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Doctor insights on: Are Myelofibrosis And Multiple Myeloma Are Related To Each Other

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Dr. Cornelius O'leary jr
118 doctors shared insights

Kahler Disease (Definition)

I had not heard of "kahler's disease" until seeing multiple questions on healthtap. It is multiple myeloma (mm). "multiple" is from the often seen "multiple" bone lesions (especially in advanced disease). Mm is a cancer of plasma cells [highly specialized b white blood cells (lymphocytes)] that produce antibodies. Sx are crab: hypercalcemia, renal insufficency, anemia, ...Read more


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How will my doctor know if I have multiple myeloma? 

Labs, xrays: There are a series of blood and urine tests that will give the doctor a good idea if you have the disease. These are usually followed by x-rays looking for tell-tale signs of myeloma and a bone marrow test which would identify the cancer cells themselves. ...Read more

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Are myelofibrosis and multiple myeloma are related to each other?

No: They are totally different diseases. Myeloma is a malignancy that develops in a type of blood cell called a plasma cell. Myelofibrosis is a disease of the bone marrow microenvironment. ...Read more

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Is it necessary to take dexa along with Velcade (bortezomib) same day for multiple myeloma patient of 80 yrs as acute diarrhea is encountered after every dose?

Is it necessary to take dexa  along with Velcade (bortezomib) same day for multiple myeloma patient of 80 yrs as acute diarrhea is encountered after every dose?

See below: Velcade may produce diarrhea, but DEX usually not. Velcade and DEX have been given same day only for the convenience, and I see no reason to try to give them on separate days. Alternatively, one can reduce the dose of Velcade or try anti-diarrhea agent prophylactively, such as imodium (loperamide). Diarrhea needs to be treated with antidiarrhea agents and electrolytes monitoring. ...Read more

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Pl suggest any alternative remedy/ies for multiple myeloma I am 48 yer old and no m band seen at this moment after 6 months of chemo?

Pl suggest any alternative remedy/ies for multiple myeloma  I am 48 yer old and  no m band seen at this moment after 6 months of chemo?

Homeopathy, herbs ;: There are no proven alternatives for multiple myeloma but that does not mean they may not help; but i would continue standard treatments too. A healthy diet, tonifying herbs, reducing body burden of heavy metals ; other environmental toxins, stress reduction ; working to clear unresolved anger/grief etc. Can only help. I also advise classical homeopathy with a good homeopath. See comments for more:. ...Read more

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How common is multiple myeloma?

How common is multiple myeloma?

Uncommon: Approximately 1% of all cancers and slightly more than 10 % of blood cancers in the United States. ...Read more

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What other tests for multiple myeloma?

What other tests for multiple myeloma?

Blood/Urine/Imaging: Usually workup involves blood and urine tests (spep / upep - serum and urine protein electrophoresis). The preferred initial imaging study is the skeletal survey (x-ray of multiple sites of the body including skull, axial skeleton, and proximal long bones). Bony lesions are usually lytic. ...Read more

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Dr. Liawaty Ho
737 doctors shared insights

Multiple Myeloma (Definition)

Multiple myeloma is a cancer of the plasma cells, which are responsible for producing antibodies for your body. Symptoms include kidney insufficiency, anemia, bone ...Read more