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Doctor insights on: Atypical Glandular Cells Of Undetermined Significance

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Pap was not normal Endocervical/transformation zone component present. Atypical squamous cells of undetermined significance asc-us What is this cancer?

Pap was not normal Endocervical/transformation zone component present. Atypical squamous cells of undetermined significance asc-us What is this cancer?

Not likely: It's a fairly common finding on Pap smear. It would rarely indicate cancer. Sometimes it means precancerous changes, which are not serious. Needs further evaluation. ...Read more

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What do these biopsy results of thyroid nodule mean ATYPIA OF UNDETERMINED SIGNIFICANCE OR FOLLICULAR LESION OF UNDETERMINED SIGNIFICANCE?

Re-FNA in 3-6 Months: Hi Jami, AUS/FLUS is a term that cytopathologists use for thyroid nodules that they basically are "unsure" about. Classic management for this diagnosis is to have a second repeat FNA in 3-6months. Nowadays though high tech molecular pathology tests can sometimes divide AUS/FLUS definitively into benign and malignant categories. Please setup a virtual consult with me for more information. ...Read more

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What's monoclonal lymphocytes of undetermined significance?

What's monoclonal lymphocytes of undetermined significance?

Excellent question.: Monoclonal lymphocytes mean that a single lymphocyte has been stimulated to divide and create an expanded number of identical daughter cells. There are enough of them to be identified by a test (flow cytometry) but not enough to meet criteria for a leukemia. There may be a genetic predisposition. This is a benign condition, but there is uncertainty as to whether it might progress to malignancy. ...Read more

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My pap smear and my results were endocervical/transformation zone component atypical squamous cells of undetermined significance?

My pap smear and my results were  endocervical/transformation zone component atypical squamous cells of  undetermined significance?

Follow up needed: You should discuss follow up with your doctor. Typically a colposcopy is recommended to look closer at your cervix. ...Read more

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If pap smear is abnormal, atypical squamous cells of undetermined endocervical/squamous metaplastic cells are present. + HPV is positive. I worry?

If pap smear is abnormal, atypical squamous cells of undetermined endocervical/squamous metaplastic cells are present. + HPV is positive. I worry?

Probably not: This is a common finding on a pap smear and is slightly abnormal. It is not likely to be anything dangerous. However, the only way to be sure is to be evaluated by your doctor. Most times an exam called a colposcopy is recommended in the office. Hope this helps. ...Read more

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Biospy of neck nodule report atypical lymphoid proliferation. What does this means?

Biospy of neck nodule report atypical lymphoid proliferation. What does this means?

Uncertain results: There are several reasons for a result in the grey zone of certainty such as this. One is time course of disease (may be harder to detect early on); one is a mixture of normal and abnormal such as a node near an involved node; one is a variant of a known disease, or an unknown disease, and the last is a pathologist who is cautious or inexperienced with the disease or tissue. Wait, 2nd opin, or bx ...Read more

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Endocervix exhibiting papillary hyperplasia with severe lymphoplasmatic infiltrate in the stroma.No transformation zone.what does this mean. Benign.

Endocervix exhibiting papillary hyperplasia with severe lymphoplasmatic infiltrate in the stroma.No transformation zone.what does this mean.
Benign.

Pathology report: You have to go over the details with your doc. The most important word was the last word that you typed which said that the lesion was BENIGN. Not malignant. That is the key but go over it with your doc. ...Read more

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Pap results indicate "Rare metaplastic cells identified" What is the significance of this?

Pap results indicate "Rare metaplastic cells identified"  What is the significance of this?

Not much: Unless otherwise noted, these are benign cells in the endocervix that have undergone a change that's often related to HPV but is of no great consequence. Continue following the recommended protocols. If there are other abnormalities on the smear, get them addressed. ...Read more

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Hi Doctor, what it means small fragment of squamous cells with dysplasia, benign endocervical cells present. Thanks?

Hi Doctor, what it means small fragment of squamous cells with dysplasia, benign endocervical cells present. Thanks?

Pap: you need to have your pap test repeated in 3 months to see if has reverted to normal, by in itself cells with dysplasia only means that you may have had a past infection or may have HPV ...Read more

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Atypical endocervical glandular cells favor neoplasty on recent pap. What does this mean?

This is serious : You have cancer until proved otherwise. I hope you do not. If you do, I hope you caught it awhile it is curable. You must follow up ...Read more

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Weakly prolif. Endo. W foci of stromal and glandular breakdown. Rare lymphoid aggregates found in portions of biopsy in context to myxoid stroma seen ?

Weakly prolif. Endo. W foci of stromal and glandular breakdown. Rare lymphoid aggregates found in portions of biopsy in context to myxoid stroma seen ?

No ovulation: This is a description of endometrium that has been in the proliferative (growing or recovery) phase for too long. That is the phase which normally preceeds ovulation. After ovulation, the endometrium moves into the secretory phase during which an embryo can be received if pregnancy takes place; otherwise a normal menstrual phase (period) begins. Hormonal treatment may be necessary if out of order. ...Read more

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Epithelial cell abnormalties atypical aglandular cells nos. What does this mean from my pap?

Epithelial cell abnormalties atypical aglandular cells nos.  What does this mean from my pap?

Atypical Glandular cells: The cervix has two cell types- squamous, and glandular. Most abnormalities are in the squamous cells, and can often be seen with colposcopy. Glandular abnormalities are usually not visible with a magnifying lens at colposcopy, and so biopsies are needed to rule out cancers. Glandular cancers are related to HPV usually like the squamous ones, so HPV testing can also help. ...Read more

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Please explain pap results: "rare hyperchromatic groups of atypical glandular cells, favor endocervical". What could this mean?

Please explain pap results: "rare hyperchromatic groups of atypical glandular cells, favor endocervical". What could this mean?

Colpo: The cells are appearing atypical. So there is suspicion that there could be precancerous or cancerous cells present. Depending on your HPV status your doc most likely will want you to do a colposcopy. ...Read more

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Benign endocervical tissue showing immature squamous metaplasia, what is that?

Benign endocervical tissue showing immature squamous metaplasia, what is that?

ask yiour Gynecologi: The doctor who did the test can explain it better. But basically the test is looking for cancer cells which your report says you do not have at the present time. But continue to follow with annual pap tests so that this abnormalityy(minimal abnormality) resolves or gets monitored for any worsening. It is all a very slow process, not of any immediate concern but not always predictable. ...Read more

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Epithelial cell abnormality, High-Grade Squamous Intraephithelial lesion, atypical glandular cells and sever dysplasia. What should my concern be?

Epithelial cell abnormality, High-Grade Squamous Intraephithelial lesion, atypical glandular cells and sever dysplasia.  What should my concern be?

Pap smear: Is this the result of your pap smear? if yes, then it means moderate or severe cervical intraepithelial neoplasia or carcinoma in situ, which in some cases could lead to cervical cancer. you need Colposcopy and possible biopsy. Talk to your Gynecologist regarding a treatment plan. ...Read more

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