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Doctor insights on: Autoimmune Disorder That Progressively Destroys The Thyroid Gland

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Myasthenia gravis is a serious autoimmune disorder in which the body produces antibodies to what?

Myasthenia gravis is a serious autoimmune disorder in which the body produces antibodies to what?

Ach receptor: Mg is a condition in which the body makes antibodies to the muscle receptor for acetyl choline which is the neurotransmitter chemical involved in the transmission of nerve impulses to muscle contraction. These antibodies prevent efficient nerve transmission to muscle and result in weakness and easy fatigue of muscles. ...Read more

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Autoimmune (Definition)

The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more


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Why would autoimmune disorders make the thyroid gland produce excessive thyroxine?

Why would autoimmune disorders make the thyroid gland produce excessive thyroxine?

Antibodies: Some auto-antibodies sit on the thyroid cells and make them over produce thyroid hormone. Other autoantibodies can cause the exact opposite. ...Read more

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Is the risk of thyroid carcinoma increased with diagnosis of hashimoto thyroiditis when multiple thyroid adenomas are present. Tyab 2470?

Is the risk of thyroid carcinoma increased with diagnosis of hashimoto thyroiditis when multiple thyroid adenomas are present. Tyab 2470?

Not if they function: If the adenomas are "cold" or do not function, then they are likely to be malignant. They do not show up on radionuclide scan because they do not function. Otherwise they are unlikely to be malignant. However, since you have many of them, you likely need and should get further workup, like aspiration biopsy, etc., along with treatment for your hashimoto's. ...Read more

Dr. Al Hegab Dr. Hegab
7 doctors agreed:
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Is posterior uveitis, oropharyngeal dysphagia, and gingivostomatitis all related to an autoimmune disorder which is attacking my immune system?

Dr. Al Hegab Dr. Hegab
7 doctors agreed:

Could be: but it's the other way around, it is your immune system that is attacking your tissues in auto immune diseases, whether what you have is related to one of those diseases, is yet to be ruled in. Kindly see a rheumatologist through your primary doctor for evaluation, good luck ...Read more

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What is the significance of radioactive iodine scan in various throid diseases like myxedema, hashimoto's thyroiditis and graves disease?

What is the significance of radioactive iodine scan in various throid diseases like myxedema, hashimoto's thyroiditis and graves disease?

Hot vs. cold nodule: Iodine uptake by thyroid tissue depends on functioning cells. The most common use for thyroid scan is to assess if a nodule is functional or not. A functional/hot nodule may cause hyperthyroidism but is not likely to be malignant. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/003829.htm. ...Read more

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Does autoimmune disease cause cytokine storm or calm it down due to immune dysfunction?

Does autoimmune disease cause cytokine storm or calm it down due to immune dysfunction?

CytoKine storm: When our body detects foreign microorganisms indicating an infection, our body might respond by over-protecting the site of infection. The body may race so many antibodies to the infection site that they collect in a cytokine storm. When the infection is in the lungs, for example, a cytokine storm can potentially block airways and result in suffocation. Medical researchers have identified the caus. ...Read more

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Could thyroid eye disease cure itself once hormone levels are balanced?

Could thyroid eye disease cure itself once hormone levels are balanced?

Graves eye disease: Graves eye disease tends to run a separate course from the hyperthyroidism. Fixing the hyperthyroidism will improve the lid lag, which gives the appearance of a "stare". But the proptosis ("bugging out"), inflammation, swelling, double vision, may not improve. You should see a specialist, starting with an endocrinologist, to see if you should be on steroids, have surgery, or other treatments. ...Read more

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Is there research into any genetic, autoimmune or other condition that links nerve sheath disorders (tarlov cysts, nerve sheath tumor) with autoimmune hypophysitis targeting acth cells? Ctla-4 gene?

Is there research into any genetic, autoimmune or other condition that links nerve sheath disorders (tarlov cysts, nerve sheath tumor) with autoimmune hypophysitis targeting acth cells? Ctla-4 gene?

None that I find: I cannot locate any literature on the two conditions being studied simultaneously. Perhaps one of my more research savvy colleagues here will come up with something . Great question by the way. ...Read more

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Controversy surrounds those patients with a suppressed tsh. Isn't it true that when a hypothyroid patient starts taking exogenous th, a negative feedback system reduces the pituitary gland's output of tsh. This decreases the thyroid gland's output of en

Controversy surrounds those patients with a suppressed tsh.  Isn't it true that when a hypothyroid patient starts taking exogenous th, a negative feedback system reduces the pituitary gland's output of tsh.  This decreases the thyroid gland's output of en

Endo feedback: With primary hypothyroidism, TSH is elevated in an effort to push the thyroid gland to make more thyroxine. Treatment with levothyroxine indeed signals the pituitary to reduce TSH output. Secondary is when either/or pituitary +/- hypothalamus is damaged but unable to produce tsh. Then, thyroxine levels drop but the pituitary can't respond. Tsh can't monitor treatment but free T4 levels can. ...Read more

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Since sjogrens can damage the thyroid would tpo be produced because of sjogrens and cause hashimotos, or is hashi always a separate disease?

