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Doctor insights on: Atypical Migraines Lupus Periventricular White Matter Basal Ganglia

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My mother, 84, MRI scan> subacute infarcts, bilateral frontal lobes, small vessel ischematic changes inthe basal ganglia, periventricular white matter?

My mother, 84, MRI scan> subacute infarcts, bilateral frontal lobes, small vessel ischematic changes inthe basal ganglia, periventricular white matter?

Small vessel disease: Mri in a 84 years old lady showing infarcts and small vessel disease means she is having ministrokes. That is very common in that age group. If she has heart disease or carotid artery disease or risk factors like high BP or diabetes or high lipids they should be controlled and she should follow up with her dr who can give her further recommendations. ...Read more

White Matter (Definition)

White matter is one of the two components of the central nervous system and consists of glial cells and myelinated axons that transmit signals from one region of the cerebrum to another and between the cerebrum and lower brain centers. White matter tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid ...Read more


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Had a MRI brain scan.Report says prominent virchow-robin spaces in fronto-parietal white matter and basal ganglia.No other abnormality, is this normal?

Had a MRI brain scan.Report says prominent virchow-robin spaces in fronto-parietal white matter and basal ganglia.No other abnormality, is this normal?

Yes: The virchow-robin spaces are peri vascular spaces normally seen around blood vessels and are not associated with any central nervous system pathology. Please try not to worry as the report you cite is fine. Well wishes. ...Read more

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Please point me to where i can get t1 brain atlas and its labelling for basal ganglia segmentation?

Please point me to where i can get t1 brain atlas and its labelling for basal ganglia segmentation?

Available online: Here are some T1-weighted MRI brain atlases that may help with your basal ganglia segmentation question: http://www.med.harvard.edu/aanlib/cases/caseM/case.html , http://thebrainobservatory.ucsd.edu/cortex-1 , and http://www.dartmouth.edu/~rswenson/Atlas/AxialT1MRI/index.html ...Read more

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I have a lesion on the left side of my brain in the basal ganglia and i also have left leg paralysis. What could be the cause?

I have a lesion on the left side of my brain in the basal ganglia and i also have left leg paralysis.  What could be the cause?

Paralysis: Left basal ganglia lesion would cause right sided weakness. Left leg paralysis would be from a right sided lesion in the brain above the brain stem. A spinal cord lesion on the same side or below where the corticospinal fibers cross in the brain stem would cause left leg weakness. See you neurologist or neurosurgeon to identify the source of the left leg weakness. ...Read more

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My new born baby has just been diagnosed with an insult to the brain-basal ganglia. What does this mean?

My new born baby has just been diagnosed with an insult to the brain-basal ganglia. What does this mean?

Unclear yet: Speak with your medical team on their next rounds and ask the charge nurse to help coordinate a " care conference' with your family and your baby's providers. Its unclear at this time how this will affect the baby's future development. They will probably call in further specialists to discuss the specific typical outcomes with this particular injury. Hang in there! ...Read more

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What do you suggest if my new born baby has just been diagnosed with an insult to the brain-basal ganglia?

What do you suggest if my new born baby has just been diagnosed with an insult to the brain-basal ganglia?

Assemble team: A team approach to monitoring and treatment would be best. Your general pediatrician can help coordinate with a neurologist, neurosurgeon, developmental pediatrician and physical therapist. Babies have remarkable rehabilitative potential, so keep positive thoughts! ...Read more

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I had an MRI of the brain which showed a small old left basal ganglia lacunar infarction?

A risk factor: Regardless of the age of the prior stroke, you need to fully assess all relevant risk factors and start a protective anti-platelet med such as aggrenox, and perhaps lipitor (atorvastatin). Issue is not the prior lacunar infarct, but what may occur in future instead. ...Read more

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S+s of end stage primary brain cancer, (aa iii) r medial temporal lobe, diffuse numerous cells. Growing!/brainstem and posterior temp./basal ganglia?

