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Doctor insights on: Arthritis Drug Ana Kineret Reached

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Is it bad to use the arthritis drug ANA kinra kineret (anakinra)?

Is it bad to use the arthritis drug ANA kinra kineret (anakinra)?

Speak w/ your Doctor: Only you and your physician can make the final decision as to which medicatinos may or may not be right for your situation. All medications have known side effects. As long as the good effects significantly outweigh the bad effects, then you may condsider Kineret (anakinra) as a reasonable option for treating your rheumatoid arthritis. ...Read more

Dr. Thomas Namey
2,423 doctors shared insights

Arthritis (Definition)

A condition where there is progressive degeneration of one or more joints. Symptoms may include joint pain, swelling, decreased motion, and stiffness. The two most common types of arthritis are osteoarthritis, which is associated first with articular cartilage breakdown with a component of inflammation, and rheumatoid arthritis, which is a systemic autoimmune disorder that affects joint linings first and secondarily ...Read more


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Has any one taken the disease modifying drug (dmards) for their psoriatic arthritis?

Has any one taken the disease modifying drug (dmards) for their psoriatic arthritis?

Most patients need a: Psoriatic arthritis can be a very inflammatory disease. We all want pain relief for our patients, but rheumatologists understand the need to reduce inflammation, because it portends coniued damge to joints, as well as much earlier cardiac disease. My personal favorites: sulfasalazine with methotrexate, the latter given sc. Some, albeit few, patients need tnf-alpha inhibitors. ...Read more

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38y female seroneg ra. Plaquenil (hydroxychloroquine) not work. Bone scan show si joints & feet. Start 10mg mtx. Doc said may not be RA since si joints?4 relative w/ra. ?

38y female seroneg ra. Plaquenil (hydroxychloroquine) not work. Bone scan show si joints & feet. Start 10mg mtx. Doc said may not be RA since si joints?4 relative w/ra.  ?

Talk to your doctor: There are other forms of inflammatory arthritis, which include the seronegative spondyloarthropathies. It might be something like ankylosing spondylitis. Additional testing might be necessary, and a rheumatology referral may be necessary. Also keep in mind being seronegative does not mean you absolutely don't have rheumatoid arthritis. ...Read more

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Is arava (leflunomide) effective for rheumatoid arthritis?

Is arava (leflunomide) effective for rheumatoid arthritis?

It may be...: Again, this is a question for the treating specialist, most likely a rheumatologist. When treating a disorder like ra, there are a variety of medications that have been effective; as with everything else in medicine, no one size fits all, and the right drug or combo for each must be assessed over time by a specialist. ...Read more

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I tested positive for the ANA screen, 1:160 titer, speckled pattern. Rheumatoid factor 21, SED rate 22. Does this indicate Rheumatoid arthritis?

I tested positive for the ANA screen, 1:160 titer, speckled pattern. Rheumatoid factor 21, SED rate 22. Does this indicate Rheumatoid arthritis?

No: The rheumatoid factor was barely above negative. It is usually greater than 150 in RA. The CCP antibody is a much more specific test. The diagnosis of RA depends on several diagnostic criteria. The rheumatoid factor is nonspecific. ...Read more

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Does Simponi (golimumab) Aria for rheumatoid arthritis have any effect when taken without methotrexate?

Does Simponi (golimumab) Aria for rheumatoid arthritis have any effect when taken without methotrexate?

Simponi (golimumab) and RA: Dear Jennifer, Simponi also known as golimumab, in combination with methotrexate has been shown to improve severe RA; Clinical symptoms of joint pain and swelling as well as less radiographic damage were noted. Therefore the short answer to your question is Yes! Best wishes, Nisha ...Read more

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Is there anybody taking anti-tfn infliximab for rheumatoid arthritis?

Many patients!: Results are very good, particulary when used alone and better with methotrexate. The dirrence with Remicade (infliximab) is that it blocks the tnf-a receptor, rather than binding tnf-a itself, but it accomplishes the same thing. It's infusion intervals are longer, because the turnover of recptors is slower than the production of tnf-a itself. A good choice for those who do not want to inject themselves sc. ...Read more

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For juvenile arthritis is methotrexate safe?

