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Doctor insights on: Are There Any Long Term Dangers To Taking Enbrel

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Dr. Michio Abe Dr. Abe
Internal Medicine
22 years in practice
George Washington University Medical School
1

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Are there any long term dangers to taking enbrel (etanercept)?

Are there any long term dangers to taking enbrel (etanercept)?

Enbrel (etanercept): There are many potential dangers to taking enbrel, (etanercept) which should be discussed with your physician. Enbrel (etanercept) suppresses your immune system, which can increase the risk of many forms of infections, including upper respiratory infections, tb, hepatitis b reactivation, and opportunistic fungal infections. Immune suppression can also increase the risk of developing cancer such as lymphoma and leukemia.

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Dr. Robert Lowe
124 Doctors shared insights

Etanercept (Definition)

Etanercept is an immune system suppressor which is a kind of ...Read more


Dr. Ronald Krauser Dr. Krauser
Internal Medicine - Rheumatology
48 years in practice
Wake Forest University School of Medicine
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Since enbrel (etanercept) has lots of long term side effect why its not possible to change the med to other med with less side effect when ur RA is under control?

Since enbrel (etanercept) has lots of long term side effect why its not possible to change the med to other med with less side effect when ur RA is under control?

See details: Actually Enbrel (etanercept) is a reasonably safe drug over the long term. Stopping Enbrel (etanercept) will end its effectiveness and it is highly likely the arthritis will flare. If it wasn't controlled on milder meds before Enbrel (etanercept) it is highly likely it won't be controlled this time either. You can always try it if your rheumatologist agrees. I reserve the right to tell you 'i told you so.'.

Dr. Ronald Krauser Dr. Krauser
Internal Medicine - Rheumatology
48 years in practice
Wake Forest University School of Medicine
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Recently diagnosed with psoriatic arthritis & prescribed enbrel (etanercept). How effective, in the long term, are these injections? Any downsides? Thank you!

Recently diagnosed with psoriatic arthritis & prescribed enbrel (etanercept). How effective, in the long term, are these injections? Any downsides? Thank you!

Extremely effective: Tnf agents are extremely effective in the treatment of psoriatic arthritis. It is surprising that the side effects were not reviewed with you prior to starting the med. The major risk is infection with other possible side effects being reduced blood counts, liver inflammation, neurologic disorders and a possible increased risk of lymphoma.

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Dr. John Goldman Dr. Goldman
Internal Medicine - Rheumatology
51 years in practice
University of Cincinnati College of Medicine
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How long still I see results with enbrel (etanercept)?

How long still I see results with enbrel (etanercept)?

Few days to 3-4 week: Some people have a dramatic response, while others may take up to 3 months or more. Depending on how your joints are doing will aid your physician in telling about your response. It also depends on your diagnosis of the reason you are taking it: ra, psoriasis or psoriatic arthritis, ankylosing spondylitis or jia.

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Dr. Howard Feinberg Dr. Feinberg
Internal Medicine - Rheumatology
33 years in practice
Western University of Health Sciences College of Osteopathic Medicine of the Pacific
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7yr old on enbrel (etanercept) been having injection site reactions each time bigger than last. Last time 3.5inches long. At what point should she stop taking it?

7yr old on enbrel (etanercept) been having injection site reactions each time bigger than last. Last time 3.5inches long. At what point should she stop taking it?

Not dangerous: First, rest assured, the injection site reaction is not dangerous. There are several options: 1) try the prefilled syringe instead of injector. We see less redness and pain with this form. 2) ice the area immediately after the shot. This will decrease the reaction. 3) switch to alternate medication such as Humira (adalimumab). You should voice your concerns to your doc and discuss options

Dr. Oscar Novick Dr. Novick
Pediatrics
54 years in practice
University of Bern Faculty of Medicine
6
Dr. Ronald Krauser Dr. Krauser
Internal Medicine - Rheumatology
48 years in practice
Wake Forest University School of Medicine
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Why does it take so long for certain insurances to approve drugs like Enbrel (etanercept)? Do they enjoy making patients suffer while we're at their mercy?

Why does it take so long for certain insurances to approve drugs like Enbrel (etanercept)? Do they enjoy making patients suffer while we're at their mercy?

See details: You have asked a very important question that continually frustrates patients and doctors. My cynical explanation is that it is always about money.

Dr. Robert Lowe Dr. Lowe
Pediatric Rheumatology
13 years in practice
University of Washington School of Medicine
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I started enbrel (etanercept) for as last may and had great results, but it took three months. I had to stop in jan. For two surgeries. Going back on now. Is it likely to take as long to be close to pain free?

I started enbrel (etanercept) for as last may and had great results, but it took three months. I had to stop in jan. For two surgeries. Going back on now. Is it likely to take as long to be close to pain free?

Depends: It likely depends how bad of a flare you had while off of the enbrel (etanercept).A more severe flare may take a few weeks longer on Enbrel (etanercept) before you are pain-free compared to if you have a mild flare if you are only taking it weekly, ask your rheumatologist if he/she recommends increasing frequency of dosing to twice per week for the first 3-4 doses to get you feeling better sooner. Consider nsaids for 2-3wks.

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Dr. Ronald Krauser Dr. Krauser
Internal Medicine - Rheumatology
48 years in practice
Wake Forest University School of Medicine
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How long will it take for scalp psoriasis to go away after the initiation of enbrel (etanercept) 50 mg/week?

