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Doctor insights on: Are There Treatment Guidelines For Bone Metastases

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Are there treatment guidelines for bone metastases?

Are there treatment guidelines for bone metastases?

It hard to: Cancer moving to the bone is hard to dicuss in few line, i will provide you with a link could help you.Good luck thank you. ...Read more

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Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more


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What is the latest treatment for small cell carcinoma of the lung with bone metastases?

What is the latest treatment for small cell carcinoma of the lung with bone metastases?

Clinical trial: Clinical trial or standard chemotherapy. Bone mets can be treated with bisphosphonate (zometa) or Denosumab (xgeva). Mri of the brain should evaluate for brain mets. Trials: http://clinicaltrials.Gov/ct2/results?Term=small+cell+lung+cancer&recr=open&no_unk=y standard of care chemotherapy is a 2 drug combination with a "platinum". ...Read more

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How effective is radiation therapy on bone metastases?

How effective is radiation therapy on bone metastases?

Very: Radiation is the treatment of choice for bone mets its very effective palliative therapy for cancer with bone mets. ...Read more

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What can we expect from a stage 4 lung cancer patient with bone metastases- what can be done in case all treatments are ruled out?

Biomarkers in lungCA: For stage 4 non-small cell lung cancer -- specifically adenocarincoma -- i would check the biomarkers alk and egfr. The response rate with oral drugs for those targets is ~80% vs. 20% with chemo. Bone mets can be treated with bisphosphonate (zometa) or Denosumab (xgeva). Palliative care provided early has a survival benefit. Ref: temel et al. Nejm http://www.Nejm.Org/doi/pdf/10.1056/nejmoa1000678. ...Read more

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What does bone metastases cause?

Pain etc: Bony mets can cause bony pain ( depending on the location), fractures, spinal cord compression resulting in significant nerve deficits on extremities/weakness/can develop paralysis etc, suppresion to the blood counts if cancer also involves the bone marrow etc. ...Read more

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Is it true not all bone metastases give you pain?

Is it true not all bone metastases give you pain?

Yes. not always.: Not all bony metastases give you pain- depending on the size and the location. When it gets bigger, pain will manifest and there is significant risk for bone fracture. Therapy for bony metastases wll include- chemotherapy for that particular cancer; palliative radiation to reduce pain/symptoms, some times surgery can be done ( very selected case); and bisphosphonates such as zometa or x-geva. ...Read more

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Help please? I want to know what are illdefined osteolytic lesions in bone metastases?

Help please? I want to know what are illdefined osteolytic lesions in bone metastases?

Bone mets: Bone metastases can cause focal areas of bone loss or destruction, called "osteolytic". If they cause a focal bone response of increased density or sclerosis, they are called "osteoblastic". "Ill-defined" means that the borders of the bone met are not clearly visualized, which may imply a faster growing or more aggressive met. Slow growing or indolent lesions tend to develop well defined margin ...Read more

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What's the life span of bone metastases ?

It depends: There are 2 factors that are important. One is the type of cancer and the second is the response to treatment. For metastatic breast or prostate cancer to bone that responds to hormone treatment it could be years. For melanoma that is not responsive it could be a few months. ...Read more

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What are the odds of survival for patients with bone metastases?

Hard to day.: Depends on the tumor type and aggressiveness. Some tumors may respond to chemo and radiation for years. Others may be rapidly progressive and spread to other organs like liver and brain. A, "cure" is not in the cards. ...Read more

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How good is radiation on bone metastases?

How good is radiation on bone metastases?

Depends: Depends on the primary tumor, you have to trust your oncologist on the right path. ...Read more

Metastasis (Definition)

A cancer begins in an organ (say the breast). If it gets into the blood stream or the lymphatic stream the cells can travel to other parts of the body where, in the right environment, they may settle and grow. This development of tumor growth far away from the original site ...Read more