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Doctor insights on: Avascular Necrosis

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Dr. Pietro Seni
215 doctors shared insights

Avascular Necrosis (Overview)

Also known as osteonecrosis, avascular necrosis is the death of bone from interruption of blood supply. This can result in tiny bone fractures and eventual destruction of the entire bone. It can be caused by trauma, blockage of circulation with lipids in the blood, certain diseases like sickle cell disease, Gaucher, and occasionally after exposure to corticosteroids. Sometimes, there is no known cause.


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How does prednisone cause avascular necrosis?

How does prednisone cause avascular necrosis?

Still unknown: Even though there is this very well-established connection between chronic Prednisone use and avascular necrosis, how this occurs remains unclear. Numerous hypotheses abound. Some argue that increased lipids seen with steroids cause vessels to joints to clog, leading to oxygen starvation & bone death. A more popular view is that vessel (venous) walls undergo thickening, leading to poor blood flow. ...Read more

Dr. Pietro Seni
215 doctors shared insights

Avascular Necrosis (Overview)

Also known as osteonecrosis, avascular necrosis is the death of bone from interruption of blood supply. This can result in tiny bone fractures and eventual destruction of the entire bone. It can be caused by trauma, blockage of circulation with lipids in the blood, certain diseases like sickle cell disease, Gaucher, and occasionally after exposure to corticosteroids. Sometimes, there is no known cause.


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What are the signs of avascular necrosis?

Depends on location: Avn can occur many locations including hip, knee, ankle etc. Symptoms evolve slowly and may include pain and swelling of the affected joint. ...Read more

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Describe the features of avascular necrosis.?

Ischemic death of hi: Thblood supply to the center of the ball of you hip joint stops tje bone dies later iyt collapses and the ball shape of your hip is lost the hip collapses arthritis follows all stages are painful death collapse arthritis treted well with a total hip replacement. ...Read more

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My brother was diagnosed with avascular necrosis. Any tips or suggestions for him?

See an MD: Avascular necrosis is the death of a joint due to disturbance of the blood supply. By far the most common is the hip joint and it mostly occurs as a side effect of long term, high dose steroid but also due to trauma to the joint. This is a serious problem, with significant joint pain and malfunction. Your brother has probably seen an orthopedic surgeon who can advise him about options. ...Read more

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What are the tests for avascular necrosis?

What are the tests for avascular necrosis?

Osteonecrosis: Test for avn plain x-ray of the involved bone or joint and to confirm it the principat test is an mri.Dr seni. ...Read more

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Do steriods from chemo cause avascular necrosis?

Do steriods from chemo cause avascular necrosis?

Possibly but others: Although avascular necrosis can be related to corticosteroids it is important to know that there are other causes of avascular necrosis. There is a decrease in blood flow to the area involved. Although corticosteroids can be associated, it depends on dose and time and thus chemo steroids are less likely to be associated. Other causes: alcohol, joint injury and increased pressure ...Read more

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What does avascular necrosis of lunate mean?

Lacks blood supply: For some reason, your lunate bone has lost its blood supply. See an orthopedic hand and wrist specialist for treatment. ...Read more

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How do you treat avascular necrosis?

How do you treat avascular necrosis?

Surgery, meds: The most common solution is joint replacement surgery, but bisphosphonate medications can be used first to try to slow the progression of bone death. ...Read more

Dr. Charles Glueck
455 doctors shared insights

Osteonecrosis (Definition)

Osteonecrosis is a condition in which part of a person's bone dies due to lack of blood flow to the area. The hip and shoulder are more likely to be affected, but osteonecrosis can also involve the knee, elbow, wrist, or ankle. Trauma to the bone can cause osteonecrosis, often there ...Read more


Necrosis (Definition)

Necrosis is the the death of cells and tissue. In dentistry, root canals are often needed when the pulp tissue inside a ...Read more