Top
10
Doctor insights on: Aromatase Inhibitors

Share

Aromatase Inhibitors (Overview)

An aromatase inhibitor is a medicine that blocks the conversion of androgens in fat cells to the strong estrogen (estrone).


1

1
What are some benefits and risks of taking aromatase inhibitors?

What are some benefits and risks of taking aromatase inhibitors?

Benefits > downsides: Hormonal therapy has systemic benefits in er+ patients (similar to chemo), reduces local recurrence after breast conservation, and reduces the risk of second/new breast cancers. Head to head each of these is slightly better for ais than tamoxifen. Ais major side effects are menopausal symptoms, bone and joint symptoms (arthralgias), and decrease in bone density. ...Read more

See 1 more doctor answer

Aromatase Inhibitors (Overview)

An aromatase inhibitor is a medicine that blocks the conversion of androgens in fat cells to the strong estrogen (estrone).


2

2
Can aromatase inhibitors be used to increase final height in puberty in boys?

Can aromatase inhibitors be used to increase final height in puberty in boys?

May be effective: For boys with short stature, and no other known cause, aromatase inhibitors have been used. It is still considered experimental, and it is not clear that it will increase adult height. Much depends on the specific condition. As with anything that may increase testosterone, there are side effects. You should only do this under the care/supervision of a pediatric endocrinologist. ...Read more

3

3
Are 'aromatase inhibitors' healthy to take regularly?

Are 'aromatase inhibitors' healthy to take regularly?

Maybe but for what?: All medications, prescription & otc, as well as all dietary supplements, have potential side effects. There is no free lunch, no side effect free pill, whether medication or supplement. Aromatase inhibitors are approved for use in breast cancer in which case the potential risk of liver damage, hypertension, etc probably outweighs risk of recurrent breast cancer. So talk to your doc re what's right. ...Read more

4

4
What is the definition or description of: aromatase inhibitors?

What is the definition or description of: aromatase inhibitors?

Aromatase inhibitor: An aromatase inhibitor is a medicine that blocks the conversion of androgens in fat cells to the strong estrogen (estrone). ...Read more

See 1 more doctor answer
5

5
What are some benefits and risks of taking aromatase inhibitors?

Benefits > downsides: Hormonal therapy has systemic benefits in er+ patients (similar to chemo), reduces local recurrence after breast conservation, and reduces the risk of second/new breast cancers. Head to head each of these is slightly better for ais than tamoxifen. Ais major side effects are menopausal symptoms, bone and joint symptoms (arthralgias), and decrease in bone density. ...Read more

See 1 more doctor answer
6

6
Any over-the-counter aromatase inhibitors?

No: There are no over the counter aromatase inhibitors. They are only available by prescription. ...Read more

7

7
Is there a homeopathic alternative for aromatase inhibitors?

Is there a homeopathic alternative for aromatase inhibitors?

No: If you have been prescribed aromatase inhibitors, presumably you have hormone sensitive breast cancer. Do not substitute the homeopathic placebo for your medications. The data on breast cancer treatment is solid for aromatase inhibitors and using a homeopathic placebo might prove lethal. ...Read more

See 1 more doctor answer
8

8
Can aromatase inhibitors be used to increase final height in puberty in boys?

May be effective: For boys with short stature, and no other known cause, aromatase inhibitors have been used. It is still considered experimental, and it is not clear that it will increase adult height. Much depends on the specific condition. As with anything that may increase testosterone, there are side effects. You should only do this under the care/supervision of a pediatric endocrinologist. ...Read more

9

9
Does fda approved aromatase inhibitors in pediatrics?

Does fda approved aromatase inhibitors in pediatrics?

Probably never will: Many of the drugs we use in pediatric oncology are never approved by the fda for treatment of a particular pediatric cancer. Once it gains fda approval for an adult disease indication, we then can study it in clinical trials, and if warranted, use it. ...Read more

See 2 more doctor answers
10

10
Need help in reducing e2 (oestradiol). Need some advice in dosing aromatase inhibitors. Tried arimidex as well as aromasin (exemestane) but got bone mineral loss..

Need help in reducing e2 (oestradiol). Need some advice in dosing aromatase inhibitors. Tried arimidex as well as aromasin (exemestane) but got bone mineral loss..

Go see your doctor: Presumably you're taking Arimidex (anastrozole) to control your Estradiol to treat gynecomastia (rather than trying to jack up your testosterone). Loss of bone mineral density is a known consequence of excessively lowering one's estradiol. I'm not clear what kind of trouble you're having w/your dosing since you didn't mention your regimen. Regardless, you need to address your concern w/your doctor. ...Read more