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Doctor insights on: Atypical Migraines Lupus Periventricular White Matter Basal Ganglia

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My mother, 84, MRI scan> subacute infarcts, bilateral frontal lobes, small vessel ischematic changes inthe basal ganglia, periventricular white matter?

My mother, 84, MRI scan> subacute infarcts, bilateral frontal lobes, small vessel ischematic changes inthe basal ganglia, periventricular white matter?

Small vessel disease: Mri in a 84 years old lady showing infarcts and small vessel disease means she is having ministrokes. That is very common in that age group. If she has heart disease or carotid artery disease or risk factors like high BP or diabetes or high lipids they should be controlled and she should follow up with her dr who can give her further recommendations. ...Read more

White Matter (Definition)

White matter is one of the two components of the central nervous system and consists of glial cells and myelinated axons that transmit signals from one region of the cerebrum to another and between the cerebrum and lower brain centers. White matter tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid ...Read more


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Had a MRI brain scan.Report says prominent virchow-robin spaces in fronto-parietal white matter and basal ganglia.No other abnormality, is this normal?

Had a MRI brain scan.Report says prominent virchow-robin spaces in fronto-parietal white matter and basal ganglia.No other abnormality, is this normal?

Yes: The virchow-robin spaces are peri vascular spaces normally seen around blood vessels and are not associated with any central nervous system pathology. Please try not to worry as the report you cite is fine. Well wishes. ...Read more

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53 yo female (RN) s/p optic neuritis. MRI shows "FLAIR & T2 images show scattered punctate areas of increased signal w/I periventricular white matter"?

53 yo female (RN) s/p optic neuritis. MRI shows "FLAIR & T2 images show scattered punctate areas of increased signal w/I periventricular white matter"?

MS or not MS?: This kind of case will either be diagnosed as optic neuritis or as MS. Since the T2 / FLAIR lesions are small (i.e. punctate) it is a bit uncertain. If they were a bit larger, the diagnosis would be MS. For smaller lesions, perhaps it is not. A spinal tap may help to sort out the answer. The answer is important, so that future relapses can be prevented. Think about vitamin D. ...Read more

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Two MRIs both have shown "mild amount of signal hyperintensity in the periventricular white matter bilaterally." What could this mean?

 Two MRIs both have shown "mild amount of signal hyperintensity in the periventricular white matter bilaterally." What could this mean?

The description: is not very specific, and in the absence of clinical context, it is difficult to assess the significance. Most likely it is an incidental finding of little concern, but talk to your doctor about it. ...Read more

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What does scattered foci off adnormal t/2 flair hyperintensity within the periventricular white matter? Mri was ordered for MS symptoms

What does scattered foci off adnormal t/2 flair hyperintensity within the periventricular white matter? Mri was ordered for MS symptoms

Maybe diagnostic: Your doctor needs to counsel you about this result, as one explanation could well be MS, but other causes may be considered. Have a neurologist fully confirm or disconfirm the diagnosis ASAP. ...Read more

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I was detected to have a chronic lacunar infarct, left parietal periventricular white matter. Please advise what it is and if it is fatal. ?

Sign of a stroke: Such a term implies there is evident of an old stroke (size matters) on the left side of the brain in ther deeper area beneath the surface. Periventrical lesions there are common for small strokes often associated with hypertension/diabetes - it obviously was not be fatal in itself, but the underlying disease must be managed medically. The effects may best be measured by neuropsych. ...Read more

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What is mild chronic ischemic changes in bilateral frontal periventricular white matter?

What is mild chronic ischemic changes in bilateral frontal periventricular white matter?

Nonspecific WM: Nonspecific periventricular white matter changes- These are normally small spots without clinical relevance. They are more common for people with high blood pressure, diabetes, head injuries or in people who smoke. They do not have a defined clinical meaning. ...Read more

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I am 35 female MRI states Punctate increased FLAIR signal foci in the periventricular white matter bilaterally.

I am 35  female MRI states  Punctate increased FLAIR signal foci in the periventricular white matter bilaterally.

ABNORMAL MRI: The abnormal MRI may have a variety of causes, Migraine Headaches, HTN, Diabetes. Depending on your symptoms , Full lab work including evaluation for Lyme disease / VIT d deficiency/ b12 folic acid /thyroid studies/ Sjogrens Syndrome and Sarcoid evaluations. Also potentially a clotting work up. Follow up with your Internist and Neurology Consult ...Read more

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I AM 43 MRI STATES SEVERAL NON SPECIFIC PUNCTATE PERIVENTRICULAR WHITE MATTER AND SUBCORTIAL SIGNAL HYPERSENSITIVITIES. ALSO INFERIOR DIPLACEMENT ?

I AM 43 MRI STATES SEVERAL NON SPECIFIC PUNCTATE PERIVENTRICULAR WHITE MATTER AND SUBCORTIAL SIGNAL  HYPERSENSITIVITIES. ALSO INFERIOR DIPLACEMENT ?

Not to worry : These white spots are seen very commonly and tend to increase with age. Inferior displacement of what? I presume they refer to the cerebellum tonsils. Mildly lower is the way they developed. If they fall below a certain level then they are called a chiari malformation but that is not what this sounds like. ...Read more

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I have been having MS symptoms for a while. Just got back my MRI and it says I have a 5mm lesion right frontal periventricular white matter. Ms possib

I have been having MS symptoms for a while. Just got back my MRI and it says I have a 5mm lesion right frontal periventricular white matter. Ms possib

Other thoughts: One 5 mm lesion does not fulfill mcdonald's criteria which was designed to define those individuals who are likely to develop ms by mri. Your doctor would probably want further testing including veps (visual evoked potentials), oct (optical coherence tomography), mris of the spine, labs, and possibly a lumbar puncture. Good luck and well wishes. ...Read more

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Basal Ganglia (Definition)

This is the term for several areas of the brain that work together as a functional unit: the striatum (caudate and putamen), the globus pallidus, the substantia nigra, and the subthalamic nucleus. The most well known function of the basal ganglia is voluntary motor control, but it is also involved in development of routine behaviors; eye movements; and ...Read more


Dr. Dariush Saghafi
1,802 doctors shared insights

Migraine (Definition)

A migraine is a type of headache that is associated with throbbing localized pain. It also usually causes light sensitivity, nausea, and vomiting. Migraines can ...Read more