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Doctor insights on: Associated Positive Antinuclear Antibodies Test

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What causes false positive HCV antibody test results?

What causes false positive HCV antibody test results?

Misinformed?: Who told you that your hep c test was false? If you have no viral load that means you cleared an infection. Are you sure you are getting the right advice? ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


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Ana screen, ifa positive a (negative) means?

Ana screen, ifa positive a  (negative)   means?

Nothing by itself: One person in four tests positive. The vast majority of these people have no problems. The clinical picture is key, and how high the titer is may be helpful. ...Read more

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ANA positive SSA SSB weekly positive SCL weekly positive RNP SM weekly positive. Any implications? What are the differential diagnosis? WaDoes it mean

ANA positive SSA SSB weekly positive SCL weekly positive RNP SM weekly positive. Any implications? What are the differential diagnosis? WaDoes it mean

Pos auto ab tests: You are describing positive tests for auto antibodies. The differential diagnosis can be extensive. I am assuming a rheumatologist has ordered these tests? You need f/u with them to educate you what they mean, what further tests may need to be done and review your symptoms. Proper rheum DX is not based only on test results, but exam findings and symptoms of patient. Good luck. ...Read more

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Av test positive .Ra factor positive .Joint pain .Ccp antibody test negative.Raised esr.Plz diagnose my disease.

Av test positive .Ra factor positive .Joint pain .Ccp antibody test negative.Raised esr.Plz diagnose my disease.

Cannot diagnose: Although these lab values are interesting, taken out of the context of your symptoms and findings on physical examination, plus further testing there is no way in which to diagnose over the internet. See a rheumatologist and get appropriately assessed. ...Read more

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Cardiolipin antibodies IgM and urine protein 72mg/l ? Ana negative.

Cardiolipin antibodies IgM and urine protein 72mg/l ? Ana negative.

See details: The urine protein is within normal limits. How strongly positive is the igm cardiolipin. Only high levels of positivity have any clinical significance. Why were the tests ordered in the first place? ...Read more

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Positive HIV screener test at blood donation... Negative IFA and Negative NAT... False positive?

Positive HIV screener test at blood donation... Negative IFA and Negative NAT... False positive?

Yes: The initial screening test for HIV is very sensitive, but not very specific. The back up screening tests are much more specific for HIV. ...Read more

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What does a high positive ANA ifa test and negative choice antibody test mean?

See details: I have never heard of a choice antibody test. I positive ANA must be evaluated in the context of the clinical picture. It is a screening test for lupus but can be positive in numerous other diseases and often in people without any disease. ...Read more

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My serum test is negative for endomysial antibody iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin antibody iga?

My serum test is negative for endomysial antibody  iga, ttg tissue transglutasminase iga, gliadin antibody igg. But positive for gliadin  antibody iga?

Treat the person: Lab tests mean nothing in isolation, and have many false positives and false negatives. The decision to make a trial of a gluten-free diet will be between you and your gastroenterologist or dermatologist based on the big picture. ...Read more

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Hiv ab,1/2, eia with relx result repeatedly reactive. HIV 1/2ab differentiation w/refl hiv1 antibody negative hiv2 antibody negative. pos or neg hiv?

Hiv ab,1/2, eia with relx result repeatedly reactive. HIV 1/2ab differentiation w/refl hiv1 antibody negative hiv2 antibody negative. pos or neg hiv?

It depends: In a situation like this you have one positive test and one negative test. The lab should run a tie-breaker test (HIV RNA) to give you a real answer. Also, the first test may be an older test 2nd or 3rd generation) instead of the latest 4th generation) test. It also depends on if you have flu-Like symptoms. Seek help from a specialist in HIV who can help you understand. ...Read more

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Positive ana positive rnp low positive ccp positive dsdna can you tell me if this means lupus or mctd?

?: depends on the clinical picture as well, results point towards auto immune disorder, but need to be put in clinical context and follow up to commit to a diagnosis ...Read more

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Hepb surface antigen positive, confirmatory test negative, antibody and core negative, should I worry?