Since sjogrens can damage the thyroid would tpo be produced because of sjogrens and cause hashimotos, or is hashi always a separate disease?

Separate diseases: There is a significant co-existence of these two diseases but they are separate diseases. Both are auytoimmune in nature but the presence of sjogren's disease does not cause the development of thyroid antibodies nor the development of hashimoto's. ...Read more

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Autoimmune pancreatitis caused by autoimmune thyroiditis. Will taking out thyroid fix the pancreatitis?

NO: Autoimmune thyroid is caused by the immune system attacking the thyroid. Autoimmune pancreatitis is caused by the immune system attacking the pancreas. consequently, if you remove the thyroid the immune system is still present and still causing autoimmunity to the pancreas. ...Read more

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What body functions are affected by hashimoto's thyroiditis?

What body functions are affected by hashimoto's thyroiditis?

All of them.: While the inflammation (the -itis part of thyroiditis) affects only the thyroid, if this causes the thyroid levels to drop, every tissue in the body can be affected - simplistically this can cause a slow down of the heart, the GI tract, the liver, the muscles, and the brain. Because the cells are slower to convert food energy to heat or work energy there is less energy to get things done. ...Read more

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Blood test shows my immune system is attacking the thyroid hormone, st this point the thyroid is shown to be unharmed. Can this be permanently cured?

Blood test shows my immune system is attacking the thyroid hormone, st this point the thyroid is shown to be unharmed. Can this be permanently cured?

Endocrinologist: You have what is called autoimmune thyroid disease. You need to be evaluated by an endocrinologist, who specializes in hormonal diseases, to better understand your diagnosis and determine if therapy is warranted. ...Read more

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Is there an autoimmune disease that targets attacks, kills the nerves in the entire body which affects personality behavior loss of emotions, feelings?

No but: It doesn't sound autoimmune. Depression doesn't require an autoimmune disease. It can make your mind attack itself, be associated with physical pain, loss of energy, insomnia, crying spells. Get seen, treatment will make difference. Only 30% of people get acceptable improvement on 1 med, insomnia, pain, low energy all need attn. Therapy and meds together is best if u have this problem. Gd luc. ...Read more

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Does multinodular goiter with slightly elevated thyroid antibodies possibly mean an autoimmune thyroid disease?

Possibly: Thyroiditis (which can be immune based) is the most common cause of a multinodular goiter. Have you doctor test for tpo antibodies if you're concerned. ...Read more

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What does an increased number of mast cells in stress-indiced urticaria biopsy indicate? Previously diagnosed w/connective tissue autoimmune disease.

What does an increased number of mast cells in stress-indiced urticaria biopsy indicate? Previously diagnosed w/connective tissue autoimmune disease.

Histamine!: Mast cells contain histamine the chemical start in "immunology" parlance causes itching, leagage of fluid from blood vessels, even burning. This typical in an urticarial bx! ...Read more

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Is hashmotos reversible? Or does the immune system attack other organs after the thyroid can't the immune system be calmed down

Hashimoto's: Not generally reversible. Usually progresses to destruction of the thyroid gland so that thyroid hormone replacement is required. Antibodies in Hashimotos are specific to the thyroid, so limited in that sense. There are some who develop other autoimmune diseases but those diseases are generally considered separately. ...Read more

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Why would autoimmune disorders make the thyroid gland produce excessive thyroxine?

Antibodies: Some auto-antibodies sit on the thyroid cells and make them over produce thyroid hormone. Other autoantibodies can cause the exact opposite. ...Read more

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Does high tpoabs slowly completely destroy thyroid gland?If so, how long will it take?Do they attack the other body parts once thyroid stop working?

Does high tpoabs slowly completely destroy thyroid gland?If so, how long will it take?Do they attack the other body parts once thyroid stop working?

TPO hypothyroid: Under activity of thyroid can develop at variable intervals some may not even develop functional problems higher titers female sex family history may help tpo is a specific antibody does not attack other tissues can be associated with eye and skin infiltrative disease. ...Read more

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Under what circumstances can fluoride compounds destroy the thyroid gland?

Under what circumstances can fluoride compounds destroy the thyroid gland?

Very high dosages: Some studies have shown that very high dosages of Fluoride can adversely effect the thyroid gland. Any reports saying that the low dosages used to promote dental care have any adverse effect on the thyroid are simply fear mongering and are not backed up by scientific studies. ...Read more

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Can you tell me exactly when is it time to surgically remove the thyroid gland due to multinodular thyroid disease?

Concern for Cancer: Generally only if there is concern for a potential thyroid cancer (i.e. A nodule is enlarging on ultrasound or a needle biopsy suggests cancer). Occasionally, the thyroid is also removed if it becomes very large and is pressing on other structures (e.g. The airway), though this is rarely necessary. ...Read more

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Could having hashimoto's disease cause a person's thyroid gland to shrink in size?

Yes, but often enlar: The autoimmune process in hashimoto's thyroiditis can cause shrinking, but often involves enlargement of the thyroid gland, especially in the early phase of the disorder. You should see an endocrinologist for any change in thyroid size. ...Read more

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With hashimoto's disease how long does it take for the thyroid gland to get better?

