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The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more
No: It can be due to an underlying autoimmune disorder, such as lupus or rheumatoid arthritis. In this case, the underlying autoimmune disorder may be hereditary; but the autoimmune hemolytic anemia is not hereditary. It is simply the manifestation of the underlying disorder. There are also several causes of autoimmune hemolytic anemia that are not inherited. ...Read more
Lupus: Lupus is a classic autoimmune disease that attacks cells, tissues and organs . It is a systemic auto immune disease that attacks skin, heart, lungs , liver, kidneys , blood vessels and nervous system. Anti body production by b cells are to dna , sm antigen, histones and other proteins of cell nucleus . Immune complex deposition in surfaces damage blood vessels in kidneys and other organs ...Read moreSee 3 more doctor answers
Clear definition: Immune deficiency means that there is a defect in the immune system, and the person is more susceptible to have infectious diseases and cancer. There are ways to help be free of infections. Autoimmunity is a disorder in which the immune system attacks one or more of our own organs, due to a defect of regulation/tolerance. Treatment is with medications to suppress the immune responses. ...Read moreSee 1 more doctor answer
Polyarteritis causes: The answer to your question is "it may be" an auto-immune disorder. Polyarthritis is most often caused by an auto-immune disorder such as rheumatoid arthritis, amyloidosis, psoriatic arthritis, and lupus erythematosus. In addition, it may also be caused by infection with an alphavirus such as chikungunya virus and ross river virus. Ask your physician for more information in your instance. ...Read more
Hygiene Hypothesis: Environmental factors are essential components of the pathogenesis (IBD) and primarily responsible for its growing incidence around the globe.Smoking and the enteric bacterial flora has the most solid evidence currently available. Smoking increases risk & worsens CD , but has a protective effect in UC. High social, economical, educational or occupational status increase the risk of IBD. ...Read moreSee 3 more doctor answers
No: No fibromyalgia is not an autoimmune disease. Fibromyalgia is a syndrome and not a disease. This means it is a collection of symptoms. The hallmark of fibromyalgia is chronic widespread pain. It is felt to be the result of overactive nerves. There appears to be abnormal processing of pain in the central nervous system. (the brain and the spinal cord). ...Read moreSee 2 more doctor answers
ITP is just what...: It sounds like. It is characterized by bleeding, bruising (purpura) and petechiae that develop because of a low PLT count (aka thrombocytopenia), and where the specific trigger for thrombocytopenia is not known (idiopathic). We do know that in itp, the pt makes antibodies to auto-antigens found on the PLT surface (often pla-1) which mark them for destruction. This makes the PLT count low. ...Read moreSee 1 more doctor answer
Dermatomyositis: Dermatomyositis is an autoimmune disease that affects skin and muscles. Anti body associated with this is anti-jo a/b . Dermatomyositis follows a viral illness or as autoimmune entity . In few patients it is present with cancer. It also affects lungs, heart and esophagus . It also overlaps at times with lupus. Scleroderma and sjogren's . Diagnosis by muscle /skin biopsy. ...Read moreSee 2 more doctor answers
No: They are distinctly separate disorders.Get a more detailed answer ›
Am i less likely to have a heart attack? I have autoimmune itp and i was wondering since my blood has a hard time clotting if i'm less likely.
ITP is prothrombotic: Autoimmune itp is a pro-thrombotic disorder; the chance of abnormal clots is always there. Abnormal blood clots usually tend to happen either in the veins or in the arteries. Watch for deep veins thrombosis first; but you are not protected from a coronary event by your itp ; low platelet count. ...Read more
Can I use the nuvaring birth control with autoimmune itp? Last platelet count a month ago was in normal range.
I'm confused. Will having autoimmune itp put me at a higher risk of blood clots on hormonal birth control? I thought I have a hard time clotting.
It depends on your clinical status: The finding of itp is just the beginning. We need to know what else is associated with the itp. You're correct sometimes there's decreased clotting. But sometimes we see low platelets with clotting disorders such as the antiphospholipid antibody syndrome. This is something you need to clarify with your physician. ...Read more
Yes but this is not: The diagnosis depends on what else is happening. Howver its overall pathology resembles a combination of autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura and not neutropenia.You may have something else. Your physician can have you see a hematologist and check you for other autoimmune diseases like lupus ...Read more
Can you have more then 3 autoimmune diseases at once? Eg: hashimotos itp, celiac? The more you have, are you at a higher risk to acquire even more?