S+s of end stage primary brain cancer, (aa iii) r medial temporal lobe, diffuse numerous cells. Growing!/brainstem and posterior temp./basal ganglia?

Ask for more info: Signs and symptoms can vary greatly with any 'end-stage' cancer. Things like if it has spread to other organs, impacting functional status and alertness (sleeping more, in bed most of the time), causing pain/seizures, and so on. His doctors can maybe determine what is most likely. If not involved already ask for hospice or palliative care help as they could also help answer what the s/s might be. ...Read more

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Result for my brain MRI -asymmetric decreased attenuation in the left basal ganglia, variant dilated perivascular spaces or punctate chronic lacune. ?

Result for my brain MRI -asymmetric decreased attenuation in the left basal ganglia, variant dilated perivascular spaces or punctate chronic lacune.  ?

MRI report: This is language used in radiology to describe what they see. Ordinarily, they cannot distinguish a small stroke (lacune) from a perivascular space. A "puntate lacune" though is very small. It is probably just the side view of a blood vessel (aka perivascular). Do you smoke? Do you have high blood pressure? Do you have diabetes mellitus? Atrial fibrillation? These are stroke risk factors. ...Read more

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Pet/ct scan of brain shown bilateral temporal(more severe on left side)parietal, thalami & basal ganglia hypo metabolism.What does it mean, pl advice.

Pet/ct scan of brain  shown bilateral temporal(more severe on left side)parietal, thalami & basal ganglia hypo metabolism.What does it mean, pl advice.

MaybeNothing: Pet/ct can show a region of hypometabolism, yes. But you describe many areas, including bilateral areas. That is much harder to accurately define on these kinds of tests, and results should be viewed with caution. Also, remember that the metabolism images should fit with what is wrong with the patient. ...Read more

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I had a brain ct and they said everything was good/ normal. I just read report and it said Bilateral basal ganglia calcification/mineralization is noted. What does that mean? I am 42 and went in for symptoms that mirrored stroke a heart attack symptoms, b

I had a brain ct and they said everything was good/ normal. I just read report and it said Bilateral basal ganglia calcification/mineralization is noted. What does that mean? I am 42 and went in for symptoms that mirrored stroke a heart attack symptoms, b

Scarring, old injury: Calcification (buildup) of the basal ganglia or anywhere in the brain is a healing process for an injury, whether the cause is vascular, genetic (Parkinson's disease), infection, or other cause, that happens over many yrs. Ur description of ur symptoms is sparse. The CT is used to check if any abnormality EXPLAINS YOUR IMMEDIATE SYMPTOMS. Any other "abnormality" is irrelevant to ur primary doctor. ...Read more

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I had a CT scan of my brain..The results read i had small lucunar infarct left basal ganglia small vessel ischemic disease... What do I have? It started with a headache on my right temple for the last 6 months, doctor sent me to physical theapy, but did

I had a CT scan of my brain..The results read i had small lucunar infarct left basal ganglia small vessel ischemic disease... What do I have?  It started with a headache on my right temple for the last 6 months,  doctor sent me to physical theapy, but did

Small strokes: A small lacunar infarct refers to a stroke from occlusion of a small blood vessel. Small vessel ischemic disease refers to a chronic process whereby the small blood vessels become smaller and smaller over time and cause tiny strokes in certain brain tissues. Typical risk factors are chronic hypertension, smoking and diabetes mellitus. These small strokes can be significant when they accumulate. ...Read more

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Two MRIs both have shown "mild amount of signal hyperintensity in the periventricular white matter bilaterally." What could this mean?

 Two MRIs both have shown "mild amount of signal hyperintensity in the periventricular white matter bilaterally." What could this mean?

