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Doctor insights on: Atypical Cells In Thyroid Nodule

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What is rare histiocytes and follicular cells in thyroid nodule?

What is rare histiocytes and follicular cells in thyroid nodule?

Incomplete informat: The presence of histiocytes (a type of inflammatory cell) & expected follicular cells in thyroid is not necessarily worrisome. But it depends on your symptoms, & what prompted the biopsy / FNA to begin with. Also, did you have a radioactive iodine exam? (Called "thyroid uptake & scan")? That tells you if the follicle is "functional" or not (making hormone). A hyperfunctional nodule is more worriso ...Read more

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Nodule (Definition)

Any growth or deposit in the body or on its surface may be casually termed a nodule until its character is determined by the familiarity of the physician with it or by the results of a biopsy if it is not so obvious. The term is casual ...Read more


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What is "rare epithelioid giant cells" in fna of thyroid nodules?

What is "rare epithelioid giant cells" in fna of thyroid nodules?

Review with your MD: Usually, when one aspirates a thyroid cyst one may see "rare epithelioid giant cells". Most simple cysts of the thyroid are benign. However, fine needle aspirate of cystic papillary thyroid carcinoma may also show this feature and may lack diagnostic cells. So, additional information is needed to interpret the cytology report. ...Read more

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Can a "normal" thyroid nodule develop abnormal follicular neoplasm cells over time?

Possibly: Ghe tendency for transformation of a nodule in the thyroid gland depends on whether the nodule is solitary or multiple. The latter for the most part is a goiter and rarely if ever associated with Ca of thyroid. A solitary nodule has to be examined as to being hot or cold. If hot and functional Ca essentially doesn't occur. If the solitary nodule cold, there is a 30% chance of converting to Ca. ...Read more

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Thyroid nodule came back negative but cells are suspicious for hurthle cell neoplasm. What does that mean?

Thyroid nodule came back negative but cells are suspicious for hurthle cell neoplasm. What does that mean?

Surgical biopsy: Hi. Going just on what you've told us, you probably need a surgical biopsy. A Hurthle cell neoplasm can be either benign or cancer, and the cytopathology often cannot make the distinction. Therefore, to exclude or confirm cancer will require a surgical biopsy. But I don't have the data. Your doc will tell you what's needed. Good luck! ...Read more

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Fnac report of thyroid nodule-colloid, individual follicular cell n folliculr cell in cluster in haemorrhagic bckground. What it indicate?

Nothing: Reports states the nodule was benign which means not cancerous, hemorrhagic, there was some blood which was probably from the size of needle used so don't worry. ...Read more

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Repeated thyroid nodule biopsy cold solid 3x7cm. How could he not get enough cells with such a large nodule? Also 2.4cm cold follicularGenetic testing

Possible: May be if nodule has fluid ( Cyst ) may not get cells ( how many times was done ? more than twice is unusual ) . If strongly suspicious for malignancy an image guided core needle biopsy , or even removal ( surgery ) Discuss with your doctor , plan of treatment Do not ignore if necessary take second opinion . ...Read more

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FNA 2.5 cm solid thyroid nodule was FLUS and not enough cells for Thyroseq. Second FNA was non diagnostic and not enough cells for thyroseq. What now?

Seek second opinion: Go to an endocrinologist for further guidance. He/she may find you someone expert in doing ultrasound guided biopsy. Alternatively this nodule can be removed surgically and that will resolve the problem permanently. ...Read more

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I recently had a FNA of my thyroid nodule. The results showed "benign, hyperplastic nodule with extensive Hurthle cell metaplasia". Should I worry?

I recently had a FNA of my thyroid nodule. The results showed "benign, hyperplastic nodule with extensive Hurthle cell metaplasia".  Should I worry?