Yes: Yes, it is possible to have more than one autoimmune condition. Certain combinations are more common than others. Having one condition definitely makes it more likely that you could get a 2nd condition, compared to someone without autoimmunity. However the most common number of autoimmune conditions to have is one, followed by two, and progressively fewer people with 3, 4, or more conditions. ...Read more
I have severe ITP and severe autoimmune neutropenia. 20 y/o, always tired, can't keep up w/ university or a job anymore. what are my options?
See hematologist: This is something which requires the care of a hematologist and you do need this consult urgently ...Read more
ITP being an auto-immune disease, would a diet with less vitamin A, C and B6, proteins and probiotics to reduce the immune response be useful?
No: ITP is an autoimmune disease in which platelets are destroyed and maybe even inhibited in production. Depending on the platelet count and clinical findings treatment can range from observation follow-up to multiple drug regimens. Dietary changes other than a well balanced and nutritional diet do not help. ...Read more
ITP: Thrombocytopenia or low platelet level can be caused by so many things such as drugs, platelet consumption by clots, infections, vitamin deficiency, cancer related etc. Your doctor has to rule out all those possibilities and ultimately to do a bone marrow biopsy to eval bone marrow. See your md and discuss further re-diagnosis approach/treatment and other things you need to know re - itp. ...Read moreSee 2 more doctor answers
Symptom: Most of the time itp patients are asymptomatic and the only abnormality they have is the low platelet level on their blood counts. They can have bruising, tiny red dots on the skin, roof of the mouth etc- ( ptechiae) or other type of bleeding such as bleeding in the gum , only if platelet level goes down really low-below 30k or so. ...Read moreSee 2 more doctor answers
In the old days....: The "i" in itp stood for idiopathic, which means we didn't know what was causing the problem. We now know this to be an autoimmune process where antibodies recognize proteins on the surface of platelets and target them for destruction by the reticuloendothelial system. Most cases follow an infection (usually viral), but they can also be the presenting feature of autoimmune disorders or malignancy. ...Read moreSee 1 more doctor answer
Bruising, bleeding: People with itp may be at an increased risk of bruising or bleeding, depending on the platelet count and other factors, such as medications. If needed, itp can be treated with steroids or other medications. In some instances, removing the spleen (splenectomy) may be recommended. If you are to require surgery, the surgeon should be made aware of this condition. ...Read moreSee 1 more doctor answer
Can be, but rare: Most people w/ treated itp can expect to live a normal life span. Platelets help the blood clot, so a person w/ extremely low platelets (due to immune system attack in itp) can have fatal bleeding esp in the brain. However, this happens <1% of the time. Your doctor will monitor your platelets, and there are many treatments for itp such as Prednisone that can help maintain a good platelet count. ...Read moreSee 1 more doctor answer
Good: Most patients are able to recover platelet counts and have a mortality rate similar to the general population. For more details see this link. http://bloodjournal.hematologylibrary.org/content/97/9/2549.long. ...Read more
Autoimmune disease: Idiopathic thrombocytopenic purpura (itp) is an autoimmune disease. In this potentially life-threatening disorder self antibodies directed against platelets result in low levels of platelets in the blood. Platelets are necessary for effective blood clotting. People with itp can die from loss of blood after trauma of from a brain hemorrhage. Death is not a psychosomatic disease. ...Read moreSee 1 more doctor answer
It's very rare, but: Does happen. If ones platelet count fall to low enough, spontaneous bleeding can occur. Head bleeds, for example, can be both spontaneous and life-threatening. That being said, the plts that a person with itp does have tend to be more thrombofenic because they are "younger". This helps to mitigate the consequences of low PLT count. Your dr. Can give you additional info. Good luck. ...Read moreSee 1 more doctor answer
Response rate 20-30%: Recent review in blood in may 2012 looked at several articles and found a 5-year response rate in adults to be around 26%. Meaning these patients had a sustained elevation of their platelet count for 5 years. Initially the response rate is close to 60%. It is given weekly for 4 weeks. So in summary, it works well. Hope this helps. ...Read more