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Doctor insights on: Atracurium

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Dr. Fred McCurdy
33 doctors shared insights

Atracurium (Overview)

Atracurium is a neuromuscular blocker which is a kind of anesthetic agent.


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When is atracurium used?

When is atracurium used?

Renal failure/insuff: Atracurium is a muscle relaxant which is not dependent on kidney for elimination. So we use it for patients with poor kidney function or failure. ...Read more

Dr. Fred McCurdy
33 doctors shared insights

Atracurium (Overview)

Atracurium is a neuromuscular blocker which is a kind of anesthetic agent.


2

2
When is atracurium used?

Renal failure/insuff: Atracurium is a muscle relaxant which is not dependent on kidney for elimination. So we use it for patients with poor kidney function or failure. ...Read more

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Why atracurium is used in both hepatic and renal failure patients?

Why atracurium is used in both hepatic and renal failure patients?

Atracurium use: The reason atracurium can be used in hepatic and renal failure patients is because the breakdown process is not dependent on kidney are liver function. The drug is broken down through a process called the hoffman eleimination that is independent of organ activity. However, the main metabolite is laudanosine and it can acumulate in elderly renal and liver failure patients. ...Read more

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Why is atracurium used for both hepatic and renal failure patients?

Metabolism: Atracurium is a non-depolarizing neuromuscular blocker. It is metabolized via a process called Hoffmann elimination (ester hydrolysis which is independent of renal, hepatic or enzymatic function). Since you don't need the liver or kidney to metabolize the drug, it is a paralytic often used for patients with renal and/or hepatic failure. ...Read more

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Why atracurium is used in both patients with hepatic and renal failure?

Why atracurium is used in both patients with hepatic and renal failure?

Elimination mechani: Atracurium is not dependent on liver or kidneys for elimination, so it wears off normally in these patients. ...Read more

Dr. Debra Rosenblatt
2 doctors shared insights

Tracrium (Definition)

Tracrium is a neuromuscular blocker which is a ...Read more