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Doctor insights on: Atypical Lobular Hyperplasia Of Breast

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With a previous diagnosis of atypical lobular hyperplasia, is it wiser to terminate a pregnancy at age 49 to avoid increase breast cancer risk?

With a previous diagnosis of atypical lobular hyperplasia, is it wiser to terminate a pregnancy at age 49 to avoid increase breast cancer risk?

No simple answer: This question is too complex to answer in this format--please see a breast surgeon to discuss. Population studies note a higher risk of breast cancer just after pregnancies, likely related to women who have existing (hormone-sensitive) cancers in their breast during pregnancy. Also, first pregnancies late in life are associated w/increase breast ca risk. How this might affect you is hard to know. ...Read more

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What exactly is atypical hyperplasia of the breast?

What exactly is atypical hyperplasia of the breast?

Irregular Cells: Atypical hyperplasia (ah) is the term used to describe the development of abnormal cells in the breast. These cells may originate from the breast ducts (atypical ductal hyperplasia) or the lobules (atypical lobular hyperplasia). Ah is not cancer, but it increases the risk of developing breast cancer. Therefore patients with a diagnosis of ah often require more frequent breast cancer screening. ...Read more

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What is atypical hyperplasia of the breast? What symptoms do you get?

What is atypical hyperplasia of the breast? What symptoms do you get?

See below: Atypcal hyperplasia can be a marker of pre-cancerous changes of the breast. A person with this finding may need a surgical biopsy to remove a portion of the breast tissue to be sure all is benign, or close monitoring. There would be no symptoms from this condition, and likely no breast lump associated with it either. http://www.mayoclinic.com/health/atypical-hyperplasia/ds01018\p. ...Read more

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How do you usually treat atypical hyperplasia in a breast biopsy?

How do you usually treat atypical hyperplasia in a breast biopsy?

Depends .: If the biopsy was a needle/core biopsy, most would surgically excise. There is a small (approximately 20%) chance of finding dcis at excision. Once excised, most patients are considered 'high risk'. These patients may benefit from chemoprevention (tamoxifen) and/or yearly mri. To further assess one's risk, they should see a breast professional. ...Read more

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I had surgical breast biopsy then atypical hyperplasia removal. Was this necessary? What would have happened if i hadn't intervened?

I had surgical breast biopsy then atypical hyperplasia removal. Was this necessary? What would have happened if i hadn't intervened?

Hard to know: You apparently had a breast mass or an imaging abnormality. It was not feasible to know the nature of the lesion without removing and examination by a pathologist. If is good that it was not cancer. ...Read more

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What percentage of atypical hyperplasia becomes breast cancer?

What percentage of atypical hyperplasia becomes breast cancer?

Small percentage: In a recent study in the annals of surgical oncology, they looked at how many surgical excisions performed for atypical hyperplasia displayed either dcis or cancer. Out of the cases that the study reviewed, only about 1% of the cases upstaged to either dcis or cancer. ...Read more

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I have lobular neoplasia. Is it a likely that i will develop breast cancer in the future?

I have lobular neoplasia. Is it a likely that i will develop breast cancer in the future?

Sightly increased...: There is a slightly increased risk of breast cancer with lobular neoplasia, but the majority of women with this diagnosis do not get breast cancer. Some sites describe a 7 to 11 times increased risk for future breast cancer. Tamoxifen may be a consideration for breast cancer prevention. See a breast specialist and consider genetic testing for breast cancer risk analysis. ...Read more

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Can someone with lobular carcinoma breast feed?

Can someone with lobular carcinoma breast feed?

After treatment: I trust that you have been treated for the carcinoma. If you have been treated it is okay to breast feed. ...Read more

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What is the survival rate for a 46 yr old pt with stage 2B invasive lobular breast cancer w/node involvement?

What is the survival rate for a 46 yr old pt with stage 2B invasive lobular breast cancer w/node involvement?

