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Doctor insights on: Autologous Stem Cell Transplant Multiple Myeloma

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Dr. Keith Stockerl-Goldstein
952 doctors shared insights

Stem Cell Transplantation (Definition)

A stem cell transplant may be needed if you have a disease that damages the cells in the bone marrow or if your received high doses of chemotherapy or radiation. Depending on the type of transplant, your procedure may be called a bone marrow transplant, a cord blood transplant, or a peripheral blood stem cell transplant. All three use stem cells, which are immature cells that give rise to specific cell types. Stem cell transplants are similar to blood transfusions and generally ...Read more


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Is it reasonable to have second autologous stem cell transplant for myeloma?

Yes: This is a very difficult question today because every situation with myeloma is different. We do not double transplant all myeloma patients like we have done in the past. It is sometimes reasonable if the first was previously successful and donor cells remain. We now have so many treatments for myeloma that sometimes we do an allogeneic transplant or treat with other drugs (velcade, carfilzomab. ...Read more

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Life expectancy of myeloma patients after autologous stem cell transplant?

Myeloma : There are many things that go into predicting life expectancy of somebody with myeloma who has an autologous stem cell transplant. The rough estimate for somebody getting a transplant in first remission is about 6-7 years now. However, this is something your oncologist or transplant doctor can talk to you about with more specific information. ...Read more

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Can stem cell transplants cure multiple myeloma?

Can stem cell transplants cure multiple myeloma?

Remission: Multiple myeloma is treated classically with chemotherapy and autologous stem cell transplantation. Both modalities can put the disease on remission and prolong life substantially. I personally do not offer allogeneic stem cell transplant for multiple myeloma unless on clinical trial or under very stringent circumstances. Multiple myeloma remains an incurable but very treatable disease. ...Read more

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Are stem cell transplants for multiple myeloma effective?

Yes.: Autologous stem cells transplants (from yourself as donor when in near remission) result in improved progression free survival and probably overall survival. Allogeneic transplant (from someone else) is more complex, and many would consider it experimental. Although the procedure may cure the disease, there are significant complications and risks that may offset the benefits. ...Read more

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What is an autologous stem cell transplant and am I a candidate for one?

What is an autologous stem cell transplant and am I a candidate for one?

Means of treatment: In some cases, the best way to treat the disease, especially if it has come back after initial treatment is to use doses of chemotherapy or radiation which is high enough to destroy normal bone marrow cells. To "rescue" these cells, they are stimulated with drugs before high dose therapy that cause very immature cells called stem cells to enter the blood where they can be collected and given back. ...Read more

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I am going to have an autologous stem cell transplant what is my survival rate?

I am going to have an autologous stem cell transplant what is my survival rate?

About 97%: In a standard risk situation only 2-3% of patients die from complications related to the transplant. The intermediate and long term survival is a function of the underlying disease and thus comment is not possible without the entire clinical context. ...Read more

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Is there a centre for autologous stem cell transplantation in mumbai?

Is there a centre for autologous stem cell transplantation in mumbai?

Probably: Asia is amongst the leaders in development of adult stem cell centers and applications. ...Read more

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What is the goal/ predicted outcome of autologous stem cell transplantation studies for ms?

What is the goal/ predicted outcome of autologous stem cell transplantation studies for ms?

Multiple sclerosis : Researchers are optimistic. Yet, no proven efficacy as of yet. Mortality is down to 1-2%. Check following site: http://www.Ncbi.Nlm.Nih.Gov/m/pubmed/18565456/. ...Read more

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Dr. Payam Rafat
113 doctors shared insights

Kahler Disease (Definition)

Kahler disease is also known as Multiple myeloma. I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "multiple" bone lesions (especially in advanced disease). Mm is a cancer of plasma cells [highly specialized b white blood cells (lymphocytes)] that produce antibodies. Sx are crab: hypercalcemia, renal insufficency, anemia, ...Read more


Dr. Mark Ingerman
3 doctors shared insights

Transplant (Definition)

In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to ...Read more