Doctor insights on:
Aricept Namenda Memantine
My mom has dementia. She is on celexa, aricept, namenda (memantine) and risperdal. She takes low to normal doses. She has gained 70 lbs in 18 months and feels tired all the time. Is it expected? Suggestions?
MEDICATION EFFECTS: Do not recommend use of Risperdal in this situation, as there is a substantial risk of stroke or death, in those elderly folks who have dementia. Of course, I fully agree that the weight gain and fatigue is also due to this drug. Is there are major issue with stopping it in view of all the potential problems? Is her diagnosis confirmed, such as alzheimer's? Should you get a second opinion? ...Read more
Donepezil is a medication indicated for the treatment of alzheimer's disease that increases acetyl choline (a chemical involved in memory). While it does not cure the disease, it has potential for preserving the quality of life of a sufferer when compared to not treating. For instance, it has been showed to delay the time ...Read more
Tough to be sure: These medicines are designed to help slow the progression of Alzheimer's disease. Since it doesn't necessarily improve symptoms, it can be difficult to know if it is working or not. There have been some studies with Aricept (donepezil) showing that even in severely demented individuals, there is still benefit. If there is no quality of life (i.e. No communication, no adls), I would stop the medicine. ...Read more
Worsening: Back to a baseline, significantly lower level of functioning is the most common phenomenon, which is seen by family/staff as a sudden worsening of the dementia (depending on the stage), it may consist of forgetting names, inability to execute simple tasks, not recognizing people/places, incontinence, etc. ...Read more
Early vs later stage: Both relieve symptoms of the disease & focus on neurotransmitters key to memory and learning. Aricept focuses on acetycholine in an attempt to slow its loss because of alzheimer's. Namenda (memantine) focuses on glutamate, blocking the excess produced as a part of the disease. Namenda (memantine) is better suited to moderate to advanced stages of alzheimer's, while Aricept is for early onset through advanced stages. ...Read more
Yes: They both have advantages and disadvantages. To learn about the risks and benefits to make a decision you should consult your doctor. ...Read more
My father has alzheimers. Aricept and namenda (memantine) had worked well-but not so well lately. What's next?
My mom was diagnosed with ft dementia and is on Aricept and namenda (memantine). She is doing better, but do thesedrugs together slow down progression? There is conflicting information on the internet.
Do not slow disease: Aricept and Namenda (memantine) can slow functional decline in early alzheimer's. There is some evidence that Namenda (memantine) can help some of the language difficulties in ft dementia. There is some evidence that Aricept can worsen behaviors in those with ft dementia. There are no known treatments that slow or stop brain death in alzheimer's or ft dementia. Namenda (memantine) can help decrease anxiety, agitation and aggressio. ...Read more
Mom in mid-stage ft dementia. Gets bloodshot eyes every 3-4 wks. On namenda, (memantine) aricept, 0.25mg risperdal. Most likely drugs or disease the cause?
Partly,: Persons with dementis blink a lot less than needed. You see them staring off into space. The eyes are usually red form dryness irritation. Use lubricating eye drops as needed-; refresh, systane or blink eyes drops all are available as over the counter treatment. ...Read more
I stopped taking namenda (memantine) a few days ago because of confusion problems, how long do the effects last after stopping? I now take Donepezil 5mg
Good change, I hope: The half-life of Namenda (memantine) is no more than 80 hrs. This should mean that it will be unlikely to still have and effects in a week to 10 days. But your doctor or a pharmacist may explain it better. The new drug should not have that side effect, but watch it and discuss risks w/ the doctor too. Best wishes for good results! ...Read more
Alzheimer's: Indicated for moderate to severe alzheimer's dementia, and used best in combination with anticholinergic drugs. Seems to slow memory loss, improve behavior, especially agitation, and maybe very useful in nursing homes, where has been noted to improve tv watching. Actually very safe, but only modestly effective. ...Read more
Namenda (memantine): Yes you do.Get a more detailed answer ›
Allergy: Allergic to NamendaGet a more detailed answer ›
