Doctor insights on:
Atorvastatin Vs Simvastatin Side Effects
Atorvastatin has the brand name lipitor (atorvastatin).. Its function is to lower the body's production of cholesterol and to stabilize current cholesterol plaques. The general name for this class of medication is "statins". Other statins include Crestor (rosuvastatin) ...Read more
Lipitor (atorvastatin) v Zocor: Both are effective "statins" to lower cholesterol. Atorvastatin is more effective and less toxic than simvastatin, but neither is as effective as Crestor (rosuvastatin). For 95 % of people, with proper diet/exercise neither is necessary to reach a nonhdl cholesterol of 90 (subtract good = HDL fom total cholesterol = non hdl) = where coronary artery disease ceases. See www. Thepmc. Org website. ...Read more
Statins: The milligram for milligram potency of Lipitor (atorvastatin) is higher than that for simvastatin. There is some difference in the incidence of side effects but clinically these are not seen very often. Since Lipitor (atorvastatin) became generic it has become more popular. Rosuvastatin (crestor) not generic so expensive has become very popular tho' why given its cost/pill relative to the others is debatable. ...Read more
Very similar: Atorvastatin (lipitor) is a little more potent, milligram for milligram than Simvastatin (zocor). Both have good outcome data. Both are safe. But either can cause muscle aches (in up to 10% of people) which is dependent on the dose. If muscle aches occur, a lower dose should be tried. ...Read more
Am changing from simvastatin 40mg to atorvastatin. Shall I start with atorvastatin 40mg or with 20mg? Is atorvastatin best taken at night or morning?
Dr switched me back to 40mg simvastatin after taking 20mg lipitor (atorvastatin). Should I get off the Lipitor (atorvastatin) for a few days before starting simvastatin?
Not necessary: Simvastatin 40mg is similar in potency to 20mg of lipitor (atorvastatin). There is no need to stop Lipitor (atorvastatin) for a few days before starting Simvastatin as they are similar drugs (both are statins). The Simvastatin can be started the day after stopping the Lipitor (atorvastatin) -- for most efficacy, take a statin at bedtime. ...Read more
I have a weak liver. 20mg Atorvastatin daily lowered my liver func. Hence Simvastatin 10mg every alt. Day is prescribed. Is it safe for the liver?
...: You will have to continue to monitor this with routine LFTs. elevation in LFts secondary to statin therapy is usually evident in the first 3 months of therapy and is dose dependent. It is recommended to decrease dose or change med if ALT is 3 times the upper limit of normal. If that's the case, pravachol (pravastatin) may ve an option since it is primarily metabolized by the kidneys. ...Read more
My doctor prefers pravastatin 80mg over Lipitor (atorvastatin) 20mg or simvastatin 40mg. Says it is safer but can't really tell me why. Anyone agree and if so, why?
Drug interactions: Pravastatin is metabolized differently than Lipitor (atorvastatin) or simvastatin. It may reduce the risk of adverse effects caused by interactions with other medications metabolized in the liver. (lovastatin, simvastatin, or Atorvastatin are oxidized by cytochrome p450 3a4 [cyp3a4], which is inhibited by many drugs. Pravastatin or fluvastatin are not oxidized by cyp3a4). ...Read more
For cad, which low dose of statin you use if you have perfect cholesterol numbers tc 93 tg 96& LDL 42. Pravachool, lipitor, (atorvastatin) or simvastatin. What dose?
Which statins offer cardiac help when there is CAD with normal cholesterol that you recommend to ur patients: pravastatin, simvastatin or atorvastatin?
