Doctor insights on:
Autoimmune Rheumatic Disease
The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more
Rheumatic disease: In a sense, yes. You get a strep pharyngitis infection that creates millions of antibodies to fight the infection. Some of those antibodies can turn rogue and recognize a component of the heart valves as foreign, leading to an immunologic attack on the heart valves. ...Read moreSee 1 more doctor answer
Are all rheumatic diseases auto immune disease s or is there a difference in the 2. If there different what is the difference clinically?
More than a 100 kind: Over 100 different kinds of arthritis and related diseases (rheumatic diseases) some metabolic, gout and pseudogout. Some genetic (hemochromatosis) many autoimmune, your immune system reacts against part of your body. Most common rheumatoid arthritis. There are autoimmune diseases that do not cause arthritis, ms, penphigus. ...Read more
I had uveitis hla b27 disorder. It flares up once in a year. I have no specific symptoms of rheumatic arthrits. How to rule out sle and auto immune ?
Anklyosing spondy: There is a high likelihood that you have ankylosing spondylitis which correlates with the hlab27 already shown to exist in your immune picture. Uveitis is an accompaniment of this condition and can be quite severe. You should check with a rheumatologist as there are features of anklyosing which should be treated to prevent permanent change. ...Read moreSee 2 more doctor answers
In your experience, what is the most common autoimmune or other condition associated with symptomatic cryofibrinogenemia? Or is cryofibrinogenemia typically the primary disease process?
Could be either: This disease often starts with skin lesions (ulcers, purple spots, decreased blood flow to fingers/toes). It can either be primary or secondary. When secondary, it's related to cancer, infection (hepatitis c and others), collagen vascular diseases, or vasculitis. Your doctor has to keep all these possibilities in mind. As an oncologist I have seen it as the first sign of cancer. ...Read moreSee 1 more doctor answer
ACTH stim: The acth stimulation test is still great. Your physician may be able to assay for antibodies against the adrenal cortex though the test isn't 100%. If you has proven hashiomto's this much increases the likelihood. The real question is do you need to be treated for adrenal insufficiency. Missing this is very serious. Good luck. ...Read more
I have an autoimmune inflammatory condition, my brother has cmt. Is it unusual to see two uncommon diseases in full siblings or could they be related?
Unusual, yes.: Cmt, charcot-marie-tooth disease is an inherited disease causing peripheral neuropathy. The affected gene is on chromosome 17. The only identified immune genes on 17 code for cell surface proteins involved in intrinsic immunity. There might be a link if you have an autoinflammatory disorder. Consider discussing with a genetic counselor. ...Read more
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