Top
20
Doctor insights on: Autoimmune Biliary Cirrhosis

Share
1

1
Is primary biliary cirrhosis hereditary?

Is primary biliary cirrhosis hereditary?

Basically no: There's a pair of genes that carry the ability to develop the disease and these run in families, but it's not inherited like sickle cell, huntington's or some of the other familiar entities. http://www.medicalnewstoday.com/releases/151640.php. ...Read more

Autoimmune (Definition)

The immune system developed to tell our own, normal cells (self) from foreign and abnormal cells (non-self). This lets the immune system eliminate viruses, bacteria, fungi and cancer cells from our body without harming normal cells. Sometimes the immune system fails to tell self from non-self and it attacks normal cells, for example in ...Read more


5

5
Pathophysiology of liver cirrhosis?

Pathophysiology of liver cirrhosis?

See below: Scar tissue in the liver as a result of different kinds of injuries. The significance is related to the chronicity for the injury and especially whether the injury is ongoing. ...Read more

6

6
Why is igm elevated in primary biliary cirrhosis (cholangitis)?

Why is igm elevated in primary biliary cirrhosis (cholangitis)?

Immune dysregulation: The immune system is not functioning normally in primary biliary cirrhosis. That and the chronic inflammation contrive to raise IgM. ...Read more

7

7
What's parenchymatous liver disease?

What's parenchymatous liver disease?

Liver Disease: The cells of the liver are called the parenchymal cells and make up the bulk of the liver. Therefore, this means that you have disease of the liver cells. Other cells in the liver include the bile duct cells (cholangiocytes), white blood cells (Kupffer cells), and storage cells (stellate cells). ...Read more

8

8
What is chronic liver parenchymal disease with cirrhosis; varices and ascites?

What is chronic liver parenchymal disease with cirrhosis; varices and ascites?

This sounds serious: To translate, you have liver cell damage and scarring (cirrhosis), which caused abnormally elevated portal vein pressures which caused venous distention in esophagus (varices). You also developed fluid in abdominal cavity, because of the high portal vein pressure. This imaging study is showing advanced stage of liver disease. You must get a specialist to treat you. ...Read more

9

9
Could liver function tests reveal autoimmune hepatitis?

Could liver function tests reveal autoimmune hepatitis?

Yes: Liver function tests are often elevated in autoimmune hepatitis. This is a non- specific test. If the liver function tests are elevated additional diagnostic tests will be necessary. The anti smooth muscle antibody is one of the most important in pointing to this diagnosis. Tests for other liver diseases such as hepatitis and primary biliary cirrhosis are usually part of the evaluation. ...Read more

11

11
What differentiates primary biliary cirrhosis from other types of cirrhosis?

What differentiates primary biliary cirrhosis from other types of cirrhosis?

Location of inflam: Agree with dr. Edmisson. Pbc is autoimmune disease affecting bile ducts; can eventually lead to progressive liver disease and cirrhosis (scarring). Othe types of cirrhosis usually involve inflammation of the liver cells, due to infection (like hep b, c), toxic chemicals, metabolic disease e.g.Nonalcoholic fatty liver (seen in obesity, diabetes) iron overload, damage from alcohol, autoimmune. ...Read more

See 1 more doctor answer
12

12
Is liver cirrhosis curable?

Is liver cirrhosis curable?

No: No, but you stop it from progressing further by eliminating the cause: abstaining from alcohol or treating hepatitis b or c. ...Read more

14

14
Can lupus cause non-alcoholic fatty liver?

Can lupus cause non-alcoholic fatty liver?

Autoimmune hepatitis: Lupus is associated with autoimmune hepatitis, not nash (non-alcoholic fatty liver). Nash is commonly see in settings of obesity, excessive alcohol intake, diabetes, high cholesterol. Both entities can occur together when respective risk factors for both exist. ...Read more

16

16
Fatty liver NASH wilson's disease, tell me more?

Fatty liver NASH wilson's disease, tell me more?

Confusion: Clinically and under the microscope, wilson's (rare) can look treacherously like alcoholic liver disease or non-alcoholic steatohepatitis (nash, very common). In fact, even weighing the copper in the liver can be misleading because the biopsy may be regenerative nodules. A urinary copper check is part of my preferred workup, and consider a genetic check. ...Read more

19

19
Can liver disease cause cholestasis?

Can liver disease cause cholestasis?

Sure, but...: Liver disease comes in many varieties and manifestations: cholestasis (either intrahepatic or extrahepatic) with jaundice; infiltrative (like fatty liver, amyloidosis); fibrotic (trending toward cirrhosis); congestive (blood backs up into the liver); ischemic; shock injury; toxic (either metabolic or drug-related); hepatitis (infectious or otherwise, the liver cells are sick); familial; cancer... ...Read more

20

20
Is autoimmune hepatitis fatal?

Can be: If left untreated, autoimmune hepatitis can progress to liver failure. If in liver failure, it will be fatal unless you have a liver transplant. However, you can prevent progression of the disease with medications. ...Read more

Dr. Neigatha Graney
1 doctor shared a insight

Biliary (Definition)

Biliary means anything related to the production, storage, secretion, or flow of bile, whether in the liver, bile ducts, gallbladder, ...Read more


Upper Abdomen (Definition)

Draw a transverse line through the umbilicus and the upper abdomen includes every part of the belly above this line and below the ...Read more