs from the skin. More rare types of melanoma start in the eyes, colon, mouth, bladder and other organs. ...Read more

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When they do a test for melanoma?

Unclear questions: We all need to watch for pigmented skin lesions. If there is a change in size, shape, nodule formation, bleeding, change in color, the lesion needs to be evaluated by a doctor. Diagnsis requires removal of the lesion and examination of the tissue by a pathologist. ...Read more

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Dr. Travis Kidner
2,627 Doctors shared insights

Melanoma (Definition)

Cancer of the melanocyte cells. Melanocyte cells determine the color of your skin. Although these cells are primarily found in your skin, they can also be found in the bowel ...Read more