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Doctor insights on: Atypical Endometrial Cells On Pap Smear

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Are endometrial cells over 40 normal on a pap smear?

Are endometrial cells over 40 normal on a pap smear?

Not normal: Generally it is considered abnormal when that happens - it should be investigated. ...Read more

Dr. Ed Friedlander
941 Doctors shared insights

Pap Smear (Definition)

A pap smear (cervical smear) is a text looking at the cells from the canal and outside of the cervix to see if any abnormalities (especially ...Read more


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What does it mean to have endometrial cells on a normal pap smear?

Endometrial cells: Within normal limits Pap smear result means that no cell lesions or malignancy have been found. Reactive cellular changes, cellular atrophy, and endometrial cells present are normal variables. Pap smears are an excellent tool, but are not perfect. ...Read more

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I am 45 years old and just has my pap smear as well as an ultrasound last week. Pap and ultra were normal but it came back with endometrial cells.

I am 45 years old and just has my pap smear as well as an ultrasound last week. Pap and ultra were normal but it came back with endometrial cells.

Endometrial cells: I wonder if you mean "endocervical" cells, as those are what we want to see when you have a pap to indicate that there is an adequate sample to rule out issues. Are you sure about them being "endometrial"? ...Read more

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My pap smear was negative for HPV but showed endometrial cells? What does this mean? My dr. Wants to do a biopsy.

My pap smear was negative for HPV but showed endometrial cells? What does this mean? My dr. Wants to do a biopsy.

It's a precaution: Endometrial cells come from your uterus. In women your age, about 12% show normal endometrial cells on their pap smear. Usually they are just normal cells that have "shed" into your pap smear. But about 1 in 10 times they can signal something abnormal is happening in your uterus, possibly cancer. It's recommended that any woman with these cells on a pap smear has further testing, just to be sure. ...Read more

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Had a pap smear on day 10 of menstration. Pap came back normal but shows endometrial cells on uterine lining. What does this mean? Going for a biopsy.

Had a pap smear on day 10 of menstration. Pap came back normal but shows endometrial cells on uterine lining. What does this mean? Going for a biopsy.

Likely okay: Typically, unless a woman is having irregular bleeding, endometrial cells on a pap aren't worrisome at all. That's based on a new recommendation for pap smear management. If you have irregular or heavy bleeding, doctor will want to rule out pre-cancer as cause, hence, biopsy of uterine lining. No harm in biopsy. Your doctor knows you best, so be sure to ask him/her why they have concerns for biops. ...Read more

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I have adenomyosis with heavy bleeding w/clots that soak through my clothes. Pap smear had endometrial cells. Could this be a sign of cancer?

I have adenomyosis with heavy bleeding w/clots that soak through my clothes. Pap smear had endometrial cells. Could this be a sign of cancer?

Not cancer: Endometrial cells on pap is not a sign of cancer. Adenomyosis can explain heavy bleeding and cramping, but doesn't rule out cancer. Make certain your concerns and communication with your doctor is very good. ...Read more

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Is it normal to see endometrial tissue on a pap smear right after period ends?

Is it normal to see endometrial tissue on a pap smear right after period ends?

It is normal, howeve: Exfoliated endometrial cells are commonly seen in specimens, obtained during the proliferative phase of the menstrual cycle. However, endometrial cells have been considered a potential harbinger of endometrial adenocarcinoma when seen in cervical/vaginal cytology preparations of postmenopausal woman.
In a woman 40 years old or older endometrial cells should be reported and follow up need. ...Read more

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If I had any cervical/endometrial polyps would they have been easily noticed during my routine Pap smear recently?

If I had any cervical/endometrial polyps would they have been easily noticed during my routine Pap smear recently?

Not endometrial: Cervical polyps may be visible but endometrial polyps would not be. Even cervical polyps would not be obvious if the lesion is in the canal and not projecting outside.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex.
Get HPV vaccine. ...Read more

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Does it matter in what order you schedule an endometrial biopsy, a pap smear and an ultrasound for postmenoposal bleeding - or timing between them?

Does it matter in what order you schedule an endometrial biopsy, a pap smear and an ultrasound for postmenoposal bleeding - or timing between them?

Probably not: Though your doctor would most likely do the pap smear and endometrial biopsy at the same time, and in the office. The ultrasound may be before or after, and may be done at your doctors office, or at a hospital or imaging center. ...Read more

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Pelvic ultrasound shows thickness of lining to be 26mm. I am postmenopausal. Endometrial biopsy also pap smear negative I am obese. Worried

Postmenopausal bleed: The next recommendation is likely an endometrial biopsy. What was the indication for the ultrasound. Concerned rather than worried. The bottom line is to rule out endometrial cancer, especially if you have post menopausal bleeding. ...Read more

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My pap smear and my results were endocervical/transformation zone component atypical squamous cells of undetermined significance?

My pap smear and my results were endocervical/transformation zone component atypical squamous cells of undetermined significance?

