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Doctor insights on: Atypical Cells Pap Smear

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Dr. Ed Friedlander
926 Doctors shared insights

Pap Smear (Definition)

A pap smear (cervical smear) is a text looking at the cells from the canal and outside of the cervix to see if any abnormalities (especially ...Read more


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My pap smear and my results were endocervical/transformation zone component atypical squamous cells of undetermined significance?

My pap smear and my results were endocervical/transformation zone component atypical squamous cells of undetermined significance?

Follow up needed: You should discuss follow up with your doctor. Typically a colposcopy is recommended to look closer at your cervix. ...Read more

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Following pap smear I need to have a colposcopic examination with biopsy and 'atypical spindle cell tumour needs to be excluded'. What is this?

Following pap smear I need to have a colposcopic examination with biopsy and 'atypical spindle cell tumour needs to be excluded'. What is this?

ASCUS: The preferred approach for evaluation of women ages 25 or older with ASC-US cytology is testing for high-risk types of HPV with triage of women who test positive to colposcopy. Use of HPV testing to triage further evaluation of ASC-US is the most effective strategy for detecting high-grade premalignant disease or cervical cancer. ...Read more

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Pap Smear done 8 months back, no atypical cells, only mild inflammatory smear. Doctor said it is normal, should the test be repeated any time soo?

Pap Smear done 8 months back, no atypical cells, only mild inflammatory smear. Doctor said it is normal, should the test be repeated any time soo?

No. Not needed.: It's good news if the cells where not abnormal. Some inflammatory changes are not worrisome. It is also important to know if the HPV test was done. HPV is a virus which may lead to abnormal cells in time. If not the HPV and cells were both negative, you should have nothing to worry about regarding cervical cancer. Inflammatory changes are usually self limited and may be due to hormonal factors. ...Read more

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If pap smear is abnormal, atypical squamous cells of undetermined endocervical/squamous metaplastic cells are present. + HPV is positive. I worry?

If pap smear is abnormal, atypical squamous cells of undetermined endocervical/squamous metaplastic cells are present. + HPV is positive. I worry?

Probably not: This is a common finding on a pap smear and is slightly abnormal. It is not likely to be anything dangerous. However, the only way to be sure is to be evaluated by your doctor. Most times an exam called a colposcopy is recommended in the office. Hope this helps. ...Read more

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Can a pap smear turn out abnormal (atypical epithelial cells, neg hpv) if I just had miscarriage 3 weeks before?

Can a pap smear turn out abnormal (atypical epithelial cells, neg hpv) if I just had miscarriage 3 weeks before?

Yes, . ...: It is no uncommon to have abnormal PAP as reported without detectable HPV. Hence, follow the further advice from your current doctor since s/he knows more about you than anyone on line. ...Read more

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Pap Smear result: A single group of spindle cells admixed with neutrophils is seen representing atypical spindle cell proliferation. Is it cancer?

Pap Smear result: A single group of spindle cells admixed with neutrophils is seen representing atypical spindle cell proliferation. Is it cancer?

No, BUT: Several points. First, you need more than atypical to say it is cancer. They have to look quite abnormal and/or be growing abnormally. HOWEVER, there are reports of groups of atypical spindle cells popping up everywhere due to cancer (lymphoma). That would be cancer. Or growing really fast (cancer).
At a minimum. Watching it Really closely. ...Read more

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Atypical glandular cells - favor neoplastic was my pap smear test result. Negative colposcopy- & endocervical curretings result. Please explain.

Maybe benign and overcall: It is possible that the cells are reactive and they were over called as worrisome for cancer but in fact are completely normal this would explain the findings. You should have me look at the pap smear I will give you the right answer. ...Read more

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Reactive cellular changes associated with inflammation. Atypical endocervical cells seen. On my pap smear result. Am I at risk to cervical cancer?

Reactive cellular changes associated with inflammation. Atypical endocervical cells seen. On my pap smear result. Am I at risk to cervical cancer?

HPV test?: Unfortunately, anyone who has had genital contact is at risk for cervical cancer because the human papilloma virus is so widespread. Usually when we find atypical cells on a pap smear, we reflexively test for hpv. If it is positive, then you do have a small risk for dysplasia or precancer, but if it is negative, you have almost no risk. If your hpv test is (+), you will need follow up. ...Read more

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Will atypical squamous cells (ASCUS) due to chlamydia show up in a Pap smear after only 3 days after sex? Are those cells visible immediately?

Will atypical squamous cells (ASCUS) due to chlamydia show up in a Pap smear after only 3 days after sex? Are those cells visible immediately?

Whoa: ASCUS may be due to HPV, inflammation, or an overcall by a concerned technologist. No one knows how fast they can pop up. There's a protocol for following them up. I'd be surprised if they could develop 3 days after meeting the chlamydia. Treat the infection and repeat the test. Best wishes. ...Read more

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How often can I need a pap smear after abnormal cells?

Depends on the type: And severity of abnormality. Mild dysplasia requires yearly repeat paps. Other types of abnormalities may require colposcopic examination, with or without biopsy. It would be prudent to follow your doctor's advice. ...Read more

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What is an abornomal pap smear with precancerous cells?

A warning: Women with cells that have certain abnormal appearances are much more likely to develop cancer of the cervix or nearby structures. If the area with the cells can be found and removed before it turns cancerous, a life has likely been saved. Before pap smears, cancer of the cervix was a horribly common scourge of young women, as it still is in the poor nations. ...Read more

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What does abnormal cells mean in a pap smear examination result?

What does abnormal cells mean in a pap smear examination result?

Abnormal PAP: We do pap smears to screen for cervical cancer cells. The pap smear has helped us reduce cervical cancer to very small numbers. We think that cancer forms in stages over many years (about 10-15). The cells get progressively abnormal before they become cancerous and this is the opportunity that the pap smear gives us. Remove/kill the abnormal cells before cancer develops. ...Read more

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What could cells of undetermined significance be on a pap smear?

A number of things: Atypical cells of undetermined significance (ascus) can represent a precancerous condition or may be associated with a variety of benign entities. The diagnosis must be interpreted in relation to other factors, such as the results of hpv testing, if performed. As such, the diagnosis of ascus "pigeon-holes" you into a defined follow up schedule that should be adhered to. ...Read more

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Pap smear came back with abnormal cells. What does this indicate?

Pap smear came back with abnormal cells. What does this indicate?

Common: That is relatively common, we would need to know how abnormal. Some could be due to inflammation, some to hpv involvement, and others to tumors. ...Read more

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What does it mean if you have precancerous cells on your pap smear?

What does it mean if you have precancerous cells on your pap smear?

At risk of cancer: Precancerous cells indicate presence of pathologic processes that could lead to development of cancer. ...Read more

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After having a pap smear I was told I had abnormal cells. Can anyone explain this to me in more detail?

After having a pap smear I was told I had abnormal cells. Can anyone explain this to me in more detail?

ASCUS: Abnormal cells in pap smears = atypical squamous cells of undetermined significance (ascus). This means that there are some "funny looking" cells that are not otherwise classifiable. Usually your doctor will recommend some sort of follow up including a repeat pap smear and/or colposcopy if this particular finding keeps recurring. ...Read more

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Cervical Smear (Definition)

A cervical smear or pap smear is a text looking at cells from the outside and canal of the cervi to see if ...Read more