Top
10
Doctor insights on: Aspergers Gaba Receptor Genes

Share
1

1
A lack of GABA and dopamine in asperger's syndrome? What role does serotonin play in asperger's?

A lack of GABA and dopamine in asperger's syndrome? What role does serotonin play in asperger's?

Aspergers: Research is suggesting spectrum kids may be awash in serotonin in utero. There is speculation that ssri's may not be the best route in treating some of the difficulties associated with the spectrum because there may already be too much serotonin. Hopefully, future research will clarify. This is my take on the spectrum. http://www.youtube.com/watch?v=xg1ngp1ngds. ...Read more

Receptor (Definition)

An organ, cell or molecule that accepts an outside signal and causes an internal change. Eyes receive light, touch receptors send messages to the brain when stimulated by pressure and estrogen receptors bind Estradiol causing responses of normal breast, ovary and uterus cells to rising and falling levels of the female steroid hormones. Most of the time "receptor" refers to one ...Read more


2

2
Is ethanol meant to be the natural exogenous ligand for the GABA receptor?

Intriguing idea: As physicians, we are science based, and apply our knowledge to individual patients, which is the art of medicine. Your question, which is a blend of philosophy and religion, is best answered by someone in that realm. ...Read more

See 1 more doctor answer
4

4
Does alcohol bind directly to GABA receptors or does i increase GABA release?

See below: Alcohol, shown in black, also binds to the gaba receptors, and increases the quieting effect that gaba has on neurons. Researchers are not sure exactly how it does so, but one theory holds that it causes the ion channels to stay open longer, thus increasing the ion flow. The result is a much greater quieting effect on the brain. ...Read more

5

5
Does alcohol actually bind to GABA receptors or just increase GABA neurotransmition? Or a combination of both?

Does alcohol actually bind to GABA receptors or just increase GABA neurotransmition? Or a combination of both?

Complicated!: Specific gabaa receptor subtypes are sensitive at lower doses (social drinking) while other subtypes respond to ethanol at doses attained by severe intoxication. Furthermore, it increases gabaergic neurotransmission through indirect effects, including the elevation of endogenous gabaergic neuroactive steroids, presynaptic release of gaba, and dephosphorylation of gabaa receptors. ...Read more

See 1 more doctor answer
6

6
How long does it take for GABA receptors to heal after while in clonazepam withdraw?

How long does it take for GABA receptors to heal after while in clonazepam withdraw?

See below: Any particular receptor is "healed". You want to know how long it takes for gaba function and tone to normalize after using benzos. Rule of thumb- one month for every year of continuous use. ...Read more

See 1 more doctor answer
7

7
What is difference between GABA receptor and ssri receptor, so both of them is the same from point of treatment.

What is difference between GABA receptor and ssri receptor, so both of them is the same from point of treatment.

GABA and serotonin.: I hope you are ready for a very long read. I found an excellent lecture online addressing this. Go to the link noted below.Role of serotonin and gaba in anti-anxiety effects of ... www.flyfishingdevon.co.uk/salmon/year2/psy221anxiety/psy... This lecture discusses the role of serotonin and gaba best wishes and have fun reading. ...Read more

8

8
Is there a specific binding site just for alcohol on the GABA receptor just like there's a specific benzodiazepine binding site?

Is there a specific binding site just for alcohol on the GABA receptor just like there's a specific benzodiazepine binding site?

Complicated!: Specific gabaa receptor subtypes are sensitive at lower doses (social drinking) while other subtypes respond to ethanol at doses attained by severe intoxication. Furthermore, it increases gabaergic neurotransmission through indirect effects, including the elevation of endogenous gabaergic neuroactive steroids, presynaptic release of gaba, and dephosphorylation of gabaa receptors. ...Read more

See 2 more doctor answers
9

9
Is there any chance that GABA receptors afected by fluoroquinolones toxicity recover themselfes in time ?And if yes in how much time aprox?

Yes: Yes, the receptors are constantly recycled in the cell membranes. Amount of time varies from cell type to cell type and also by receptor type. Should be largely recovered in a week, i would think. ...Read more

10

10
How much time for GABA antagonist to unbind from GABA receptor site?Levaquin (levofloxacin) has binded to my GABA receptors.1month off levaquin&feel the same.

How much time for GABA antagonist to unbind from GABA receptor site?Levaquin (levofloxacin) has binded to my GABA receptors.1month off levaquin&feel the same.

Not long: Levofloxacin is hypothesized to cause neuropsych symptoms via a combination of its gaba antagonism and nmda agonism. With that said, it is highly doubtful that symptoms you're experiencing one month following ingestion are caused by levofloxacin, whose half-life is 6-8 hours and therefore is no longer in your system. I would be looking for other causes. ...Read more

Gene (Definition)

A hereditary unit consisting of a sequence of dna that occupies a specific location on a chromosome and determines a particular characteristic in an organism. Genes undergo mutation when their ...Read more


Gaba (Definition)

Gamma-aminobutyric acid (also known as gaba)is used as a supplement ...Read more