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Doctor insights on: Atypical Mole Melanoma Syndrome

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Pathology moderate atypical dysplastic nevus, recommend further excision. Is this cancer/melanoma?

Pathology moderate atypical dysplastic nevus, recommend further excision. Is this cancer/melanoma?

Not yet: It may develop into a malignancy but is not yet. The borders may be incompletely excused, or te pathologist may feel that a wide enough clear margin has not been achieved. ...Read more

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Dr. Mike Bowman
957 doctors shared insights

Skin Cancer (Definition)

A condition in which some element of your skin--which is one of the most complex organs in the body--degenerates into cancer. The three most common types of skin cancer are: basal cell, squamous cell, and melanoma which occur in that order and degree of aggressiveness. Although heredity plays a major role, sun exposure and tobacco use and ...Read more


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Biopsy shows spitz nevus cells under another type of benign mole. Melenoma can't be ruled out yet. Can melanoma grow under a benign mole?

Biopsy shows spitz nevus cells under another type of benign mole. Melenoma can't be ruled out yet. Can melanoma grow under a benign mole?

Yes: In fact, this is fairly common. No one knows where spitz nevus leaves off and a melanoma capable of metastasizing begins. This is one of the hardest calls in pathology, and some say it's impossible. The burning question will be whether to do additional surgery. ...Read more

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What causes dysplastic nevi syndrome?

What causes dysplastic nevi syndrome?

It is a familial: condition, but a lot is still not understood about transfer in families. Patients with this syndrome are at higher risk for abnormal moles and melanoma. So regular checks with dermatology is imperative ...Read more

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Mole grew back 6 weeks after shave. Report compound melanocytic nevus architectural disorder moderate cytologic atypia. What's this mean, melanoma ?

Mole grew back 6 weeks after shave. Report compound melanocytic nevus architectural disorder moderate cytologic atypia. What's this mean, melanoma ?

Seek 2nd opinion: Recurrence of a mole makes it likely that it is a melanoma. You should get further surgery done by a melanoma expert(surgical Oncologist). It always useful to seek 2 or 3 opinions and go with the aggregate of the recommendation, provided to you. ...Read more

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Is dysplastic nevus benign?

Is dysplastic nevus benign?

DYSPLASTIC NEVUS: THIS IS A NEVUS (MOLE) WITH AN ABNORMAL DEVELOPMENT OR GROWTH OF CELLS. THIS SHOULD BE SEEN BY A DERMATOLOGIST WHO WILL DECIDE WHETHER TO EITHER WATCH IT PERIODICALLY OR TO CUT IT OUT -- BIOPSY IT -- UNDER LOCAL ANESTHESIA AND THEN SEND THE SAMPLE TO A SPECIALIZED PATHOLOGIST FOR AN EXAMINATION. ...Read more

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Is dysplastic nevus with moderate atypia malignancy?

Is dysplastic nevus with moderate atypia malignancy?

No: Dysplastic nevus is not cancer, but left alone these can progress to cancer. Best to have it removed, that is all the treatment necessary. ...Read more

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Junctional nevus with cytologic atypia concern?

Junctional nevus with cytologic atypia concern?

Yes : Depending on the degree of atypia, most surgeons recommend excision with clear margins to reduce the risk of developing skin cancer (melanoma being the most concerning). Certainly excise if moderate to severe atypia. ...Read more

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Is seborrheic keratosis a malignant skin cancer tumor?

Is seborrheic keratosis a malignant skin cancer tumor?

No: Sk's are nonmalignant tumors, nor are they premalignant. They often grow on sun damaged skin, so they often show up in the same areas which are at risk for skin cancers. Sk's require no treatment. See a md for eval & diagnosis. ...Read more

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What is dysplastic nevus as compared to melanoma?

What is dysplastic nevus as compared to melanoma?

You have asked...: ...One of the most controversial questions in dermatology. One faction believes that dysplastic nevi are precursors of melanomas, and should be excised before they become melanomas. Another faction believes dysplastic nevi are benign moles that never become melanomas. There is evidence to support both arguments. ...Read more

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My pathology report states junctional and lentiginous melanocytic nevus, extending to the peripheral edge. Is this melanoma?.