Needs surgery: see your doctor. You need a referral to a surgeon. Hurtle cell can be benign or malignant. It is impossible to tell whether it is benign or cancerous on a fine needle aspiration. You need surgery to remove that side of your thyroid in order to know100% if it is one or the other. ...Read more

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Thyroid nodule with rare cluster ofoverlapping enlarged cells, grooves and pale chromatin. Rebiopsy or surgery? 2.9x1.1x2.2 cm

Thyroid nodule with rare cluster ofoverlapping enlarged cells, grooves and pale chromatin. Rebiopsy or surgery? 2.9x1.1x2.2 cm

You have a choice: The results you are sharing are benign. The cells were likely from a fna biopsy. The size of your thyroid nodule meets criteria for removal, greater than 2.5 cm. Okay to talk to your doc and your surgeon about risk/benefits of waiting a few months with repeat ultrasound versus surgery now to remove one side of your thyroid. Good luck. ...Read more

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Doctor called that my SECOND FNA for 2.7cm thyroid nodule was FLUS AGAIN.ThyroseqV2 for SECOND time was blood/too few cells to be diagnostic What now?

Doctor called that my SECOND FNA for 2.7cm thyroid nodule was FLUS AGAIN.ThyroseqV2 for SECOND time was blood/too few cells to be diagnostic What now?

A little confused?: FLUS=follicular lesion of undetermined sig. There have to be cells to make this diag. The usual thing is to redo the US/if nec FNA in a few months, dep on US. If there are cells a Thyroseq.v2 is very accurate for mutations. This sounds non-diagnostic. Make sure doc doing FNA is experienced. Likely need repeat. Ask for pathologist to reread. If 3rd FNA->path look immed to make sure adeq. New doc? ...Read more

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3cm hyperechoic thyroid nodule with increased vascularity, normal TSH fnac- follicular cell with hyperplastic area. What it indicates?

Uncertain: The fna can only help if it shows cancer. But in your case it is ambiguous, so your doctor should guide you what to do next?...What did he/she suggest as the next step? Most doctors would next recommend either surgical excision or monitor closely for some time and see if it is growing in size in which case it has to be taken out. ...Read more

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3cm hypoechoic solid vascular thyroid nodule with a cluster of hurthle cells, fna benign, follow up ultrasound now shows microcalcifications. Cancer?

Not necessarily...: The fact that FNA was reported as benign, the nodule is unlikely to be malignant. Small droplets of benign colloid often mimic "microcalcificatins" of papillary tumor, hence caution is advised. I would suggest repeating the FNA, and consider also collecting samples for gene profiling studies, such as, those manufactured by Veracyte and Asuragen (Note:I have no financial/other interest.) ...Read more

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Went in for followup u/s for left thyroid nodule. Came back as nothing on left but new nodule on right. Worried they got the sides mixed up. Possible?

Went in for followup u/s for left thyroid nodule. Came back as nothing on left but new nodule on right. Worried they got the sides mixed up. Possible?

Not likely: Ultrasound exams are performed by trained technicians and supervised by physicians on site, so a mix up is unlikely. It is, however, common for many people to have multinodular goiter, meaning many cysts on both sides of the gland. These are usually benign & require no further evaluation. If concerned, a needle biopsy can be performed. ...Read more

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How fast do thyroid nodules grow?

Variable: Thyroid nodules are variable in their growth patterns. Some can grow quickly in size, particularly if there is a cystic component to the nodule. Your doctor will usually suggest an ultrasound to follow the growth of the nodule every 6 months to one year, depending on the level of suspicion. ...Read more

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How can I get lid of thyroid nodules?

Hmm: Other than surgery (which I am not necessarily recommending), generally speaking thyroid nodules do not go away. You should have an ultrasound and possibly a needle aspiration. An endocrinologist or head and neck surgeon would be able to help get you worked up. ...Read more

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Can medication shrink thyroid nodules?

Usually not: In the distant past, thyroid hormone was used to 'shrink' nodules. More recent studies with ultrasound monitoring has shown that most nodules do not shrink with thyroid hormone treatment. Because thyroid cancer is the fastest increasing cancer in women, it is important to follow most thyroid nodules with ultrasound. With hashimoto's thyroiditis, there can be false or pseudonodules. ...Read more

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Does medication actually shrink thyroid nodules?

No: There is radioactive therapy for nodules that are hyperactive and secrete hormone or those that are cancerous. Most thyroid nodules are not of these types, and there is no need to shrink them. ...Read more

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Dr. Michael Gabor
13 doctors shared insights

Thyroid (Definition)

The thyroid is an endocrine gland that sits in the lower part of the neck. It produces thyroid hormone - which ...Read more


Dr. Eric Whitman
338 doctors shared insights

Thyroid Nodules (Definition)

Masses in the thyroid that vary in size and should be ...Read more