Neurochemistry 101: Persistent activation of central nervous system nmda receptors by the excitatory Amino Acid glutamate has been hypothesized to contribute to the symptomatology of alzheimer’s disease. Namenda (memantine) is postulated to exert its therapeutic effect through its action by blocking nmda receptors. Namenda (memantine) is approved by the fda for the treatment of moderate to severe alzheimer's dementia. ...Read more
For Alzheimer's: Memantine is used to control symptoms of moderate to severe alzheimer's disease, and may help behavior, adl's, and confusion. It is modestly useful and is best employed in combination with anti-cholinergic medicines. ...Read more
Dizziness: The main side-effect (3%) compared to placebo in fda trials was dizziness. However a small percentage of demented patients may have varying symptoms including aggressiveness, apathy, depression. Behavioral changes happen within the first few weeks as a rule but are reversible with discontinuation. ...Read more
Probably not: This is not one of the listed side effects. However, if you began having this problem when you started the medication, contact your doctor and discuss this with him/her. ...Read more
Since I have been of Donezepil I am forgetting more. Does Donezepil make you forget more? Been on Donezepil since 5/14 previous on Namenda (memantine) for 1 month
Donepezil & memory: Because donepezil (aricept, a cholinesterase inhibitor) and Nemenda (memantine, an NMDA receptor antagonist) are both used to treat memory disorders, it is difficult to establish if a patient, who already suffers from a form of dementia is having a side effect, or is experiencing progression of their memory problem. See ur prescribing doc. S/He, who knows your course & history, can determine 4 u! ...Read more
Used for Alzheimer: It's used to treat the symptoms of alzheimer's disease. It works by decreasing abnormal activity in the brain. Can help people with alzheimer's disease to think more clearly and perform daily activities more easily, but it is not a cure and does not stop the progression of the disease. ...Read more
Expired Namenda (memantine): Not advised. Call your doctor for a new prescription. ...Read more
I take Namenda (memantine) 10mg once a day but have not noticed an improvement, just noticed that it has gotten worse. It has been a month, when does it kick in?
Step-by-step: The mfg suggests a weekly step up over a month from once a day 5mg thru twice a day 10mg. So, your dose is only half that. Also, it is intended for Alzheimer's not vascular - so, it might not be the best for you depending on your condition. Your doctor is the best person to discuss this all with. It's follow-up to the prescribing. Best! ...Read more
No: Namenda (memantine) is just delaying the progression of alzheimer's disease. ...Read more
Weeks into taking Namenda (memantine) I started forgetting things, doc switched me to Donezepil and I am now more confused Doc re-prescribed it Should I stop?
Aricept (donepezil) & memory: Ur q hi-lites the complexity of geri psych & importance or working closely with ur doc to determine which symptoms are being caused by which illness. Because depression, when severe enough, can cause memory problems - it's key that ur mood tx remains hi priority. If you also have a memory d/o (like AD), donepezil may b right 4 u. What's most important is that you discuss ANY change in meds w doc! ...Read more
Not usually: Getting off Namenda (memantine) should not result in any effect on weight usually. ...Read more
My dr is giving me namenda (memantine) for OCD, will it lower sex drive as other ocd meds do?, it is usually for old people so I guess there is no way of knowing, since they anyway have no sex
Too strange: Your situation is far too unusual to address. Namenda (memantine) for OCD is unheard of. IT would be wise to stay within more established parameters of treatment. ...Read more
My mom just prescribed Namenda (memantine) for the 1st time for her dementia, the confusion and forgetfulness began about 3-4 months ago. Will this help?
Namenda (memantine) is one of several drugs used for dementia, and is reasonable to use. I assume her doctor did a thorough work up to assess thyroid function, B vitamin deficiencies, depression, other brain dysfunction, or a chemical reaction to other meds she was taking first.
Should this fail, other meds should be tried. You mentioned her age, but it should not be assumed this is just old age. ...Read more
My dr gave me namenda (memantine) to lower glutamate levels, he said there were studies that show it can help for OCD, since glutamate causes excitement, can this med cause me emotional numbness, plz explain, ty?
OFF LABEL USE: There is some anecdotal data on off label use for namenda (memantine) for treatment resistant ocd. Discuss with your doctor your concerns. Especially if you have failed multiple Meds. If you are not satisfied, seek a second opinion. ...Read more