Hepb surface antigen positive, confirmatory test negative, antibody and core negative, should I worry?

Possibly: Do not understand how initial test was positive and "confirmatory" test negative. Need to repeat these, although you may be in the "window" period, when antigen is being consumed by forming antibody and neither is measurable. Wait 3 months and retest antibody titers. By then you may be hepb antibody and core antibody positive, in which case you are immune. ...Read more

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I'm having negative DNA ,Sm and Rnp antibodies, but positive sm/rnp antibody,and high ANA titre speckled,so what is the diagnosis ?

Lupus: These serologies are rather non specific. The speckled ANA is non specific. In Systemic Lupus Erythematosis (SLE) it is usually homogeneous in its staining. Anti-Sm and Anti RNP can be see in mixed connective-tissue diseases and overlaps with SLE, scleroderma and myositis. As often is the case a specific diagnosis cannot be made. You need to see a Rheumatologist. ...Read more

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What would cause a high positive ANA (1:640) speckled, nucleolar with a low positive smooth muscle antibody (1:40) but negative SS-A, SS-B, anti-Smith, RNP, SCL-70, Anti Jo antibodies? Liver disease?

What would cause a high positive ANA (1:640) speckled, nucleolar with a low positive smooth muscle antibody (1:40) but negative SS-A, SS-B, anti-Smith, RNP, SCL-70, Anti Jo antibodies? Liver disease?

Probably normal: Many people have a positive ANA without being sick. If you also have elevated liver enzymes, a workup for autoimmune hepatitis may be continued, but if there's nothing to suggest a liver problem biochemically, I'd not be in a hurry to diagnose despite anti-smooth-muscle. ANA means nothing apart from the clinical picture. Best wishes. ...Read more

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Is a core positive antibody for hepetitis b is dangerous. Igm antibody negetive. Surface antigen negetive with surface antibody positive. Explain?

Is a core positive antibody for hepetitis b is dangerous. Igm antibody negetive. Surface antigen negetive with surface antibody positive. Explain?

Past infection: The results you described are consistent with a past infection with hepatitis b from which you have recovered. You body made antibodies to the constituents of the virus. These results are not a cause for concern. ...Read more

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Can an HIV antibody screening test be positive but the western blot negative?

Can an HIV antibody screening test be positive but the western blot negative?

Yes: There are 2 reasons for this kind of result: (1) a false positive, or (2) early infection before seroconversion. In someone at low risk for HIV without symptoms, another negative WB in 1 month means there's no infection. In someone at risk or with symptoms of acute infection, a viral load can be helpful. The new 4th generation antigen/antibody tests will eliminate this problem. ...Read more

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What does a weakly positive ANA with only rnp antibodies indicate?

Specific to patient: The test by itself is not diagnostic.. It depends on your evaluation, examination, clinical factors are the most pertinent. The lab reports are guidelines but not diagnostic in themselves. ...Read more

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Can you please explain ENA. Negative anti-CCP antibody 5 (<5) positive RF <14(0-14) antinuclear 80 (<80) a low titre is present?

See details: None of those results is impressive and all are negative except for a borderline ANA. Why were the tests ordered in the first place? These tests must be evaluated in the context of the clinical symptoms. ...Read more

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What does antinuclear antibody detected on cardiolipin ab (igg) results imply?

Different tests: ANA can be found with connective tissue diseases and also in normal people. Cardiolipin antibodies suggest circulating anticoagulant, which can be found in people with lupus, but also with many other diseases. ...Read more

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Positive ANA 1:160 homogeneous, positive EBV (via, igg) at 3.97 H. See rheumatologist? Possible diagnoses?

Symptoms?: We treat patients not lab results, you can still see a rheumatologist to sort things out for you, best wishes ...Read more

Dr. Alfred Kim
25 doctors shared insights

Antinuclear Antibodies (Definition)

Antinuclear antibodies present - about half of those who have this have an auto-immune disease. ...Read more