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Doctor insights on: Avascular Necrosis

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Dr. Pietro Seni
220 Doctors shared insights

Avascular Necrosis (Overview)

Also known as osteonecrosis, it is the death of bone from interruption of blood supply. This can result in tiny bone fractures and eventual destruction of the entire bone.


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How does prednisone cause avascular necrosis?

How does prednisone cause avascular necrosis?

Still unknown: Even though there is this very well-established connection between chronic Prednisone use and avascular necrosis, how this occurs remains unclear.

Numerous hypotheses abound. Some argue that increased lipids seen with steroids cause vessels to joints to clog, leading to oxygen starvation & bone death. A more popular view is that vessel (venous) walls undergo thickening, leading to poor blood flow. ...Read more

Dr. Pietro Seni
220 Doctors shared insights

Avascular Necrosis (Overview)

Also known as osteonecrosis, it is the death of bone from interruption of blood supply. This can result in tiny bone fractures and eventual destruction of the entire bone.


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What are the signs of avascular necrosis?

Depends on location: Avn can occur many locations including hip, knee, ankle etc. Symptoms evolve slowly and may include pain and swelling of the affected joint. ...Read more

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Describe the features of avascular necrosis.?

Ischemic death of hi: Thblood supply to the center of the ball of you hip joint stops tje bone dies later iyt collapses and the ball shape of your hip is lost the hip collapses arthritis follows all stages are painful death collapse arthritis treted well with a total hip replacement. ...Read more

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My brother was diagnosed with avascular necrosis. Any tips or suggestions for him?

See an MD: Avascular necrosis is the death of a joint due to disturbance of the blood supply. By far the most common is the hip joint and it mostly occurs as a side effect of long term, high dose steroid but also due to trauma to the joint. This is a serious problem, with significant joint pain and malfunction. Your brother has probably seen an orthopedic surgeon who can advise him about options. ...Read more

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What are the tests for avascular necrosis?

What are the tests for avascular necrosis?

Osteonecrosis: Test for avn plain x-ray of the involved bone or joint and to confirm it the principat test is an mri.Dr seni. ...Read more

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Do steriods from chemo cause avascular necrosis?

Do steriods from chemo cause avascular necrosis?

Possibly but others: Although avascular necrosis can be related to corticosteroids it is important to know that there are other causes of avascular necrosis. There is a decrease in blood flow to the area involved. Although corticosteroids can be associated, it depends on dose and time and thus chemo steroids are less likely to be associated. Other causes: alcohol, joint injury and increased pressure ...Read more

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What does avascular necrosis of lunate mean?

Lacks blood supply: For some reason, your lunate bone has lost its blood supply. See an orthopedic hand and wrist specialist for treatment. ...Read more

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How do you treat avascular necrosis?

How do you treat avascular necrosis?

Surgery, meds: The most common solution is joint replacement surgery, but bisphosphonate medications can be used first to try to slow the progression of bone death. ...Read more

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Anyone treated avascular necrosis?

Yes: Ask an orthopedic surgeons. We are the physicians who usually end up treating this condition as it may affect the hip, the knee, the ankle, the shoulder as well as other sites. ...Read more

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Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis? . .

Does chemotherapy cause avascular necrosis? Does having cancer treatments such as chemo or radiation increase my risk of avascular necrosis? . .

Possible: Certain therapeutics, although not chemotherapy, that are commonly used in cancer patients can be associated with avascular necrosis (avn). Examples of these agents include: zometa, xgeva (denosumab) and avstin that can be associated with osteonecrosis of the jaw. Dexamethasone and radiation therapy can also cause avn. ...Read more

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What is the cure for avascular necrosis of hips?

What is the cure for avascular necrosis of hips?

Joint replacement: Bisphosphonates (medications typically used for osteoporosis) can be used as a non-surgical approach, but most people need surgery. ...Read more

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What can I do to prevent or lessen the chance of avascular necrosis?

Options limited: Depends on the location and manner of fracture. Shoulder & hips at highest risk for avascular bone necrosis, so only real prevention is not getting injured to begin with. In some special cases you can take steps to reduce risk. Deep sea divers (due to the bends) and patients on high dose long term corticosteroids are more at risk. Talk to your dr. ...Read more

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Does taking weight gaining capsules/tablets continously for two years or so cause avascular necrosis of hips or other joints? I m having it. Plz say.

Does taking weight gaining capsules/tablets continously for two years or so cause avascular necrosis of hips or other joints? I m having it. Plz say.

Several causes: Whether your medications are contributing depends on what you are taking, and what conditions you are taking them for. Avascular necrosis (avn) can be caused by trauma, by medications such as prednisone, by chronic alcoholism, and by many illnesses such as lupus or sickle cell anemia. Your doctor can help you determine what may have caused the avn. ...Read more

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After having hip pain due to injury, MRI showed "avascular necrosis of the hips bilaterally, right greater than left". Is this curable or permanent?

After having hip pain due to injury, MRI showed "avascular necrosis of the hips bilaterally, right greater than left". Is this curable or permanent?

Permanent: This is commonly associated with long term alcohol use, steroid use, or disuse of hips. Do you meet any of these categories? If not, you need to find out why you have it, including rare genetic causes, infections and medications. You should make sure you get a reason for it at your age. Some early results have been seen with stem cell replacement. Next step is hip replacement if it gets too bad. ...Read more

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I have a displaced talus fracture, treated with orif surgery. Is there anything I can do to prevent avascular necrosis while ankle heals?

Follow post op: Instructions. I would imagine the surgeon performing your orif would of discussed this possibility with you. Make sure you don't walk on the foot earlier than ou are supposed to etc. If your a smoker make sure you don't smoke. ...Read more

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What is avascular necrosis?

Avascular necrosis: Bone is a living tissue that is constantly turning over; this involves tightly regulated systems of bone addition and subtraction. In order to deliver the cells that are responsible there needs to be adequate blood flow. If the blood flow is disrupted significantly, the affected areas can undergo avascular necrosis (avn). Avn can lead to collapse of the area and arthritis if it occurs near joints. ...Read more

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Is avascular necrosis serious?

Yes: Avascular necrosis is bone death due to lack of blood supply. This can occur in joints where the blood supply can be easily disrupted by injury or disease. Joints such as the hip, knee, wrist, elbow or ankle. Some medications such as steroids can increase risk of this problem. Disease which have increased risk include diabetes, sickle cell disease, gout, atherosclerosis. ...Read more

Dr. Charles Glueck
461 Doctors shared insights

Osteonecrosis (Definition)

-death of bone. This is due 2 loss of blood supply 2 a certain bone part. Common after some injuries such as fractured navicular in the wrist, dislocation of the hip. Some R due 2 drugs, especially steroids, also alcoholism, in these cases it's usually ...Read more


Necrosis (Definition)

Necrosis is the the death of cells and tissue. In dentistry, root canals are often needed when the pulp tissue inside a ...Read more