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Doctor insights on: Autoimmune Hepatitis Cirrhosis

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Is autoimmune hepatitis fatal?

Is autoimmune hepatitis fatal?

Can be: If left untreated, autoimmune hepatitis can progress to liver failure. If in liver failure, it will be fatal unless you have a liver transplant. However, you can prevent progression of the disease with medications. ...Read more

Autoimmune (Definition)

The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more


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Could liver function tests reveal autoimmune hepatitis?

Could liver function tests reveal autoimmune hepatitis?

Yes: Liver function tests are often elevated in autoimmune hepatitis. This is a non- specific test. If the liver function tests are elevated additional diagnostic tests will be necessary. The anti smooth muscle antibody is one of the most important in pointing to this diagnosis. Tests for other liver diseases such as hepatitis and primary biliary cirrhosis are usually part of the evaluation. ...Read more

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Can chronic hepatitis b infection cause cirrhosis?

Can chronic hepatitis b infection cause cirrhosis?

Yes: Hepatitis b can lead to cirrhosis and liver cancer. The more inflammation present and the higher the viral load the more likely, one will develop cirrhosis. ...Read more

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Can hepatitis C cause liver failure?

Absolutely: Hepatitis c is the number one reason people need a liver transplant in the us. It is estimated that about a third of people with hepatitis c will eventually develop severe liver damage. But it can take 20 to 40 years for cirrhosis to develop. The most important things to do are to stop drinking alcohol and discuss your need for treatment, taking into account all the new drugs in development. ...Read more

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Can lupus cause non-alcoholic fatty liver?

Can lupus cause non-alcoholic fatty liver?

Autoimmune hepatitis: Lupus is associated with autoimmune hepatitis, not nash (non-alcoholic fatty liver). Nash is commonly see in settings of obesity, excessive alcohol intake, diabetes, high cholesterol. Both entities can occur together when respective risk factors for both exist. ...Read more

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Can hepatitis b cause liver failure?

Can hepatitis b cause liver failure?

Yes: Chronic hepatitis b can cause the liver to develop severe scarring from the longstanding inflammation the virus causes. The scarring, commonly referred to as cirrhosis, can be progressive such that more and more liver function is lost to scarring. Eventually there are too few healthy liver cells to remove toxins from the body and liver failure happens, usually over a period of years. ...Read more

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How are alcoholic liver disease and viral hepatitis different?

How are alcoholic liver disease and viral hepatitis different?

Different causes: One is caused by alcohol and the other is caused by a virus which infects the liver, hepatitis b and c are the most common causes of chronic viral hepatitis. As both of these affect and damage the liver they may have similar symptoms such a jaundice and evenually cirrhosis. The treatment however would be different. Having a viral hepatitis and drinking would speed the progression of the damage. ...Read more

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Is liver cirrhosis curable?

Is liver cirrhosis curable?

No: No, but you stop it from progressing further by eliminating the cause: abstaining from alcohol or treating hepatitis b or c. ...Read more

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Pathophysiology of liver cirrhosis?

Pathophysiology of liver cirrhosis?

See below: Scar tissue in the liver as a result of different kinds of injuries. The significance is related to the chronicity for the injury and especially whether the injury is ongoing. ...Read more

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Fatty liver NASH wilson's disease, tell me more?

Fatty liver NASH wilson's disease, tell me more?

Confusion: Clinically and under the microscope, wilson's (rare) can look treacherously like alcoholic liver disease or non-alcoholic steatohepatitis (nash, very common). In fact, even weighing the copper in the liver can be misleading because the biopsy may be regenerative nodules. A urinary copper check is part of my preferred workup, and consider a genetic check. ...Read more

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Can chronic hepatitis B inactive carrier clear hepatitis infection ?

Possible: For reasons that we do not yet understand a small percentage of hepatitis B carriers do clear the infection. Unless it is cleared hepatitis B carriers can transmit infection through sexual activity and blood exchange. ...Read more

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Is primary biliary cirrhosis hereditary?

Is primary biliary cirrhosis hereditary?

Basically no: There's a pair of genes that carry the ability to develop the disease and these run in families, but it's not inherited like sickle cell, huntington's or some of the other familiar entities. http://www.medicalnewstoday.com/releases/151640.php. ...Read more

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Is hepatitis b infection associated with liver cancer?

Is hepatitis b infection associated with liver cancer?

Yes: Unlike most viral hepatitides, hepatitis b is associated with liver cancer regardless of the presence of cirrhosis. Therefore, blood test (i.e. Alpha-fetoprotein) and imaging study (i.E abdominal ultrasound) are recommended every 6 months beginning at the age of 40. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Does hepatitis b lead to liver cancer?

Dr. Liawaty Ho Dr. Ho
4 doctors agreed:

Yes it can : Yes hepatitis b can lead to a liver cancer. Majority of hepatitis b will be cured and resolved by your immune system- some of them however will continue and go into chronic active phase -where the virus remains active and viable inside your body- and this can lead into further damage to your liver - i.e. Liver cirrhosis and liver cancer. ...Read more

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Which liver function test indicates viral hepatitis?

Which liver function test indicates viral hepatitis?

Hepatitis Panels: Liver function tests are not really used to diagnose viral hepatitis, but elevated ast, alt, ggt, alkaline phos, bili can indicate "something" is wrong and needs evaluation::. Hepatitis panels for anti-bodies, core anti-bodies, and antigens for each of the different types of hepatitis (a, b, c, etc.) are used to indicate whether viral hepatitis is present and the severity/length of the infection. ...Read more

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I have autoimmune hepatitis and cirrhosis what would cause my bellybutton to stick out suddenly?