The description: is not very specific, and in the absence of clinical context, it is difficult to assess the significance. Most likely it is an incidental finding of little concern, but talk to your doctor about it. ...Read more

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What does scattered foci off adnormal t/2 flair hyperintensity within the periventricular white matter? Mri was ordered for MS symptoms

What does scattered foci off adnormal t/2 flair hyperintensity within the periventricular white matter? Mri was ordered for MS symptoms

Maybe diagnostic: Your doctor needs to counsel you about this result, as one explanation could well be MS, but other causes may be considered. Have a neurologist fully confirm or disconfirm the diagnosis ASAP. ...Read more

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I was detected to have a chronic lacunar infarct, left parietal periventricular white matter. Please advise what it is and if it is fatal. ?

Sign of a stroke: Such a term implies there is evident of an old stroke (size matters) on the left side of the brain in ther deeper area beneath the surface. Periventrical lesions there are common for small strokes often associated with hypertension/diabetes - it obviously was not be fatal in itself, but the underlying disease must be managed medically. The effects may best be measured by neuropsych. ...Read more

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53 yo female (RN) s/p optic neuritis. MRI shows "FLAIR & T2 images show scattered punctate areas of increased signal w/I periventricular white matter"?

53 yo female (RN) s/p optic neuritis. MRI shows "FLAIR & T2 images show scattered punctate areas of increased signal w/I periventricular white matter"?

MS or not MS?: This kind of case will either be diagnosed as optic neuritis or as MS. Since the T2 / FLAIR lesions are small (i.e. punctate) it is a bit uncertain. If they were a bit larger, the diagnosis would be MS. For smaller lesions, perhaps it is not. A spinal tap may help to sort out the answer. The answer is important, so that future relapses can be prevented. Think about vitamin D. ...Read more

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What is mild chronic ischemic changes in bilateral frontal periventricular white matter?

What is mild chronic ischemic changes in bilateral frontal periventricular white matter?

Nonspecific WM: Nonspecific periventricular white matter changes- These are normally small spots without clinical relevance. They are more common for people with high blood pressure, diabetes, head injuries or in people who smoke. They do not have a defined clinical meaning. ...Read more

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I am 35 female MRI states Punctate increased FLAIR signal foci in the periventricular white matter bilaterally.

I am 35  female MRI states  Punctate increased FLAIR signal foci in the periventricular white matter bilaterally.

ABNORMAL MRI: The abnormal MRI may have a variety of causes, Migraine Headaches, HTN, Diabetes. Depending on your symptoms , Full lab work including evaluation for Lyme disease / VIT d deficiency/ b12 folic acid /thyroid studies/ Sjogrens Syndrome and Sarcoid evaluations. Also potentially a clotting work up. Follow up with your Internist and Neurology Consult ...Read more

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I AM 43 MRI STATES SEVERAL NON SPECIFIC PUNCTATE PERIVENTRICULAR WHITE MATTER AND SUBCORTIAL SIGNAL HYPERSENSITIVITIES. ALSO INFERIOR DIPLACEMENT ?

I AM 43 MRI STATES SEVERAL NON SPECIFIC PUNCTATE PERIVENTRICULAR WHITE MATTER AND SUBCORTIAL SIGNAL  HYPERSENSITIVITIES. ALSO INFERIOR DIPLACEMENT ?

Not to worry : These white spots are seen very commonly and tend to increase with age. Inferior displacement of what? I presume they refer to the cerebellum tonsils. Mildly lower is the way they developed. If they fall below a certain level then they are called a chiari malformation but that is not what this sounds like. ...Read more

Basal Ganglia (Definition)

This is the term for several areas of the brain that work together as a functional unit: the striatum (caudate and putamen), the globus pallidus, the substantia nigra, and the subthalamic nucleus. The most well known function of the basal ganglia is voluntary motor control, but it is also involved in development of routine behaviors; eye movements; and ...Read more


Dr. Dariush Saghafi
1,848 doctors shared insights

Migraine (Definition)

A type of headache that is associated with throbbing localized pain and usually causes light ...Read more