Doctor insights on:
Ativan Mechanism Of Action
Acetazolamide: This drug works in the kidneys by inhibiting an enzyme called carbonic anhydrase. Carbonic anhydrase is the enzyme responsible for moving bicarbonate (sodium bicarbonate) (a base) from the kidney back into the blood stream. Acetazolamide blocks this action, resulting in more acidic blood/more basic urine. This drug has a half-life of 15 hours, so depending on the dose may take a few days to clear. ...Read more
Not known: The best info i could find on this is on the wikipedia.Com website and reads as follows : the exact mechanism by which Levetiracetam acts to treat epilepsy is unknown. However, the drug binds to a synaptic vesicle glycoprotein, sv2a,  and inhibits presynaptic calcium channels. this is believed to impede impulse conduction across synapses.. ...Read moreSee 1 more doctor answer
Comments: Over 20 plus anticonvulsant medications with a host of varying mechanisms, some affecting Na/K channels, others affecting glutamate or GABA, one even having effect on zinc metabolism. Regardless of mechanism, all are effective, and usual choice based upon tolerance of a variety of adverse events. ...Read more
CNS depressant: I don't know that anyone has an absolute lock-down on this mechanism, but you can look up what's known in goodman and gilman's pharmacologic basis of therapeutics. Gaba-a receptors are inhibitory in the brain, and their function can be enhanced by alcohol as well as sedative-hypnotic agents including benzodiazepines. Several types of ion channels in the brain are sensitive to ethanol also. ...Read moreSee 1 more doctor answer
Sibutramine/Meridia: Abbot labs voluntarily pulled sibutramine from the us market in 2010 because clinical trials showed increased risk of heart attack and stroke. Many other countries followed suit. It inhibits central reuptake of dopamine, norepinephrine, and serotonin -- serotonin mechanism may increase satiety; ne one may increase metabolic rate. Some generic forms may be available, but not by prescription. ...Read more
Acetazolamide: The half-life of acetazolamide is 10-15 hours. So that means that by roughly 15 hours, half of it has cleared, and half is still in the body. The concentration cotinues to be cut in half every 15 hours. Depending on the dosage and frequency, it lasts in the body for at least a few days. ...Read moreSee 1 more doctor answer
Acetazolamide: The half-life of acetazolamide is 10-15 hours. So that means that by roughly 15 hours, half of it has cleared, and half is still in the body. The concentration cotinues to be cut in half every 15 hours. Depending on the dosage and frequency, it lasts in the body for at least a few days. ...Read more
What chemical properties and mechanisms of action make Prozac (fluoxetine) more "stimulating" than other anti-depressant drugs in the same class?
Serotonin 2C: The agonist activity of fluoxetine at 5ht2c receptors likely explains some of the positive and negative stimulating aspects of treatment with fluoxetine in terms of appetite, activation and anxiety etc. However everyone is different and "your results may vary ". Fluoxetine is not "stimulating" for everyone. ...Read more
What is the pharmacological mechanism of action of lithium carbonate when used to treat bipolar disorder?
Unknown: The exact mechanism is not fully understood. It effects sodium transport in nerve cells and may have effects on several neurotransmitters, most notably glutamate and serotonin. It is the most effective agent for mood stability, but may have effects on thyroid and kidneys after many years of continuous use. ...Read moreSee 1 more doctor answer
Variety of Effects: I am not sure if you are asking about taking them together, or just their effects in general. On the positive side, these older antipsychotic medications can help to decrease hallucinations and bizarre thoughts. They can also decrease agitation. On the negative side, there are a variety of possible side effects, most common of which are sedation and various problems related to abnormal movements. ...Read more
How does klonopin (clonazepam) differ from Ativan in its intended effects, length of action, dosing frequency?
Depends on form: Ritalin (methylphenidate) in tablet form usually takes 30 to 45 minutes to begin working. It will peak in approximately 2 hours and the effect will last approximately 4 hours. Longer duration forms of methylphenidate (Ritalin LA) effect lasts approximately 8 hours and Concerta effect lasts from 10 to 12 hours. ...Read moreSee 2 more doctor answers
Probably: Tramadol is used for pain relief and has less addiction risks than narcotics. Pain can cause anxiety and vise versa. I believe that ativan, (lorazepam) a benzodiazepine that decreases anxiety, can increase effects of tramadol. Reisk of abuse increase though! ...Read moreSee 1 more doctor answer
Starting Adderall (dextroamphetamine and racemic amphetamine) (adhd) but on Risperdal (agitation). Won't the D2 antagonistic effect of Risperdal mitigate the action of the amphetamine?
Med interactions: Risperdal and Adderall (dextroamphetamine and racemic amphetamine) may be taken together with no significant interactions. That said, if you are taking Adderall (dextroamphetamine and racemic amphetamine) and think it is less effective, discuss with prescribing doctor who knows you best. I hope this helps. Best wishes. ...Read more
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