Doctor insights on:
Are Obese People Resistant To Leptin
Yes: Although leptin is a circulating signal that reduces appetite, obese individuals generally exhibit an unusually high circulating concentration of leptin. These people are said to be resistant to the effects of leptin, in much the same way that people with type 2 diabetes are resistant to the effects of insulin. ...Read moreSee 1 more doctor answer
Yes: There are many hormones that help modulate energy balance in the body. Leptin is one hormone (of many) that makes you feel full. Ghrelin is one hormone (of many) that makes you feel hungry. There are other hormones and neurotransmitters that keep the system redundant and hard to modify. ...Read more
Can you tell me about animals with a leptin deficiency or a defect in leptin receptors exhibit hyperphagia (overeating) and extreme obesity. Why?
Perindopril reduces leptin levels in obese patients.Will it increase weight?Are there any medicines 2 increase Amylin&leptin 4 weight loss?Plz help
I am a narcoleptic with cataplexy. Does that mean I am leptin resistant and need to take leptin supplements or go on a leptin diet?
Fat controlling: Hormone , or some times called 'starvation hormone ' controls its deposition , depletion , ( putting fat on or taking it off ) . There is no convincing scientific proof by exogenous intake , ( food or pills ) it will do the same , only one who gets benefit is the one who makes and sells.. Only proven way to loose weight , limiting intake , spending more time in gym , no time on couch ...Read more
It probably doesn't: All diets are the same , low calorie, low carb and some supplements that should suppress appetite, like leptin. The problem is these experiments are conducted in mice and humans do not respond the same way to these meds. Very hard to lose weight but cutting calories and moving more can help. ...Read more
Not so simple: Leptin does help regulate weight by curbing appetite and the amount of leptin you make is directly related to how much fat you have stored, However, overweight people seem to become resistant to the appetite effects of leptin and continue to eat more than they need even with high leptin levels. There is no way to activate your leptin - it is there but not working to help you lose weight ...Read more
Hunger decreases: Leptin is a neuro-transmitter produced by fat cells that tell the brains that you need calories (starvation indicator), When it falls you get the sensation of hunger. When it rises you become satiated. This may help: http://www.webmd.com/diet/obesity/the-facts-on-leptin-faq ...Read more
May cause weightgain: Recently, a study was published that may possibly exhibit a link between fruit consumption and weight gain. The study determined that high consumption of fructose may well be a cause of leptin resistance. By eating fruit, you can help the natural occurring leptin to help increase your body's metabolism function - high leptin is correlated with leptin resistance. ...Read moreSee 1 more doctor answer
Evidence suggests ..: Leptin signals the brain that the body has had enough to eat, producing a feeling of satiety. A very small group of humans possesses homozygous mutations for the leptin gene, leading to a constant desire for food and resulting in severe obesity. Over consumption of carbohydrates without sufficient exercise can lead to Insulin resistance and blood sugar elevation which characterize diabetes. ...Read moreSee 1 more doctor answer