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Doctor insights on: Avastin For Radiation Necrosis

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What is life expectancy of 49 yr old male with stage IV adenocarcinoma of lung? Receive chemo/avastin radiation last CT showed significant progression

What is life expectancy of 49 yr old male with stage IV adenocarcinoma of lung? Receive chemo/avastin radiation last CT showed significant progression

Hard to say: Predicting how long someone will live with stage IV lung cancer is always difficult. You said that your disease had progressed. I assume that is on a pet/ct scan. It would depend on how much it's progressed. Unfortunately it may be as little as 8 mos. Or less. It depends on any underlying conditions conditions such as copd. I would strongly advise you to discuss this with your oncologist. ...Read more

Gamma Rays (Definition)

This is light of extremely short wavelengths typically produced either among the stars / in cosmic rays or by radioactive element decay. Gamma rays form the background of normal radiation in which we all live; it is substantially greater than the exposure we get from imaging scans or should get from ...Read more


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49 year old male has stage vi lung adenocarcinoma. No gene mutations receiving chemo and avastin (bevacizumab) received radiation on foot and brain. What prognosis?

49 year old male has stage vi lung adenocarcinoma. No gene mutations receiving chemo and avastin (bevacizumab) received radiation on foot and brain. What prognosis?

It varies according : Patients with stage 4 lung cancer have an average survival of 12 months but there is a wide range from 9 months to 18 months. Some patients can live for 2-5 years but that is rare and only happens if their tumor shows a great response to chemotherapy. ...Read more

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Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis? .

Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis?

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Perhaps: Certain chemo and radiation can cause avn. Certain cancers and disease can as well. It is best to discuss this with your oncologist or internist. ...Read more

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Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis? . .

Possible: Certain therapeutics, although not chemotherapy, that are commonly used in cancer patients can be associated with avascular necrosis (avn). Examples of these agents include: zometa, xgeva (denosumab) and avstin that can be associated with osteonecrosis of the jaw. Dexamethasone and radiation therapy can also cause avn. ...Read more

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Is radiation for a squameous cell cancer tumor behind eye on optic nerve next to brain safe or could it cause necrosis of brain. Do I need proton?

Is radiation for a squameous cell cancer tumor behind eye on optic nerve
 next to brain safe or could it cause necrosis of brain. Do I need proton?

Palliative: Retrobulbar optic nerve involvement with metastatic tumor rare. Squamous malignancies are very few in that area. Chemo and RT given have mostly been palliative. Gamma knife therapy might be better than trying proton beam. With RT and chemo results in general have not been that encouraging. ...Read more

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Can you have surgery while taking Avastin (bevacizumab)?

Can you have surgery while taking Avastin (bevacizumab)?

Avoid it, if it is p: Avastin (bevacizumab) causes interference in wound healing. So it is best to stop Avastin (bevacizumab) if you need to undergo surgery. It takes 4 to 6 weeks for the Avastin (bevacizumab) effects to go away after the last dose used.. Then it is safer to do surgery. Your oncologist as well as your surgeon can/will guide you in this regard, if you have not already been told about it. ...Read more

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Does avastin (bevacizumab) reduce male fertility?

Does avastin (bevacizumab) reduce male fertility?

No (so far): Avastin (bevacizumab) is a monoclonal antibody that inhibits blood vessel growth. It can impair fertility in women, but i don't find any studies that show reduction in male fertility. For the fda prescribing information with all side effects, go here: http://www.Gene.Com/gene/products/information/pdf/avastin-prescribing.Pdf. ...Read more

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How does avastin (bevacizumab) affect male fertility?

How does avastin (bevacizumab) affect male fertility?

It doesn't (so far): Avastin (bevacizumab) is a monoclonal antibody that inhibits blood vessel growth. It can impair fertility in women, but i don't find any studies that show reduction in male fertility. For the fda prescribing information with all side effects, go here: http://www.Gene.Com/gene/products/information/pdf/avastin-prescribing.Pdf. ...Read more

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Do you know are avastin (bevacizumab) and Xeloda the same?