My pathology report states junctional and lentiginous melanocytic nevus, extending to the peripheral edge.  Is this melanoma?.

Mole, not cancer: Here is a translation of your path report: Junctional- location as it relates to depth in the skin, the junction between epidermis and dermis. lentiginous- means flat dark spot, melanocytic- made up of pigment cells (melanocytes), nevus - a lesion that contains nevus cells a type of melanocyte, aka "mole". This is a benign spot that appears to have been completely removed. Not a malignancy. ...Read more

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What chromosome is congenital melanocytic nevi syndrome?

No specific link: The congenital melanocytic nevus syndrome is considered sporadic in its occurrence.A few available studies of biopsy material have found abnormalities on the 1st, 12th or 19 th chromosome but no consistent pattern is reported.See the recent article : www.Ncbi.Nlm.Nih.Gov/pmc/articles/pmc2994429. ...Read more

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Does an atypical mole usually turn into melanoma?

Atypical nevi: Atypical moles(nevi), prescancerous nevi, dysplastic nevi are classified as mild, moderate and severe. After severe is melanoma. It is believed than normal moles go through this progression to become a melanoma. Thus, skin screening is important to pick up the precancerous nevi before they turn into melanoma. ...Read more

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Is the neuroleptic malignant syndrome really malignant?

Is the neuroleptic malignant syndrome really malignant?

NO!: Neuroleptic malignant syndrome (nms) is a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic drugs. Nms typically consists of muscle rigidity, fever, autonomic instability, and cognitive changes such as delirium, and is associated with elevated plasma creatine phosphokinase. ...Read more

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Is hydatidiform mole hereditary?

Is hydatidiform mole hereditary?

No.: A hydratidiform mole occurs in a molar pregnancy. This is an abnormal form of pregnancy where a egg that had lost its dna becomes fertilized by sperm (complete mole) or an egg becomes fertilized by two sperm or a sperm that has duplicated itself (partial mole). Molar pregnancies occur randomly, in about 1/1000 pregnancies, and cannot survive. They can develop into choriocarcinoma, a form of cancer. ...Read more

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What constitutes stage 4 melanoma on a superficial mole that has gone malignant?

Metastasis: Stage IV (4) melanoma is the highest stage that a melanoma can reach. It is diagnosed by finding distant spread or metastasis to other parts of the body. Stage is different from clark's levels and breslow levels, although these can impact lower stages. (ajcc cancer staging manual, 7th ed., 2010). ...Read more

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Does a completely removed potential precursor to malignant melanoma atypical nevus return in same place? Does it return as a malignant melanoma?

No: If it was removed completely, it will not return. This is why it's good to take margins. If it does recur at the site, it will probably still be a benign lesion, but keep an eye on it. The most important thing about a diagnosis of atypical nevus is that it warns you're likely to get a melanoma someplace else. Keep an eye on all your skin (partner, dermatologist) and quick removal will save you! ...Read more

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Dysplastic nevus, or atypical moles, and they are benign lesions that resemble early melanoma, and about 1 in 10 million americans willmelanoma, what to do?

Watch carefully: Dysplastic nevi are potentially serious in that they can convert to infiltrating melanoma. In children with spitz nevus, they look malignant but never convert. In patients with neurofibromatosis there is a high incidence of dysplastic nevi and since many are present they are watched for changes in shape, darkening in color or redness around the lesion suggesting that they are converting. ...Read more

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What is atypical Nevus?

What is atypical Nevus?

Dysplastic nevus: Researchers have shown that dysplastic nevus or atypical moles are more likely than ordinary moles to develop into a type of skin cancer called melanoma. Make sure your nevus is managed by a dermatologist. https://en.wikipedia.org/wiki/Dysplastic_nevus ...Read more

Dr. Coyle Connolly
1,107 doctors shared insights

Moles (Definition)

A mole (also called a nevus) is a localized overgrowth of pigment-producing cells (melanocytes) in the skin. Most moles are benign. However, these cells can become cancerous. This is known as melanoma, ...Read more


Dr. Travis Kidner
2,633 doctors shared insights

Melanoma (Definition)

Cancer of the melanocyte cells. Melanocyte cells determine the color of your skin. Although these cells are primarily found in your skin, they can also be found in the bowel ...Read more