Doctor insights on:
Arimidex And Osteoporosis
No: Tamoxifen is a selective estrogen receptor modulator (serm) that is used to treat/prevent breast cancer. Evista (raloxifene) is also a serm and it is used to treat/prevent osteoporosis (it also reduces the risk of invasive breast cancer in at risk women). Tamoxifen does not cause osteopenia or osteoporosis. Tamoxifen has been shown to preserve bone. ...Read moreSee 1 more doctor answer
No: First, with osteoporosis, the bone i not dead it is only decreased in amount bone is living and has the ability to heal. People with osteoporosis will heal a fracture. Boniva (ibandronate) slows the rate of bone loss but does not stimulate the growth of new bone. However, since the body continues to make bone, the density usually goes up with Boniva (ibandronate) and similar meds. Few treatments have proven to make new bone. ...Read moreSee 1 more doctor answer
70 yo female w/osteoporosis and family hx of BRCA breast cancer. Ok to Denosumab and Reloxifene therapy together??
Yes it is OK: You can take these medicines together. There is no significant interaction or harm. So relax and take them as advised by your doctor. ...Read more
Acto-no: In my experience the patented drudeveloped to improve the bine density scan have not proven to prevent bone fractires. In fact, the black box warning states that these drugs cause brittle bone and increases risk of fracture. The ultimate goal in medicine is to get clinical outcomes while doing no harm. Bio identical hormone replacement has been proven to both produce bone & and stop bone loss. ...Read more
Not much: That is statistically different from placebo, though everything under the sun has been reported it is hard to link it to the drug. The one side effect that is different by about2% is infection, do I would not give it to a compromised person or one who had an acting infection. The debate ove osteonecrosis of the jaw continues on. ...Read moreSee 2 more doctor answers
Sort Of: We define cancers by their organ of origin. Therefore, by strict definition, bone cancer originates from bone cells; Anastrozole won't help these rare cancers. More commonly, cancers can spread to bones--we call this bone metastasis. Breast cancer can spread to bones; anastrazole can prevent the spread of certain breast cancers. Hope this helps. ...Read more
What should a person with breast cancer IV take after tamoxifen and aromasin. Arimidex femara or faslodex (fulvestrant)?
Treatment options: For stage IV breast cancer- if the cancer progressed after tamoxifen and aromasin- depending on several factors such as how much cancer burder, involvement to visceral organs, overall condition etc- the options would be- faslodex; combination of Aromasin (exemestane) and evorilimus ( based on recent randomized clinical trial) or chemotherapy. Discuss further with your oncologist- which one for your case. ...Read moreSee 1 more doctor answer
One answer: Calcium and vitamin d supplements certainly are a part of reducing bone loss. Depending on your age, a DEXA or bone denstiy test may be in order to measure your bone density and see if bone loss is present. If so, other therapy may be indicated. Also weight bearing exercise is important in helping maintain bone density. ...Read more
Need help in reducing e2 (oestradiol). Need some advice in dosing aromatase inhibitors. Tried arimidex as well as aromasin (exemestane) but got bone mineral loss..
Go see your doctor: Presumably you're taking Arimidex (anastrozole) to control your Estradiol to treat gynecomastia (rather than trying to jack up your testosterone). Loss of bone mineral density is a known consequence of excessively lowering one's estradiol. I'm not clear what kind of trouble you're having w/your dosing since you didn't mention your regimen. Regardless, you need to address your concern w/your doctor. ...Read more
Possibly: Femara (letrozole) is an aromatase inhibitor. It works by decreasing the amount of estrogen produced in post-menopasual women. Anything that lowers estrogen level will take away its protective effect on bone, thus increasing the risk of fracture, osteopenia or osteoporosis. ...Read moreSee 1 more doctor answer
There is no : Permanent cure for osteoporosis, Raloxifene (evista) mimics estrogen's beneficial effects on bone density in postmenopausal women, without some of the risks associated with estrogen. Taking this drug may also reduce the risk of some types of breast cancer. Hot flashes are a common side effect. Raloxifene also may increase your risk of blood clots. ...Read more