With hashimoto's disease how long does it take for the thyroid gland to get better?

With Medication: Hashimoto's disease is an autoimmune destruction of the thyroid gland (painless). Lymphocytes enter the gland to cause inflammation and scarring. The damage is usually permanent. Fortunately, with the availability of thyroid hormone replacement, levothyroxine, it is a very easy condition to manage- 1 pill daily. It can take weeks to feel better after starting medicine, but it works! ...Read more

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Hello, my girlfriend diagnosed with enlarged thyroid gland with heterogeneous echo pattern consider thyroid parenchymal disease, what does that mean?

Hello, my girlfriend diagnosed with enlarged thyroid gland with heterogeneous echo pattern consider thyroid parenchymal disease, what does that mean?

Thyroid big: 24 M from Philippines states girlfriend has enlarged thyroid with echo showing scatter suggestive of thyroid disease. This means she has an enlarged thyroid. But the cause cannot be determined. She needs to see a thyroid specialist/endocrinologist to figure out what is going on. They will know what is the most likely prob in your part of the world and how to best evaluate and treat her if needed. ...Read more

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Can someone get graves disease if they've had their thyroid gland removed?

No,if entire gld rem: Unless there is some ectopic thyroid tissue sitting somewhere else in the body , which is rare , if the entire gland is removed grave's reoccurance is unlikely. ...Read more

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I have just been diagnosed with graves disease (april 1), are there any benefits to having the thyroid gland removed?

I have just been diagnosed with graves disease (april 1), are there any benefits to having the thyroid gland removed?

Easier treatments: Treatment with radioactive iodine is less invasive and generally effective. Surgery is usually not the first choice. See this site for more info. http://www.mayoclinic.com/health/graves-disease/ds00181. ...Read more

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Tsh 0.313 told I have hyperthyroidism, enlarged thyroid gland. Losing weight, heart palp, & trouble sleeping. What are my chances of Graves' disease.

Hyperthyroidism: There are several causes of hyperthyroidism, the most common of which are Graves disease and Hashimoto's thyroiditis. Given the secondary impacts on other organs, the diagnosis needs to be clarified and determined as early as possible so treatment can begin. Both of these causes could be associated with the symptoms you describe. Get your further testing done and get treatment going. ...Read more

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Can hoshimotos automimmune disease of the thyroid make the submandibular glands enlarged? Or any salivary glands enlarged?

Possible: Auto immune etiology is the reason for thyroid disease in Hashimoto's .The same pathology -autoimmune if directed against the salivary glands Vs lymph nodes is possible. But make sure that the thyroid disease is Hashimoto's and not thyroid cancer. ...Read more

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What does the thyroid gland do?

Endocrine Gland: It is an endocrine gland which produces thyroxin hormone which controls the metabolism in every cell in the body.It produces 80 to 90% T4 and 10 to 20 %T3. These control rate of metabolism and affect the growth and rate of functions of many cells in the body it is located in the neck. It also controls body's temperature ...Read more

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What happens when a thyroid gland grows back?

Why was it removed?: You need to address the issue of why it was removed in the first place. Was it hyperthyroid? Nodules? Cancer? There are lots of issues and it is best you sort this out with your endocrinologist. ...Read more

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What will happen if the thyroid gland is removed?

What will happen if the thyroid gland is removed?

Thyroidectomy: If all/most of the gland is removed, you will become hypothyroid, which is easily treated with levothyroxine, and you will feel fine. Potential complications of surgery is removal of the parathyroids, or damage to the nerve to the vocal cords, but this is uncommon when performed by a surgeon who does this procedure regularly. ...Read more

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What does grossly homogeneous thyroid gland mean?

What does grossly homogeneous thyroid gland mean?

No nodules: No lumps or bumps. Sort of filler-language to reassure. Most thyroids are grossly homogeneous. ...Read more

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What are the normal measurements of thyroid gland?

Everyone differs: There are standard ranges of normal, but many, many patients feel better when they're treated not by the numbers, but by their symptoms. Google "stop the thyroid madness" for more info. Weird name, helpful site. ...Read more

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What is the definition or description of: thyroid gland?

Endocrine Gland: It is an endocrine gland which produces thyroxin hormone which controls the metabolism in every cell in the body.It produces 80 to 90%t4 and 10 to 20 %t3. These control rate of metabolism and affect the growth and rate of functions of many cells in the body it is located in the neck. ...Read more

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Why thyroid gland is unique ? please i need the answer as soon as...

Why thyroid gland is unique ?
please i need the answer as soon as...

Thyroid: Please go online and look up all the information you need to see if your thyroid is or is not abnormal. ...Read more

Thyroid Gland (Definition)

It is an endocrine gland which produces thyroxin hormone which controls the metabolism in every cell in the body.It produces 80 to 90%t4 and 10 to 20 %t3. These control rate of metabolism and affect the growth and rate of functions of many cells in the body it is ...Read more


Dr. Sanjiv Kaul
13 doctors shared insights

Thyroid (Definition)

The thyroid is an endocrine gland that sits in the lower part of the neck. It produces thyroid hormone - which ...Read more