Approximately 80%: The exact answer to this question depends on a number of factors: actual tumor size, level of estrogen expression, number of nodes involved, medications given and individual response to medications. Lifestyle factors are also key. 80% 5-year survival comes from pooled data from a variety of patients. It's best to ask you medical oncologist to calculate your survival based upon your personal data ...Read more

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What is the survival rate for a 46 yr old pt with stage 2B invasive lobular breast cancer w/node involvement?

What is the survival rate for a 46 yr old pt with stage 2B invasive lobular breast cancer w/node involvement?

Better than 85%: Invasive lobular carcinoma begins in the milk-producing glands (lobules) of the breast the cells having broken out of the lobule where they began and in Stage IIB have spread to regional lymph nodes. It typically doesn't form a lump, but often causes a fullness in one part of the breast.. They tend to have more hormone-receptor–positive tumors , lower nuclear grade and survival better than 85% ...Read more

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Can women with invasive lobular carcinoma breast feed their babies?

Can women with invasive lobular carcinoma breast feed their babies?

Yes: Breast cancer cannot be transmitted to your baby in breast milk you are better off to treat your cancer sooner rather than continuing to breast feed your baby. ...Read more

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Is it safe for a women with invasive lobular carcinoma breast feed?

Is it safe for a women with invasive lobular carcinoma breast feed?

Yes: I trust that you were treated for breast carcinoma and are now blessed with a child. Cancer is not transmitted through milk, though some other diseases, such as HIV can be. ...Read more

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Grandma had lobular BC, worried that I have it. Thickening in breast tissue and pain for 5 mths. Mammogram and ultrasound fine. Should I get MRI?

Grandma had lobular BC, worried that I have it. Thickening in breast tissue and pain for 5 mths. Mammogram and ultrasound fine.  Should I get MRI?

Risk: Pain needs to be addressed. Family history is important but do not necessarily indicate you inherited risk. You may consider genetic testing for BRCA especially if any other direct family members has Breast CA ...Read more

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How do doctors know when is chemotherapy needed for ductal and lobular breast cancer?

How do doctors know when is chemotherapy needed for ductal and lobular breast cancer?

Depends: Depends on the stage of the disease, cell type, size of cancer, whether lymph nodes are involved, hormone receptors, dna oncotype testing, etc. Many decades of research helps the medical oncologisr discuss with the patient their options & choices. ...Read more

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My mom had invasive lobular breast cancer. Is that more hereditary than invasive ductal?

My mom had invasive lobular breast cancer. Is that more hereditary than invasive ductal?

Probably no, but...: Most of the statistics I have seen show similar rates of lobular cancer in carriers of BRCA 1/2 mutations (which is the most common recognizable inherited breast cancer trait) compared to non-carriers. Exception: carriers of CDH1 mutations (hereditary diffuse gastric cancer syndrome) have high risk for aggressive stomach cancer and lobular breast cancer. ...Read more

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My mom had lobular breast cancer at 54 and her paternal cousin had breast cancer at 48. Everyone is brca negative. Is this likely hereditary?

My mom had lobular breast cancer at 54 and her paternal cousin had breast cancer at 48. Everyone is brca negative. Is this likely hereditary?

Hard to tell...: ...without more info. BRCA 1 and 2 are not the only genes known to increase the risk for cancer and there are probably others we do not know anything about. Someone in the family (preferably your mom or her cousin) should visit a genetic counselor (if they have not yet done so) to see what other genes need to be tested if necessary and what else they can do to reduce their risk. ...Read more

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My mom was diagnosis with tubulo-lobular breast cancer nottingham score grade 2. Tubule formation was graded 3, with very little tubules . How can this be.?

My mom was diagnosis with tubulo-lobular breast cancer nottingham score grade 2. Tubule formation was graded 3, with very little tubules . How can this be.?

Mostly lobular: If the tumor is mostly lobular with very little tubule formation it would be graded 3 in terms of tubule formation. The overall grade would still be 2 since the nuclei are usually small sized and the mitotic rate low. These tumors usually have a good prognosis if they are under 2cm and a single focus. ...Read more

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