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Doctor insights on: Are There Long Term Affects To Taking Azathioprine For A Child

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Are there long term affects to taking azathioprine for a child?

Are there long term affects to taking azathioprine for a child?

Genetic mutation: Azathioprine ( Imuran (azathioprine) ) is apurine antimetabolite, immnosupressive agent used after transplantation, if it is the case it is safer than other drugs. It is also used for other diseases like inflamatory bowel dis, rheumatoid arthritis etc, then alternative medication to be used. It can not be used in pregnancy, it has mutagnic potential , potential to develop maligencies, . ...Read more

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Dr. Jeremy Adler
465 doctors shared insights

Azathioprine (Definition)

Azathioprine is a non-steroidal anti-inflammatory which is a ...Read more


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Can there be a causal relationship between long-term use of an immunosuppressant (e.g. Azathioprine) and lymphoid hyperplasia?

Can there be a causal relationship between long-term use of an immunosuppressant (e.g. Azathioprine) and lymphoid hyperplasia?

Yes: There is literature to support increased risk of B-cell lymphoma as well. Should be appropriately worked up if lymph node enlargement is identified. ...Read more

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If you take imuran (azathioprine) for lupus will you ever be able to get pregnant with a child?

If you take imuran (azathioprine) for lupus will you ever be able to get pregnant with a child?

Yes/no: Imuran (azathioprine) can be harmful to the fetus...So it has to be stopped during early pregnancy. ...Usually the first 2-3 months(first trimester), which is the time of most risk to the baby). So it requires careful planning and timing so that you can be off this medication for a short period and then may be able to resume during the 2nd and 3rd trimester with reasonable safety. ...Read more

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36 yo female with right ear pain for 2 days (no fever, drainage or other symptoms). History of ear infections as adult and child. I take azathioprine for crohn's. Should i go to doctor or wait?

36 yo female with right ear pain for 2 days (no fever, drainage or other symptoms). History of ear infections as adult and child. I take azathioprine for crohn's. Should i go to doctor or wait?

Any hearing loss: The first question i ask a patient with ear ache (otalgia) is if there is any hearing loss associated with pain. If there is no hearing loss and particularly if the pain is in front of the ear, i would be thinking tmd. This could be joint disease, muscle spasm or referred pain to the side of the face (ear) from dental disease as the other reviewer suggested. ...Read more

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I have been on imuran (azathioprine) 50 mg for about 2 months, how long do people usually stay on this medication, because it has many side effects and I am worried?

I have been on imuran (azathioprine) 50 mg for about 2 months, how long do people usually stay on this medication, because it has many side effects and I am worried?

Crohn's dosease: Depends on the relief of symptoms called remission. The remission time is different in person to person. Looks like you have flare or relapse because you are taking other meds as well. Your doctor would evaluate the status of crohn's disease time to time and adjust the treatment accordingly. ...Read more

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Was on imuran (azathioprine) for 3 months. I stopped it 2 weeks ago. It caused severe fatigue and i still am always tired. How long till it gets back to normal?

Depends on illness: This depends on what the rest of your illness is. Either it should be pretty much out of your system by now. You may want to check with your physician to see what other issues are going on that might explain your symptoms ...Read more

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How long does it take for myasthenia gravis symptoms to go away on medications like prednisolone,azathioprine?

Working meds: It depends on the half life of the medication and your own body's ability to metabolize the medication and utilize it for its purpose. Your pharmacist can be very helpful with this tyoe of information as well as the package insert. Well wishes and do not delay an office visit if symptoms show no improvement. ...Read more

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How long does it take for blood counts and liver enzymes to return back to normal after stopping imuran (azathioprine) ?? And how long will side effects reverse ?

Within 1-3 months: Imuran (azathioprine) is a drug used to suppress the immune system in many diseases. Monitoring liver function tests is used to detect hepatotoxicity, generally defined as elevated AST/ALT greater than twice normal. Dose reduction or split dosing, or use of allopurinol may minimize hepatoxicity, but the vast majority of patients will reverse the liver injury within 1-3 months after discontinuation of Imuran (azathioprine) ...Read more

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How long does it take for imuran and plaquenil (hydroxychloroquine) to clear up from your system after taking them for 1 month?

Half life: Hi, imuran has a very short half-life about 5-6 hours therefore it clears from body so quickly but Plaquenil (hydroxychloroquine) half-life is 30-50 days so it could stay in the body for long time. ...Read more

Dr. Jeremy Adler
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Imuran (Definition)

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Dr. Jan Lei Iwata
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