Top
20
Doctor insights on: Autoimmune Diseases With Normal Bloodwork

Share
1

1
Is a normal but lowering globulin indicative of autoimmune disease all other bloodwork normal?

Is a normal but lowering globulin indicative of autoimmune disease all other bloodwork normal?

See below: A decreasing globulin is not necessarily associated with an autoimmune process. ...Read more

Dr. Tracy Lovell
492 doctors shared insights

Autoimmune Disease (Definition)

In auto immune disease the enemy is from with in . As name implies "auto" is self and "immune " is immune system . One 's own immune system for unknown reason turns against self and destroys or damages tissues or cells . List of auto immune disease are many and growing . End result is destruction of of tissues such as thyroid , pancreas or cells such as white ...Read more


2

2
My 4 yo son recently had some bloodwork done. C4 complement level was 14, C3 complement was 148. Risk for autoimmune disease? C4 is just barely normal

My 4 yo son recently had some bloodwork done. C4 complement level was 14, C3 complement was 148. Risk for autoimmune disease? C4 is just barely normal

No: And depends on history, physical exam and why the test was ordered. Auto immune disorders are vast, not a single blood test result makes the diagnosis, which is rather a complex one. Ask your doctor about the result and the logic behind ordering the test, wish you and your son wellness ...Read more

3

3
Do autoimmune diseases normally cause inflammation?

Abnormally: The basis of autoimmune disease is inflammation. No inflammation then no autoimmune disease or autoimmune disease that is under control. ...Read more

4

4
If I have indifferentiated autoimmune disease symptoms and my blood counts have been consistently "low normal" for years, what could that mean?

If I have indifferentiated autoimmune disease symptoms and my blood counts have been consistently "low normal" for years, what could that mean?

R/O CVD: CVD = COLLAGEN VASCULAR DISEASE. The classic one are LUPUS & RHEUMATOID ARTHRITIS. UCVD=UNDIFFERENTIATED COLLAGEN VASCULAR DISEASE. This means that you have some but not all the criteria to meet a specific diagnosis. Make sure to follow up with s good RHEUMATOLOGIST. ...Read more

5

5
Is it normal to be diagnosed w/an autoimmune disease after beating cancer?

Is it normal to be diagnosed w/an autoimmune disease after beating cancer?

Yes it can: I have seen sjogren's and rheumatoid diagnosed after lymphoma. Have seen rheumatoid arthritis and psoriatic arthritis diagnosed after breast and prostate. Are they a coincidence---hard to say, but in the case of lymphoma---rituxan is used to treat lymphoma and it also approved to treat rheumatoid as well---it targets the same cd19/cd20 cell that is involved in both processes. ...Read more

See 2 more doctor answers
6

6
Are cataracts normal at age 46? Or could it be associated with my disc degeneration...Or be an underlying autoimmune disease?

Are cataracts normal at age 46? Or could it be associated with my disc degeneration...Or be an underlying autoimmune disease?

Can occur at any age: You are a bit young, but cataracts can occur at any age and even in newborns (congenital cataracts). Incidence increases with age. However, chronic inflammation within the eyes (uveitis) can lead to early cataract. Diabetes can lead to early cataract. Systemic or local (injections or inhaled or topical) steroids (prednisone type meds) can cause early cataract. ...Read more

See 1 more doctor answer
9

9
Esr is elevated but my ANA and CRP are normal! does this mean that i don't have an autoimmune disease?

Esr is elevated but my ANA and CRP are normal! does this mean that i don't have an autoimmune disease?

Autoimmune disorders: Esr is an inflammatory marker tha is elevated in inflammatory disorders, anemia , pregnancy, , kidney cancers , tb, lymphoma to name a few. It measures rate at which red cells sediment in a test tube in 1 hour. It is used more to monitor response to treatmemt is such disorders and helps in diagnosis of certain conditions. Esr can be elevated with negative ANA in several autoimmune disorders. ...Read more

See 1 more doctor answer
10

10
Is it normal for a 17yo to have iritis? I'm worried that I have an autoimmune disease as well because the iritis has affected both my eyes.