I have autoimmune hepatitis and cirrhosis what would cause my bellybutton to stick out suddenly?

Ascites: If you are starting to develop ascites, it will cause the belly button to stick out. Ascites is the fluid that builds up in the abdomen associated with cirrhosis and hepatitis. ...Read more

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Can autoimmune hepatitis be passed on?

May be: There are some genetic factor causing autoimmune hepatitis. However, there is not a strong factor. Generally speaking if someone has autoimmune hepatitis children or future generation may or may not get autoimmune hepatitis or any other type of autoimmune diseases. ...Read more

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Autoimmune hepatitis--i never heard of this?

Autoimmune hepatitis--i never heard of this?

Here is a good place: To start learning. http://www.ncbi.nlm.nih.gov/pubmedhealth/pmh0001291/.

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Is autoimmune hepatitis fatal?

Can be: If left untreated, autoimmune hepatitis can progress to liver failure. If in liver failure, it will be fatal unless you have a liver transplant. However, you can prevent progression of the disease with medications. ...Read more

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In autoimmune hepatitis, do lfts ever go down?

Yes: With proper treatment, liver enzymes should normalize. This is the goal of treatment. Occasionally treatment resistant disease can occur and occasionally lfts can remain elevated due to other reasons such as fatty liver, alcohol or medications. ...Read more

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Can I still conceive if I have autoimmune hepatitis?

Yes: You can conceive if you have autoimmune hepatitis. But you need to have close follow-up with your hepatologist and gynecologist, since it is considered high risk pregnancy. Your medication/medications for autoimmune needs to be adjusted or replaced. Certain medication/medications for autoimmune hepatitis may have risk to the baby, although overall risk is low. ...Read more

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What is the best treatment for autoimmune hepatitis?

What is the best treatment for  autoimmune hepatitis?

Prednisone, Azasan (azathioprine): Prednisone with azathioprine in appropriately selected patients, followed by maintainence azathioprine is the treatment for autoimmune hepatitis. ...Read more

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Will autoimmune hepatitis go away after a transplant?

Will autoimmune hepatitis go away after a transplant?

Hopefully: But not always. You will be on powerful immunosuppressive meds that will help but it is important to follow up closely with your liver docs after the surgery. Good luck! ...Read more

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In autoimmune hepatitis, do lfts ever go lower on their own?

In autoimmune hepatitis, do lfts ever go lower on their own?

Yes : Typically we can see different changes in the liver test levels. Usually this is related to therapy but the body is a dynamic biologic factory and periodic changes can occur. ...Read more

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How effective is Budesonide for treating autoimmune hepatitis?

How effective is Budesonide for treating autoimmune hepatitis?

Not effective!: Oral budesonide is poorly absorbed and little will go to your liver. See a rheumatologist or a GI doc! There are better treatment options. This one is off the cuff, unless you have IBD and are having hepatitis do to Crohn's or regional enteritis! ...Read more

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Can you drink occassional alcohol if you have chronic autoimmune hepatitis?

Can you drink occassional alcohol if you have  chronic autoimmune hepatitis?

Sure. But a bad idea: I have to look at your question with a jaundiced eye. You are fighting for your life (or at least the life of your liver) but you are willing to compromise that for a momentary alcoholic high, is that right? Alcohol is toxic to everyone's liver but your liver, because it's sick, is far more vulnerable. You may survive but it will set your recovery back. Your decision but consider the consequences. ...Read more

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How effective are immunosuppressive drugs for treating autoimmune hepatitis?

Each person is diff: Each peson is different. This will depend on the evlauation but some people respond very well while others might not. You need to ask your physician to have you see a liver specialist ...Read more

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I've autoimmune hepatitis, is it possible that the immune system might attack more organs?

Maybe: Generally speaking, people with autoimmune disease can have more than one affecting more than one organ. You need to be followed closely for any new symptoms. ...Read more

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What is autoimmune hepatitis like?

What is autoimmune hepatitis like?

Immune mediated : Autoimmune hepatitis is an immune mediated directed damage to the liver. Some hepatitis is due to viral infections or alcohol. Here this is the body attacking ones own liver hence the term autoimmune. There is more than one type of autoimmune hepatitis and your physician will guide you through this. ...Read more

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What are signs of autoimmune hepatitis?

What are signs of autoimmune hepatitis?

Jaundice & big liver: Skin rashes & spider angioma (see photo) may also be seen. Generally the diagnosis is made when patients present with fatigue, loss of appetite, and weight loss. Examination reveals jaundice. Blood tests reveal liver injury and an autoimmune basis for the injury. Try this website for a more detailed discussion: http://digestive.Niddk.Nih.Gov/ddiseases/pubs/autoimmunehep/ ...Read more

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What can be done for autoimmune hepatitis?

Medication: If you have autoimmune hepatitis, you should see a liver specialist. This disease can be treated with medication that suppress your immune system. If do not get treatment, the disease can progress and cause cirrhosis (extensive scarring of the liver) and eventual liver failure. ...Read more

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Autoimmune hepatitis not responding to medication?

Autoimmune hepatitis not responding to medication?

Change: You may need to change to a different immunosuppressive regimen. If your liver specialist is not very experienced in treating this condition, you could consider getting a second opinion. If nothing works and your liver is failing a transplant could be an option. ...Read more

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Dr. Jay Park
1,187 doctors shared insights

Hepatitis (Definition)

Inflammation of the liver, which can be caused by many things, such as alcohol overuse, excess sugar consumption, viral infections, autoimmune disorders, certain medications, ...Read more


Dr. Abdullah Mubarak
74 doctors shared insights

Autoimmune Hepatitis (Definition)

A disease in which the body's own immune system attacks the liver, causing ...Read more