Do you know are avastin (bevacizumab) and Xeloda the same?

Different: Xeloda is oral chemotherapy while Avastin (bevacizumab) is a monoclonal antibody targeting vascular growth factor. Bevacizumab (avastin) is a recombinant humanized monoclonal antibody that blocks angiogenesis by inhibiting vascular endothelial growth factor. It also helps with chemo by allowing entry into tumor microvascular structures while Xeloda helps to inhibit DNA synthesis ...Read more

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Which is more effective: Avastin (bevacizumab) or Erbitux?

Which is more effective: Avastin (bevacizumab)  or Erbitux?

Identical: Data on Bevacizumab or Erbitux in patients with metastatic colorectal cancer, patients who do not have a KRAS 12/13 gene mutation, have nearly identical survival rates. These identical results were seen after chemotherapy, where survival with chemo alone was about 5 months vs. 7-8 months using either bevacizumab (Avastin) or cetuximab (Erbitux). ...Read more

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Can avastin (bevacizumab) cause an increase of tumor markers?

Can avastin (bevacizumab) cause an increase of tumor markers?

Bevasizumab or: Avastin (bevacizumab) vies with vascular endothelial growth factor. It's action interferes with development or growth of blood vessels needed by tumors. Causes incresed blood pressure and bleeding as leading toxicity. No obvious reason that it should influence tumor markers. ...Read more

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What effect does avastin (bevacizumab) have on male fertility?

What effect does avastin (bevacizumab) have on male fertility?

Unsure: Avastin (bevacizumab) has shown to be deterimental to female reporuductive potential with up to 30-35% have serious complications (ovarian failure). To my knowledge there are no studies on men. Any chemotherapy has the potential risk of causing fertility issues in the future. You may want to consider freezing sperm with a sperm bank or your local reproductive endocrinologist. Also talk to your oncologist. ...Read more

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I have a history of atypical meningiomas, 2 of 4 were surgically removed & radiated, being treated now with avastin (bevacizumab).Need feedbk on the effectiveness?

I have a history of atypical meningiomas, 2 of 4  were surgically removed & radiated, being treated now with avastin (bevacizumab).Need feedbk on the effectiveness?

Malignant meningioma: Malignant meningiomas produce high levels of vascular endothelial growth factor (vegf)- this is what supports the use of avastin (bevacizumab).No clear data about the effectiveness of avastin (bevacizumab)-however a phase ii study on this topic is ongoing. At this time, the effectiveness is shown only on case reports as this one, published on clinical journal : http://annonc.Oxfordjournals.Org/content/21/12/2445.Full. D/w md. ...Read more

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How is avastin (bevacizumab) affecting my blood glucose level?

How is avastin (bevacizumab) affecting my blood glucose level?

No direct relation: Avastin (bevacizumab)'s main function is to inhibit blood vessel formation. Due to importance of blood vessel formation in wound healing, it can cause potential complications after surgery. Avastin (bevacizumab) can also increase protein leakage from the kidneys, increase blood pressure, or risk of clots or bleeding. Avastin (bevacizumab) is used in treatment of certain cancers and certain eye conditions. It is an antibody; not chemo. ...Read more

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What are your thoughts on avastin (bevacizumab) for ovarian cancer?

What are your thoughts on  avastin (bevacizumab)  for ovarian cancer?

Get the facts: You need a good relationship with at least two very ethical oncologists. You'll spend a huge amount of your or someone else's money for a treatment that makes the cancer stay smaller but probably doesn't prolong life and puts you at risk for death from massive hemorrhage. In the process, you will be adding to scientific knowledge. Informed consent rules; you decide. ...Read more

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Necrosis (Definition)

Necrosis is the the death of cells and tissue. In dentistry, root canals are often needed when the pulp tissue inside a ...Read more