Doctor insights on: Atorvastatin vs simvastatin

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Dr. Nathan Ritter
311 Doctors shared insights

Atorvastatin (Definition)

Atorvastatin has the brand name lipitor (atorvastatin).. Its function is to lower the body's production of cholesterol and to stabilize current cholesterol plaques. The general name for this class of medication is "statins". Other statins include Crestor (rosuvastatin) ...Read more


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What's the difference between atorvastatin vs simvastatin?

What's the difference between atorvastatin vs simvastatin?

Lipitor (atorvastatin) v Zocor: Both are effective "statins" to lower cholesterol. Atorvastatin is more effective and less toxic than simvastatin, but neither is as effective as Crestor (rosuvastatin). For 95 % of people, with proper diet/exercise neither is necessary to reach a nonhdl cholesterol of 90 (subtract good = HDL fom total cholesterol = non hdl) = where coronary artery disease ceases. See www. Thepmc. Org website. ...Read more

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How does simvastatin compare to lipitor (atorvastatin)?

How does simvastatin compare to lipitor (atorvastatin)?

Anti Lipid meds: Both medication are good for lowering the cholesterol but Lipitor (atorvastatin) is some what better since it has less side effect. It also has less incidence of rhabdomyelosis when used with certain other medication. ...Read more

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What the difference between atorvastatin 40mg and simvastatin 40mg?

What the difference between atorvastatin 40mg and simvastatin 40mg?

Difference: Is mainly that Atorvastarin tends to be more effective at lowering LDL at the same dose than simvastatin. ...Read more

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Simvastatin (generic zocor) or the generic for lipitor (atorvastatin)? What is the difference?

Simvastatin (generic zocor) or the generic for lipitor (atorvastatin)? What is the difference?

Statins: The milligram for milligram potency of Lipitor (atorvastatin) is higher than that for simvastatin. There is some difference in the incidence of side effects but clinically these are not seen very often. Since Lipitor (atorvastatin) became generic it has become more popular. Rosuvastatin (crestor) not generic so expensive has become very popular tho' why given its cost/pill relative to the others is debatable. ...Read more

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Simvastatin (generic zocor) or the generic for lipitor, (atorvastatin) what is the difference?

Simvastatin (generic zocor) or the generic for lipitor, (atorvastatin) what is the difference?

Very similar: Atorvastatin (lipitor) is a little more potent, milligram for milligram than Simvastatin (zocor). Both have good outcome data. Both are safe. But either can cause muscle aches (in up to 10% of people) which is dependent on the dose. If muscle aches occur, a lower dose should be tried. ...Read more

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Am changing from simvastatin 40mg to atorvastatin. Shall I start with atorvastatin 40mg or with 20mg? Is atorvastatin best taken at night or morning?

See below.: Best to take with your evening meal. Regarding the dose. It depends on how much you need to lower your cholesterol/ldl.
Atovastatin is more potent so you may be able to use a lower dose. Speak with your doctor. ...Read more

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Dr switched me back to 40mg simvastatin after taking 20mg lipitor (atorvastatin). Should I get off the Lipitor (atorvastatin) for a few days before starting simvastatin?

Dr switched me back to 40mg simvastatin after taking 20mg lipitor (atorvastatin). Should I get off the Lipitor (atorvastatin) for a few days before starting simvastatin?

Not necessary: Simvastatin 40mg is similar in potency to 20mg of lipitor (atorvastatin). There is no need to stop Lipitor (atorvastatin) for a few days before starting Simvastatin as they are similar drugs (both are statins). The Simvastatin can be started the day after stopping the Lipitor (atorvastatin) -- for most efficacy, take a statin at bedtime. ...Read more

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What is a better cholesterol lowering medicine? Lipitor (atorvastatin) or simvastatin?

Lipitor (atorvastatin) is stronger: Lipitor (atorvastatin) and now generic Atorvastatin is 'stronger' on a mg to mg basis compared to simvastatin, meaning it lowers the cholesterol 20-30% more than simvastatin. ...Read more

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I have a weak liver. 20mg Atorvastatin daily lowered my liver func. Hence Simvastatin 10mg every alt. Day is prescribed. Is it safe for the liver?

...: You will have to continue to monitor this with routine LFTs. elevation in LFts secondary to statin therapy is usually evident in the first 3 months of therapy and is dose dependent. It is recommended to decrease dose or change med if ALT is 3 times the upper limit of normal. If that's the case, pravachol (pravastatin) may ve an option since it is primarily metabolized by the kidneys. ...Read more

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My doctor prefers pravastatin 80mg over Lipitor (atorvastatin) 20mg or simvastatin 40mg. Says it is safer but can't really tell me why. Anyone agree and if so, why?