Is it normal for a 17yo to have iritis? I'm worried that I have an autoimmune disease as well because the iritis has affected both my eyes.

Not normal : You need to see an eye doctor for further evaluation. The bilateral nature of your disease is concerning and needs prompt evaluation and treatment. ...Read more

See 2 more doctor answers
11

11
Do you think if you have any kind of autoimmune disease? Like lupus or anything? Or would it have sawn in blood test. If blood result is normal.

See details: There are literally scores of autoimmune diseases. Some can be diagnosed with the help of lab tests and some cannot. Lupus can be present even if all autoantibody testing is negative. However, this is a rare occurrence. ...Read more

12

12
I had the standard blood tests for autoimmune diseases (no symptoms) all the tests came back normal except ANA of pos 1.4. Should i be concerned?

I had the standard blood tests for autoimmune diseases (no symptoms)  all the tests came back normal except ANA of pos 1.4.  Should i be concerned?

See below: Close to 30% of patients will have positive ana. If you did not have symptoms of autoimmune disease, it is not clear to me why this was performed. Odds are in your favor that you probably have nothing to worry about with you currently reporting no symptoms. ...Read more

See 1 more doctor answer
13

13
Can someone with normal lab results still have lupus or RA or othe autoimmune diseases?

Can someone with normal lab results still have lupus or RA or othe autoimmune diseases?

Possibly: About 98-99 percent of people with Lupus have a positive ANA test so it be unlikely to have lupus with a negative ANA blood test. On the other hand, in rheumatoid arthritis, especially in the early phases, a much larger minority of people may have a normal Rheumatoid factor test (but many of those people may have a positive CCP ab test that is seen in RA). Bottom line: possible but unlikely. ...Read more

14

14
My 4 yo son has had turbid urine from time to time. Urinalysis normal. Blood work all normal except c4 level of 14. Risk for autoimmune disease?

My 4 yo son has had turbid urine from time to time. Urinalysis normal. Blood work all normal except c4 level of 14. Risk for autoimmune disease?

Turbid urine: hello, TURBID URINE is NOT NORMAL URINE. This is usually caused by prot, blood or infection in the urine. I do not believe those urine test results.Please take him to a PEDIATRICIAN and have them re-test his urine for blood, white cells and protein both qualitatively and QUANTITATIVELY. A Pediatrician will know what to do next if there is actually something there. This SHOULD NOT BE IGNORED.thanks ...Read more

See 1 more doctor answer
16

16
Should I ask my doctor to check for other autoimmune diseases if I have hashimotos disease? Meds not helping symptoms even when thyroid level normal

Yes but: If the thyroid level is normal, then your symptoms are not caused by the thyroid but something else. Although you may be at a somewhat higher risk to develop another autoimmune disease , your problem may or may not be an autoimmune one. ...Read more

17

17
I have fibromyalgia. I have many symptoms of autoimmune diseases.Lupus & RA test normal.ANA & CRP test are positive and elevated.What does this mean?

Exam: You should see a rheumatologist to undergo a full history and exam. No single test can diagnose a rheumatological disease. ANA alone is not indicative of sle. The titer and type is imp. High CRP again in a non specific sign of inflammation. So should see a rheumatologist and have this a exam. ...Read more

20

20
My wife has a chronic throat pain and inflammation which is not explained by reflux and all her blood tests come up normal. Could she have an autoimmune disease which has gone undetected?

My wife has a chronic throat pain and inflammation which is not explained by reflux and all her blood tests come up normal. Could she have an autoimmune disease which has gone undetected?

Throat pain: Once the common things are excluded and symptoms persist, then one should consider less common causes of throat pain such as autoimmune diseases, achalasia, or ulcerations. Blood tests can only go so far, and endoscopy with possible biopsy may be needed to find an explanation. ...Read more

Autoimmune (Definition)

The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more