Doctor insights on:
Are You Fertile After A Bone Marrow Transplant
Very likely: Bone marrow transplantation require total body irradiation and/ or high dose chemotherapy prior to the transplant. This will render the vast majority of women and men infertile due to damage to germ cells (eggs and sperm cells). Fertility preservation should be discussed prior to treatment. Options for men sperm freezing or testicular tissue freezing, or women egg/embryo or ovarian tissue freezing. ...Read moreSee 2 more doctor answers
In medicine: a transfer from one body or body part to another of an organ (liver, heart, lung, kidney, pancreas bowel) or tissue (hand, face, hair). The immune system fights foreign invaders (like infections) so it will reject transplants from other people (allotransplants) because they look like infections. So transplants usually require drugs to ...Read more
Failed BMT: Please provide more details. The answer to this is dependent on many factors which you did not provide--what type of transplant was done, who was the donor or was it the patient's own cells, what specifically was the cause of failure (recurrent cancer, bone marrow never grew, loss of the graft). ...Read moreSee 1 more doctor answer
How to become a bone marrow donor? I'm interested in becoming a bone marrow donor, but i don't know anything about what that procedure involves.
Red Cross: Speak to your local red cross representative. They may be able to do testing, or refer to you a hospital where you can be tested. The procedure for harvesting a bone marrow sample is often painful, as you have to pierce the iliac crest in your hip to get to it. This will be anesthetized, but it can still often be painful. ...Read more
Yes you can: depends on many factors though, but the majority can conceive, and should treated as high risk pregnancies, please checkthos link: http://www.motherisk.org/prof/updatesDetail.jsp?content_id=727 ...Read more
How common for person to have consistent fevers from chemo, just before having a bone marrow transplant?
Depends: It depends on the type of chemotherapy you are getting and the type of cancer that is being treated. Although some types of cancers, like leukemias, can cause fevers themselves, it usually isn't a good sign that you are having fevers. Sometimes this is expected but almost always needs a closer look by your doctor. Please call your doctor as soon as possible. Hope this helps. ...Read more
After high dose chemotherapy, is your marrow destroyed, so you would need a bone marrow transplant?
Not really like that: If the person needs high dose chemo to treat underlying acute leukemia or other kind of blood cancer for instance- the bone marrow transplant is aimed to cure the leukemia/blood cancer-not really to treat the destroyed marrow from chemo. Certain chemo however can cause myelodysplastic syndrome which later can transform into leukemia, and transplant-if possible- would be the treatment option. ...Read moreSee 1 more doctor answer
Intense regimen...: Typically bone marrow transplants completely destroy (ablate) your marrow, usually using a combination of intense chemo and radiation. The new marrow is infused by iv, and you must wait in hospital for these cells to repopulate your marrow (engraftment). Possible complications include infection and graft versus host disease (gvhd). You will spend alot of time in hospital and have close follow-up. ...Read more
Treatments: If leukemia returns after a bone marrow or stem cell transplant it can still be treated. The type of therapy will be based on many factors such as the type of leukemia, ongoing medical problems, prior therapies used. In some situations additional infusions of donor immune system cells (dli or donor lymphocyte infusions) can be performed. ...Read more
Be ready : Be ready physically and mentally. Keep your positive attitude. Also, you may want to pack some personal items, including things like books, laptop, music/gadgets, bible etc- things that you can do to kill some time. You would be in the hospital for a few weeks by yourself in an isolated room. You will need to have something to kill your boredom and keep your sanity. Good luck and god bless you. ...Read more
It's complicated.: There are different protoclos but generally it starts with drugs to supress or destroy recipient bone marrow, and drugs to block the immune system so the graft can "take". Blood counts are low, and infections occur, transfusions needed. Once engrafted, worry is graft vs host disease and powerful immunosupressive drugs are given to prevent or treat gvhd. Sites are lung, liver, skin, GI tract. ...Read more
What outcome can I expect from a bone marrow transplant? What is the success rate for bone marrow transplants?
It depends.: The recovery from autologous transplant is much quicker than allogeneic transplant, typically 90 days or so. Recovery from allogeneic stem cell transplant is more difficult to predict, as there are more potential complications, a much slower recovery of immune function that requires avoiding crowds and infection risk for a much longer time. Age and pre-transplant status also play a role. ...Read more
Replace bone marrow: A bmt or stem cell transplant replaces a patient's bone marrow with that of someone else. There has to be treatment to supress the patient's own bone marrow and immune system to allow the new cells to take hold. The stem cells are given IV like a blood transfusion. The first 90 days are high risk, with low blood counts, infections & graft vs host disease the big issues. ...Read more
It is simple: You can register in the national marrow donor program(called nmdp or be the match). Look it up in the internet or you can go to your local hospital blood bank and ask them to register you as a volunteer/potential donor. ...Read more
Could you explain te exact prcess of a bone marrow transplant; harvesting and transplanting processes?
A match for bone marrow transplant? A distant relative needs a bone marrow transplant. How can I find out if i'd be a match?
Short answer: Hla. Human leukocyte antigens (hla) are proteins — or markers — found on most cells in your body. Your immune system uses these markers to recognize which cells belong in your body and which do not. A close hla match between patient and donor is the most important factor in selecting the best bone marrow donor for a patient. ...Read more
This refers to using chemotherapy and/or radiation therapy to treat patients and then replacing their bone marrow cells with their own stem cells (autologous transplant) or a donors stem cells (allogeneic transplant). Bone marrow transplant generally refers to using bone marrow cells but is often used when using stem cells collected ...Read more
Bone marrow is the flexible tissue found in the interior of bones. In humans, red blood cells are produced in the heads of long bones, in a process known as hematopoesis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult weighing 65 kilograms (140 lb), bone marrow accounts for approximately ...Read more
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