My doctor prefers pravastatin 80mg over Lipitor (atorvastatin) 20mg or simvastatin 40mg. Says it is safer but can't really tell me why. Anyone agree and if so, why?

Drug interactions: Pravastatin is metabolized differently than Lipitor (atorvastatin) or simvastatin. It may reduce the risk of adverse effects caused by interactions with other medications metabolized in the liver. (lovastatin, simvastatin, or Atorvastatin are oxidized by cytochrome p450 3a4 [cyp3a4], which is inhibited by many drugs. Pravastatin or fluvastatin are not oxidized by cyp3a4). ...Read more

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For cad, which low dose of statin you use if you have perfect cholesterol numbers tc 93 tg 96& LDL 42. Pravachool, lipitor, (atorvastatin) or simvastatin. What dose?

For cad, which low dose of statin you use if you have perfect cholesterol numbers tc 93 tg 96& LDL 42. Pravachool, lipitor, (atorvastatin) or simvastatin. What dose?

May not need: With those numbers, you may not need a statin. The ncep atp-3 goals are all met by you, even if you are at high risk, which would be an LDL less than 70. Keep up the good work, save your money and continue your diet, it appears to be working. Best wishes. ...Read more

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Which statins offer cardiac help when there is CAD with normal cholesterol that you recommend to ur patients: pravastatin, simvastatin or atorvastatin?

Which statins offer cardiac help when there is CAD with normal cholesterol that you recommend to ur patients: pravastatin, simvastatin or atorvastatin?

Diet, wt. Loss 1st,,: You've got a normal cholesterol and a condition of being overweight. Depending on the extent of your cad, it would be smart to talk to your doctor about a reasonable exercise program first. This and diet would help control the CAD without statins which have many side effects and seem to just lower cholesterol. If diet and exercise fail, then drug therapy should be carefully considered. ...Read more

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When taken simvastatin induce sever headache and dr change to atrovastatin so now ok but my friend taken simvastatin and good with this. (why?)

When taken simvastatin induce sever headache and dr change to atrovastatin so now ok but my friend taken simvastatin and good with this. (why?)

Adverse reactions: Different people's bodies respond differently to medication. While rare, headache was a reported adverse effect of simvastatin. In most cases of minor (not in intensity, but in likelihood of true allergic response or systemic damage) adverse effects, changing to a different member in the class like your doctor did often solves the issue. ...Read more

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Which statin is best for raising HDL and lowering triglycerides? [currently on 20mg Lipitor (atorvastatin) daily, was on simvistatin with previous doctor.]

Which statin is best for raising HDL and lowering triglycerides? [currently on 20mg Lipitor (atorvastatin) daily, was on simvistatin with previous doctor.]

Complicatatd: The aim-high study failed to show improved outcome with Niacin and results with tricor have been with modest and disappointing. If you have diabetes, good control will raise hdl. Exercise, eating fish, and fish oils raise hdl. O/w, the best outcomes have been assoc with crestor, lipitor, (atorvastatin) and Simvastatin regardless of HDL level. ...Read more

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Advice medication for both hyperlipidemia&hypertension from combination losartan 50mg+amlodipine 5mg with atorvastatin or rosuvastatin or simvastatin?

Depends: They are all effective. It really depends on how much lipid lowering you need. Rosuvastatin is the most potent. Discuss with your doctor. ...Read more

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How effective is simvastatin?

Very: If you are asking about how well it works for lowering cholesterol, then it is very effective ...Read more

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What is the color of atorvastatin?

What is the color of atorvastatin?

Depends on maker: Different manufacturers may use different colors. While often white, some formulations may be yellow, beige or even blue. The Amlodipine-Atorvastatin combination also comes in blue. Some generic forms come in pink. Be sure to check with your doctor and/or pharmacist that you are taking the proper pill. ...Read more

Dr. Blase Carabello
408 Doctors shared insights

Simvastatin (Definition)

Treats high cholesterol and triglyceride levels in the blood. Lowers risk of heart attack, stroke, and certain blood vessel problems in people with certain risk factors. This medicine is an hmg-coa reductase inhibitor, ...Read more


Lipitor (Definition)

Atorvastatin is a HMG-CoA enzyme blocker which is a kind of cholesterol/lipid ...Read more