Follow up needed: You should discuss follow up with your doctor. Typically a colposcopy is recommended to look closer at your cervix. ...Read more

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Following pap smear I need to have a colposcopic examination with biopsy and 'atypical spindle cell tumour needs to be excluded'. What is this?

Following pap smear I need to have a colposcopic examination with biopsy and 'atypical spindle cell tumour needs to be excluded'. What is this?

ASCUS: The preferred approach for evaluation of women ages 25 or older with ASC-US cytology is testing for high-risk types of HPV with triage of women who test positive to colposcopy. Use of HPV testing to triage further evaluation of ASC-US is the most effective strategy for detecting high-grade premalignant disease or cervical cancer. ...Read more

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Pap Smear done 8 months back, no atypical cells, only mild inflammatory smear. Doctor said it is normal, should the test be repeated any time soo?

Pap Smear done 8 months back, no atypical cells, only mild inflammatory smear. Doctor said it is normal, should the test be repeated any time soo?

No. Not needed.: It's good news if the cells where not abnormal. Some inflammatory changes are not worrisome. It is also important to know if the HPV test was done. HPV is a virus which may lead to abnormal cells in time. If not the HPV and cells were both negative, you should have nothing to worry about regarding cervical cancer. Inflammatory changes are usually self limited and may be due to hormonal factors. ...Read more

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If pap smear is abnormal, atypical squamous cells of undetermined endocervical/squamous metaplastic cells are present. + HPV is positive. I worry?

Probably not: This is a common finding on a pap smear and is slightly abnormal. It is not likely to be anything dangerous. However, the only way to be sure is to be evaluated by your doctor. Most times an exam called a colposcopy is recommended in the office. Hope this helps. ...Read more

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Can a pap smear turn out abnormal (atypical epithelial cells, neg hpv) if I just had miscarriage 3 weeks before?

Can a pap smear turn out abnormal (atypical epithelial cells, neg hpv) if I just had miscarriage 3 weeks before?

Yes, . ...: It is no uncommon to have abnormal PAP as reported without detectable HPV. Hence, follow the further advice from your current doctor since s/he knows more about you than anyone on line. ...Read more

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Pap Smear result: A single group of spindle cells admixed with neutrophils is seen representing atypical spindle cell proliferation. Is it cancer?

Pap Smear result: A single group of spindle cells admixed with neutrophils is seen representing atypical spindle cell proliferation. Is it cancer?

No, BUT: Several points. First, you need more than atypical to say it is cancer. They have to look quite abnormal and/or be growing abnormally. HOWEVER, there are reports of groups of atypical spindle cells popping up everywhere due to cancer (lymphoma). That would be cancer. Or growing really fast (cancer).
At a minimum. Watching it Really closely. ...Read more

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Atypical glandular cells - favor neoplastic was my pap smear test result. Negative colposcopy- & endocervical curretings result. Please explain.

Maybe benign and overcall: It is possible that the cells are reactive and they were over called as worrisome for cancer but in fact are completely normal this would explain the findings. You should have me look at the pap smear I will give you the right answer. ...Read more

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Reactive cellular changes associated with inflammation. Atypical endocervical cells seen. On my pap smear result. Am I at risk to cervical cancer?

Reactive cellular changes associated with inflammation. Atypical endocervical cells seen. On my pap smear result. Am I at risk to cervical cancer?

HPV test?: Unfortunately, anyone who has had genital contact is at risk for cervical cancer because the human papilloma virus is so widespread. Usually when we find atypical cells on a pap smear, we reflexively test for hpv. If it is positive, then you do have a small risk for dysplasia or precancer, but if it is negative, you have almost no risk. If your hpv test is (+), you will need follow up. ...Read more

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Will atypical squamous cells (ASCUS) due to chlamydia show up in a Pap smear after only 3 days after sex? Are those cells visible immediately?

Will atypical squamous cells (ASCUS) due to chlamydia show up in a Pap smear after only 3 days after sex? Are those cells visible immediately?

Whoa: ASCUS may be due to HPV, inflammation, or an overcall by a concerned technologist. No one knows how fast they can pop up. There's a protocol for following them up. I'd be surprised if they could develop 3 days after meeting the chlamydia. Treat the infection and repeat the test. Best wishes. ...Read more

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What is an abornomal pap smear with precancerous cells?

A warning: Women with cells that have certain abnormal appearances are much more likely to develop cancer of the cervix or nearby structures. If the area with the cells can be found and removed before it turns cancerous, a life has likely been saved. Before pap smears, cancer of the cervix was a horribly common scourge of young women, as it still is in the poor nations. ...Read more

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What could cells of undetermined significance be on a pap smear?

A number of things: Atypical cells of undetermined significance (ascus) can represent a precancerous condition or may be associated with a variety of benign entities. The diagnosis must be interpreted in relation to other factors, such as the results of hpv testing, if performed. As such, the diagnosis of ascus "pigeon-holes" you into a defined follow up schedule that should be adhered to. ...Read more

Cervical Smear (Definition)

A cervical smear or pap smear is a text looking at cells from the outside and canal of the cervi to see if ...Read more