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Doctor insights on: Autoimmune Hemolytic Anemia Aiha

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Is autoimmune hemolytic anemia hereditary?

Is autoimmune hemolytic anemia hereditary?

No: It can be due to an underlying autoimmune disorder, such as lupus or rheumatoid arthritis. In this case, the underlying autoimmune disorder may be hereditary; but the autoimmune hemolytic anemia is not hereditary. It is simply the manifestation of the underlying disorder. There are also several causes of autoimmune hemolytic anemia that are not inherited. ...Read more

Autoimmune (Definition)

The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more


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How is autoimmune hemolytic anemia diagnosed?

How is autoimmune hemolytic anemia diagnosed?

Bloodwork: An examination may reveal an enlarged spleen. Tests include: direct coombs' test hemoglobin in the urine indirect coombs' test red blood cell count and serum hemoglobin reticulocyte count serum bilirubin levels serum haptoglobin. ...Read more

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Does autoimmune hemolytic anemia affect WBC ?

Does autoimmune hemolytic anemia affect WBC
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Not usually: It depends on the type of autoimmune disorder. In most cases autoimmune hemolytic anemia does not affect WBC. But some autoimmune disorders like SLE may cause hemolytic anemia and neutropenia as well. ...Read more

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How are aplastic and hemolytic anemia differentiated?

How are aplastic and hemolytic anemia differentiated?

See below: Aplastic anemia is when the bone marrow stops producing blood cells. Hemolytic anemia is when red blood cells are being destroyed outside of the bone marrow. ...Read more

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Can Hemorrhagic gastritis precipitate hemolytic anemia.

Can Hemorrhagic gastritis precipitate hemolytic anemia.

Yes: You have to figure out why you are bleeding into your stomach and if there are any other places where you are bleeding and why and if you are making sufficient replacement blood and if not why not. This can be orchestrated, at least at first by your doc, and if things get really messy by a hematologist. Good luck! ...Read more

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What is Coombs negative hemolytic anemia with large granular lymphocytosis. ?

What is Coombs negative hemolytic anemia  with large granular lymphocytosis. ?

Multifactoral: Coombs (-) hemolytic anemia means that you have evidence of hemolysis (RBC fragmentation) that is not immune mediated. Potential causes include medications, artificial valves, microangiopathic causes, and disorders involving the RBC membrane, etc. Large granular lymphocytosis may be reactive or represent a leukemia if absolute levels are 2-20,000 and sustained for >6 mo in your peripheral blood. ...Read more

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Is polychromasia typically associated with microcytic anemia (iron deficient anemia)?

Is polychromasia typically associated with microcytic  anemia (iron deficient anemia)?

Iron deficiency is: Usually hypo chromic. Polychromasia is seen in rapidly changing circumstances like hemolytic anemia. ...Read more

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Can autoimmune cause henoch schonlein purpura?

Yes, it is autommune: Vasculitis below the waste, possible renal involvement. It an autoimmune disease that can be bad. Most patients will have a short lived course. ...Read more

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What is hemolytic anemia?

What is hemolytic anemia?

RBC breakdown: There are many possibilities that would cause RBC breakdown. Antibodies, abnormal RBC membranes (spherocytosis), abnormal hemoglobins (sickle cell, thalassemia), abnormal RBC enzymes. If hemolytic ane is is suspected, many tests may be ordered. ...Read more

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Is malaria and sickle cell anemia related?

Is malaria and sickle cell anemia related?

Sickle cell Trait: can offer some protective value regarding severity of malarial disease. In a person who has sickle-cell trait – the red blood cells are destroyed prematurely before the Plamodium can reproduce. According to one study “Sickle cell trait provides 60% protection against overall mortality. Most of this protection occurs between 2-16 months of life, before the onset of clinical immunity..." ...Read more

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Are ANA and autoimmune hemolytic anemia exactly the same?

Are ANA and autoimmune hemolytic anemia exactly the same?

No: ANA is a test which may be positive for several auto-immune conditions, including autoimmune hemolytics anema. You can have autoimmune hemolytic anemia, with or without positive ana, have to put in context with other tests and the person's condition. ...Read more

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Is auto immune deficiency treatable?

Is auto immune deficiency  treatable?

Absolutely: 1st: are you talking about an immune deficiency or an autoimmune disease? Both can be treated but they require different specialists so you need to know your diagnosis before you decide whom to see. ...Read more

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Is auto immune deficiency treatable?

Is auto immune deficiency treatable?

Clear definition: Immune deficiency means that there is a defect in the immune system, and the person is more susceptible to have infectious diseases and cancer. There are ways to help be free of infections. Autoimmunity is a disorder in which the immune system attacks one or more of our own organs, due to a defect of regulation/tolerance. Treatment is with medications to suppress the immune responses. ...Read more

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Can normochromic or normocytic anemia cause leukemia?

Can normochromic or normocytic anemia cause leukemia?

No: Anemia (normochromic/cytic or not) can be a sign of leukemia (or a variety of other cancerous or non-cancerous conditions). That is it can associated with leukemia. However, it does not cause leukemia. Correlation does not equal causation. ...Read more

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Ferritinin 800, iron 167. And macrocytic anemia. Liver , kidney, wbc, platelets, neutrophil, B12 normal. Why? Is it preleukemia?

Ferritinin 800, iron 167. And macrocytic anemia. Liver , kidney, wbc, platelets, neutrophil, B12 normal. Why? Is it preleukemia?

At least 2 problems: You realize that we can't diagnose you. With the very high serum ferritin and up-there serum iron, assuming the blood was not drawn during an acute illness, you have hemochromatosis until proved otherwise. How anemic you are, whether this is real macrocytosis, what your physical findings and other labs are are best known to your hematology consultation. Hope nobody gave you iron supplements. ...Read more

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Is sickle cell anemia hereditary?

Yes.: it is an autosomal recessive disorder, meaning that both parents must be carriers of the mutation. If they are, the chance of each child being affected is 1 in 4. ...Read more

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How is dapsone induced hemolytic anemia treated?

How is dapsone induced hemolytic anemia treated?

Stopping dapsone: The best way to treat Dapsone related anemia is by discontinuing dapsone. Dapsone causes hemolytic anemia which is dose-dependent and can be stopped only with discontinuing the drug. Usual practice is to use the lowest possible doses of Dapsone and support with vitamin E and folic acid. ...Read more

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What causes sickle cell anemia besides malaria?

What causes sickle cell anemia besides malaria?

Malaria doesnt cause: Sickle cell anemia is a hereditary disease caused by a mutation in the dna coding for hemoglobin. Scientists have long known that sickle cell anemia protects carriers from malaria infections, which could be advantageous in certain parts of the world. Malaria does not cause sickle cell anemia. ...Read more

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Reticulocytes low, pancytopenia, & bone marrow destruction indicates which type of anemia?

Reticulocytes low, pancytopenia, & bone marrow destruction indicates which type of anemia?

Complex problem: It appears that your bone marrow is not making new blood, so you have anemia due to the failure of production. If you have pancytopenia then the problem is much more than anemia alone. Such situation are either due to leukemia or preleukemic conditions like Myelodysplastic syndrome(MDS). You need a blood specialist to help you sort it out and guide you further. ...Read more

Dr. Steven Ginsberg
1,283 doctors shared insights

Anemia (Definition)

Any condition where there is a decrease in the red blood ...Read more


Dr. James Ball
82 doctors shared insights

Anemia, Hemolytic (Definition)

Occurs when red blood cells are destroyed too quickly. ...Read more