How long will it take for scalp psoriasis to go away after the initiation of enbrel (etanercept) 50 mg/week?

It varies.: Enbrel (etanercept) and similar biologic medications are extremely effective therapies for psoriasis. The length of time needed to totally resolve the rash depends on the severity of the skin involvement. 3-4 months is a reasonable time.

Dr. Ronald Krauser Dr. Krauser
Internal Medicine - Rheumatology
48 years in practice
Wake Forest University School of Medicine
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How long before methotrexate works for jra? How long do u need to be on it before adding another med like enbrel (etanercept)?

How long before methotrexate works for jra? How long do u need to be on it before adding another med like enbrel (etanercept)?

See details: If you have a good response to Methotrexate it can remain effective indefinitely. I will add a tnf like Enbrel (etanercept) if Methotrexate is not effective after 3-4 months at a dose of at least 20 mg weekly.

Dr. Pierre Moeser Dr. Moeser
Internal Medicine - Rheumatology
years in practice
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Is there a waiting period between changing from enbrel (etanercept) to humira? If so, how long? Then how long before humira begins to work?

Is there a waiting period between changing from enbrel (etanercept) to humira? If so, how long? Then how long before humira begins to work?

One week: I would start Humira one week after your last Enbrel (etanercept) injection. There is no hard and fast rule. I have seen Humira work as quickly as within two weeks and as long as three months. These medications should be given for at least three months before switching. Good luck.

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Dr. Larry Lutwick Dr. Lutwick
Internal Medicine - Infectious Disease
45 years in practice
George Washington University Medical School
12
Dr. Bennett Machanic Dr. Machanic
Neurology
48 years in practice
Johns Hopkins University School of Medicine
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I have MS and can no longer use enbrel (etanercept) which worked great for my psoriasis....I started methotrexate 3 weeks ago and no real change yet, any ideas?

I have MS and can no longer use enbrel (etanercept) which worked great for my psoriasis....I started methotrexate 3 weeks ago and no real change yet, any ideas?

Suggestion: You possess a complex problem which afflicts several patients; i.e., two automimmune disorders. This creates a need to have very coordinated care from both a neurologist and a dermatologist, and you are advised to get a consult or two from a local medical school. The Methotrexate may yet work, as could take a few more weeks, but you may want to modify your ms medicine if needed.

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Dr. Ronald Krauser Dr. Krauser
Internal Medicine - Rheumatology
48 years in practice
Wake Forest University School of Medicine
15
Dr. William Lages Dr. Lages
Internal Medicine - Rheumatology
64 years in practice
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My daughter on methotrexate and enbrel (etanercept) is it ok for her to be around my mom who has MRSA on your arm pit? They packed it today how long to wait?

My daughter on methotrexate and enbrel (etanercept) is it ok for her to be around my mom who has MRSA on your arm pit? They packed it today how long to wait?

Only with cautions: Your daughter is on immunosuppression and it is unwise to be near anyone with active contagious infection. MRSA is a hazardous bacteria and she should not be near or touch anything your mother has come in contact with until your mother`s doctor says she is cleared.

Dr. Al Hegab Dr. Hegab
Internal Medicine - Allergy & Immunology
36 years in practice
Ain Shams University Faculty of Medicine
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My mom has been using Enbrel and have diagnosed with Parkinson. Is that kind of Rheumatoid Arthritis biologic treatment dangerous for Parkinson or not?

My mom has been using Enbrel and have diagnosed with Parkinson. Is that kind of Rheumatoid Arthritis biologic treatment dangerous for Parkinson or not?

Enbrel: And its use in the presence of a neurologic disease as Parkinson or in elderly patients? A question of risk/benefit ratio, some biologicals need to be used with caution above age 65, enbrel is one of them, also in patients with demyelinating disease, Parkinson isn't, so this delicate and complex question need to be answered in a clinical context, the best to do so is the treating doctor/team,

Dr. Heidi Fowler Dr. Fowler
Psychiatry
21 years in practice
Uniformed Services University of the Health Sciences F. Edward Hebert School of Medicine
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Could I drink alcohol while taking enbrel (etanercept)?

Could I drink alcohol while taking enbrel (etanercept)?

No interactions: Were noted using the Drugs. Com drug interaction checker. But, that doesn't mean that an interaction couldn't occur.

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Dr. PHILIP WALLER Dr. WALLER
Internal Medicine - Rheumatology
29 years in practice
Loyola University Chicago Stritch School of Medicine
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To start taking enbrel (etanercept) --any bad side effects?

To start taking enbrel (etanercept) --any bad side effects?

Potentially: Enbrel (etanercept) is in a class of drugs that can treat diseases such as ra. But it does have potential side effects such as serious infections. It can reacitivate TB so your doctor must do appropriate tests before you start the medication. The biologics can cause an increase in skin cancers. Also headaches, skin rashes, and local injection reactions can occur. Talk to your doctor, read about the med.

Dr. Robert Jackson Dr. Jackson
Dermatology
39 years in practice
Meharry Medical College School of Medicine
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Dr. Robert Lowe
143 Doctors shared insights

Enbrel (Definition)

Enbrel is an immune system suppressor which is a kind of ...Read more