Diet, wt. Loss 1st,,: You've got a normal cholesterol and a condition of being overweight. Depending on the extent of your cad, it would be smart to talk to your doctor about a reasonable exercise program first. This and diet would help control the CAD without statins which have many side effects and seem to just lower cholesterol. If diet and exercise fail, then drug therapy should be carefully considered. ...Read more
Side effects: The commonest side effects are muscle pain and damage. Rarely rhabdomyolysis, lysis if muscle cells may occur and is a serious issue. Other side effects include liver damage. Gastro-intestinal disorders like constipation, diarrhea, skin rashes, precipitation of diabetes mellitus and neurologic problems like memory loss. ...Read more
Rare, but not zero: Most people have no side effects from "statin" medications. A small percentage of people may get muscle symptoms and a very small number can develop life-threatening muscle cell destruction called rhabdomyolysis. Also uncommon are serious liver problems. The benefits of lowering cholesterol far outweigh the risks. Unfortunately, a misguided public scare has exagerated these risks. ...Read more
Usually none: Usually none. Some people report muscle aches or weakness, and some report memory impairment. The majority of these reports turn out not to be from the medication. There are a very small number of potentially life-threatening reactions when muscle cells break down threatening kidney damage. The benefits of cholesterol lowering greatly outweigh the risks for most people. ...Read more
Atorvastatin: Its a very safe & effective drug used for lowering cholesterol. Side effects can be muscle aches & it can respond to cq 10 (coenzyme q).Rarely one can get severe muscle pains which requires stooping the drug. You need blood tests to monitor liver enzymes which can sometimes go up, but its reversible after stooping the drug. ...Read more
Topicil, an antibiotic, not in my field of expertise
zocor: a statin, can cause muscle aches in some people;also transient liver function abnormalities
all recersible upon discontinuation of the drug
clonidine:blood pressure medication, can cause
drowsiness, slow heart beat, in high doses, even
heart block.A very good drug if used right. ...Read more
All Relatively Rare: Cholesterol (↓$, but misleading): a fat molecule manufactured by every animal cell, building block of each cell membrane (enables membrane fluidity/movement without tearing), fundamental to survival of every animal cell. Lipoproteins (proteins which transport all fats in the water outside cells) is the correct issue for artery disease (e.g. Ldl ≤700 nmol/l, HDL ≥45 µmol/l). Study: nusi. Org, lustig. ...Read more
Side effects and Yes:
The commonest side effects are muscle pain and damage. Rarely rhabdomyolysis, lysis if muscle cells may occur and is a serious issue. Other side effects include liver damage. Gastro-intestinal disorders like constipation, diarrhea, skin rashes, precipitation of diabetes mellitus and neurologic problems like memory loss.
Yes, it does help in lowering cholesterol. ...Read more
I would like to gradually reduce my 10 mg of atorvastatin as I am borderline on my cholesterol and am using zija products (moringa). Side effects?
It's your life: I'll leave others to tell you whether statins are wise if your cholesterol is borderline, or whether you can safely stop. Moringa is a poverty crop in draught-stricken parts of the world and if it has health-promoting effects, it's not clear. The work on this plant is very weak so far, though interesting. There are only three articles, all animal work in obscure journals. ...Read more
I have been prescribed simvastatin in place of crestor (rosuvastatin). Is this an acceptable alternative? I have had less side effects as a result :)
Yes: Yes it is, although it is less potent. ...Read more
Statins: This class of compounds is used to lower elevated levels of fats in the body. Common side effects include abdominal pain, diarrhea, indigestion, and a general feeling of weakness. Rare side effects include joint pain, memory loss, and muscle cramps. Cholestatic hepatitis, hepatic cirrhosis, rhabdomyolysis and myositis have been reported in patients receiving the drug chronically. ...Read more
Lipitor (atorvastatin): Lipitor (atorvastatin) is a cholesterol-lowering drug that is usually well-tolerated. However, in some patients, adverse effects such muscle injury or liver dysfunction can occur. One may present with muscle pain/weakenss if muscle cell damage occurs. With liver dysfunction, one may not have any symptoms or have vague, non-specific symptoms such as fatigue, loss of appetite. etc. ...Read more
Muscle and liver: The most important side effects involve problems with liver or muscle. Muscle pain, weakness and inflammation may occur. Liver dysfunction could also be caused by lipitor (atorvastatin). The drug could also interact with other medications so discuss all these with your doctor or pharmacist. ...Read more