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Doctor insights on: Asacol

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Dr. Katharine Cox
45 doctors shared insights

Asacol (Overview)

Asacol is a gastroenterology drug.


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What is the difference between asacol (mesalamine) and lialda. Do some people have different side effects to one vs the other/?

What is the difference between asacol (mesalamine) and lialda. Do some people have different side effects to one vs the other/?

See below: Both meselamine (5-amino-salicylic acid).Lialda is long-acting and is taken 2Xdaily.Asacol (mesalamine) is not long acting and is taken 3 Xs daily.Asacol (mesalamine) is no longer available in the U.S.but can be obtained in the rest of the world and it is MUCH cheaper than Lialda.You can fax your prescription to a Canadian pharmacy for asacol(different trade name but same thing) if u have to pay Lialda out of pocket.Best ...Read more

Dr. Katharine Cox
45 doctors shared insights

Asacol (Overview)

Asacol is a gastroenterology drug.


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Will pepto interfere with asacol (mesalamine)?

Unlikely: Pepto and Asacol (mesalamine) , if taken together, should not cause any issues . You shouldn't need both together though ...Read more

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Im passing asacol (mesalamine) out whole. Does colazal release differently than asacol (mesalamine) or is it also pH dependent? And does it work the same?

Im passing asacol (mesalamine) out whole. Does colazal release differently than asacol (mesalamine) or is it also pH dependent? And does it work the same?

Different release: While Asacol (mesalamine) release is ph dependent, Colazal does not become active until the drug reaches the colon where bacteria there splits the drug up into an active state. In fact, the capsule is just a formality as the Colazal powder can be swallowed whole - as it is available overseas. Having said that, many of my patients also see intact Asacol (mesalamine) tabs in their stools. ...Read more

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Is it safe for me to have botox facial injections whilst on infliximab, methotrexate and asacol (mesalamine) treatment for ulcerative colitis?

It is safe: Botox does not interact with these and almost all other medications. I have several patients with colitis on these drugs and have injected Botox for their chronic migraines without any side effects. ...Read more

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Can I take ibuprofen while on asacol (mesalamine) hd? I am not allergic to either one.

Can I take ibuprofen while on asacol (mesalamine) hd? I am not allergic to either one.

Yes: No significant interactions have been reported between Asacol hd & ibuprofen. Avoid using another salicylate (aspirin, peptobismol) in place of Ibuprofen (could lead to salicylate toxicity). Do not take antacids, acid blockers like Zantac (ranitidine) family or Prilosec family at same time as Asacol as they may decrease its effectiveness. ...Read more

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Using colocort enema every 3 days to control inflammation from colitis in addition to asacol (mesalamine) daily. Is long time usage of colocort bad? No problem yet

Using colocort enema every 3 days to control inflammation from colitis in addition to asacol (mesalamine) daily. Is long time usage of colocort bad? No problem yet

Maybe: Colocort is a steroid medication. Although you are using it in limited fashion and in a topical form, there is still systemic absorption and, over time, steroid side effects can occur (bone loss, glucose intolerance, hip problems, cataracts, etc). Best to discuss your concerns with your provider to see if Mesalamine enemas would help or if you need a different steroid sparing medication. ...Read more

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So now I am taking Prilosec and asacol (mesalamine) hd. Is what are the possible side effects?

See below: Taking Asacol (mesalamine) hd & Prilosec at the same time may reduce the effectiveness of the asacol (mesalamine). Allow at least 2-3 hours between them. If the Asacol (mesalamine) irritates your stomach, take the Prilosec first, followed by the Asacol (mesalamine) a few hours later. Other antacids, acid blockers like zantac/pepcid will interact with Asacol (mesalamine) in the same way as prilosec; so space the meds apart when you take them. ...Read more

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What is the treatment for asacol (mesalamine) overdose?

What is the treatment for asacol (mesalamine) overdose?

Nothing: Should be no need to treat however there is a theoretical chance of kidney damage that would need to be supportively managed. ...Read more

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My stool has been looking like small pebbles of white pellets. Am a new uc patient (dx in july) on asacol (mesalamine). Some brbpr, but not as much as before.?

My stool has been looking like small pebbles of white pellets.  Am a new uc patient (dx in july) on asacol (mesalamine).  Some brbpr, but not as much as before.?

Pellets in stool?: Could be Asacol (mesalamine) pellets after breakdown of capsule in lower bowel (colon). Sounds like improvement re: bleeding (inflammation). Should have follow up with md, since it has been 6 months on meds; may need to adjust them. ...Read more

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What is the difference between asacol (mesalamine) ec and asacol (mesalamine) hd dr?

Asacol (mesalamine): Regular Asacol (mesalamine) is 400 mgs in strtength.Asacol (mesalamine) hd is double strength it has 800 mgs. ...Read more

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Will pepto interfere with asacol (mesalamine)?

Unlikely: Pepto and Asacol (mesalamine) , if taken together, should not cause any issues . You shouldn't need both together though ...Read more

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Does asacol (mesalamine) become toxic past its expiration date?

Uncertain: In general, it is recommended that medications not be used after expiration date. With that said, there is a big difference between being expired for 5 days versus 5 years. Your pharmacist should be able to provide more information. ...Read more

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What is the treatment for asacol (mesalamine) overdose?

Nothing: Should be no need to treat however there is a theoretical chance of kidney damage that would need to be supportively managed. ...Read more

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Endocort for diarrhea instead of asacol (mesalamine) is it better?

Depends!: Entacort-la 3mg is a mostly non-absorbed steroid given for bowel inflammation. If you have diarrhea from a non-inflammatory cause, you should not take it. But Asacol (mesalamine) is also for inflammation of the bowel. If you do, it is what works best for you! ...Read more

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What is the difference between asacol (mesalamine) and lialda. Do some people have different side effects to one vs the other/?

See below: Both meselamine (5-amino-salicylic acid).Lialda is long-acting and is taken 2Xdaily.Asacol (mesalamine) is not long acting and is taken 3 Xs daily.Asacol (mesalamine) is no longer available in the U.S.but can be obtained in the rest of the world and it is MUCH cheaper than Lialda.You can fax your prescription to a Canadian pharmacy for asacol(different trade name but same thing) if u have to pay Lialda out of pocket.Best ...Read more

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Im passing asacol (mesalamine) out whole. Does colazal release differently than asacol (mesalamine) or is it also pH dependent? And does it work the same?

Different release: While Asacol (mesalamine) release is ph dependent, Colazal does not become active until the drug reaches the colon where bacteria there splits the drug up into an active state. In fact, the capsule is just a formality as the Colazal powder can be swallowed whole - as it is available overseas. Having said that, many of my patients also see intact Asacol (mesalamine) tabs in their stools. ...Read more

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Doctors, do you think I can die from an asacol (mesalamine) and darvocet overdose?

Doctors, do you think I can die from an asacol (mesalamine) and darvocet overdose?

Asacol (mesalamine) darvocet: Asacol (mesalamine) unlikely as it is mainly anti-inflammatory - but with an overdose you may have some severe side effects. DArvocet certainly yes. The metabolite is cardiotoxic and with an overdose you can potentially die. ...Read more

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Dr. Robert Richards
60 doctors shared insights

Mesalamine 5 Asa (Definition)

Mesalamine 5-ASA ...Read more