For  juvenile arthritis is  methotrexate  safe?

Very safe!: Although i frequently use other agents for jia, i frequently add mtx to the therapeutic mix. Considering that the dose should be lower, i still favor the subcutaneous route rather than oral. However, I have not had serious issues with mtx and children. Make sure they get supplemental folic acid! ...Read more

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Is methotrexate or humira (adalimumab) better for rheumatoid arthritis?

It's u as much as Rx: Again, this is a question for the treating specialist, most likely a rheumatologist. When treating a disorder like ra, there are a variety of medications that have been effective; as with everything else in medicine, no one size fits all, and the right drug or combo for each must be assessed over time by a specialist. ...Read more

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Mild Psoriasis sufferer, chronic pain right forarm & elbow. Blood tests 80 titre ana, positive anticentromere. Psoriatic arthritis or scleroderma?

Mild Psoriasis sufferer, chronic pain right forarm & elbow. Blood tests 80 titre ana, positive anticentromere. Psoriatic arthritis or scleroderma?

Occam's Razor: Usually Systemic Sclerosis and/or limited Scleroderma is not characterized by arthritis like you describe. The typical biomarker the anti Scl-70 (anti-topoisermorase). Symptoms have to be put into context and better described than elbow and forearm pain. This one you should see a rheumatologist about. Dermatology would be useful as well. Best of luck! ...Read more

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Early Ra. AntiCCP + 17. Other blood negative. Doc1: MTX 7.5mg, Plaquenil 400mg, Celebrex (celecoxib). Doc2: Plaquenil 200mg, Pred 5mg, Celebrex (celecoxib) . Confused. ?

Early Ra. AntiCCP + 17. Other blood negative. 

Doc1: MTX 7.5mg, Plaquenil 400mg, Celebrex (celecoxib). 

Doc2: Plaquenil 200mg, Pred 5mg, Celebrex (celecoxib) . 

Confused. ?

Reasonable: You have the opportunity to do very well. Early RA responds better to any of the treatments compared to late RA (disease > 2 years). If you still have pain, stiffness, fatigue on this regimen, talk to your Rheumatologist about adding a biologic medication such as Enbrel, Humira or Remicade (infliximab). There are several others, but I usually start with one of these. Would help get rid of the prednisone. ...Read more

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RA + psoriasis. MTX allergy. Enbrel (etanercept) non effective. Humira semi-effective but Vectra score 30 with extreme fatigue. MD wants to try Xeljanz?

RA + psoriasis. MTX allergy. Enbrel (etanercept) non effective. Humira semi-effective but Vectra score 30 with extreme fatigue. MD wants to try Xeljanz?

RA + psoriasis: There are a number of newer medications that could help you. Xeljanz works by disrupting cytokine and growth factor signaling pathways. A trial of the medication is useful to see whether it helps you. Other medications that might help include Remicade (infliximab) and Apremilast ...Read more

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On arava (leflunomide) 20mg, enbrel 50mg weekly, methotrexate 25mg. Any other rheumatologist prescribed this for psoriasis/psor. Arthitis?I'm worried about my liver.

On arava (leflunomide) 20mg, enbrel 50mg weekly, methotrexate 25mg. Any other rheumatologist prescribed this for psoriasis/psor. Arthitis?I'm worried about my liver.

Follow laboratory: You are correct that liver problems are risk with this regimen. Your physician needs to be certain that you are followed closely and correctly. Your own responsibility is to refrain from alcohol, and be certain no additional medicines you take do not worsen this risk. If you are concerned you need to discuss this with your physician. There are other therapy choices available. ...Read more

Ana (Definition)

An "ana" is a blood test used to screen a person for the possibility of several autoimmune diseases. It is important to remember that this is a screening test and a positive result only indicates more testing may be warranted. No blood test is perfect, and getting to a diagnosis is usually much more complex than drawing blood and looking at a number ...Read more


Dr. Robert Lowe
1,556 doctors shared insights

Painful Joints (Definition)

That term is not really a specific diagnosis, but rather somewhat of a general term. The medical term is arthralgias, which implies pain in multiple joint possibly coming from a single cause. Don't hesitate to be seen and evaluated for ...Read more