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Doctor insights on: Are Hb's Levels Elevated With Beta Thalassemia Trait

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Are hb s levels elevated with beta thalassemia trait?

Are hb s levels elevated with beta thalassemia trait?

No: With beta thalassemia trait alone, no hemoglobin s should be detected. If hemoglobin s is being detected in addition to beta thalassemia trait then the patient has a form of sickle cell beta thalassemia disease. ...Read more

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Dr. Craig MacArthur
67 doctors shared insights

Beta Thalassemia (Definition)

A genetic blood disorder that limits a person's ability to produce hemoglobin, thus leading to anemia due to an inadequate amount ...Read more


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What is d trait in hb electrophoresis report?

What is d trait in hb electrophoresis report?

A variant of normal: Hemoglobin d is a variant of normal hemoglobin. Is in unlikely to cause any significant problems but may be associated with mild anemia. You should discuss specifics about this with your physician. ...Read more

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My 6 yo had appt w/ hematology. Results show elevated ldh, elevated retic and increased hgb F. Is this consistent with beta thalassemia trait?

My 6 yo had appt w/ hematology. Results show elevated ldh, elevated retic and increased hgb F. Is this consistent with beta thalassemia trait?

Other ideas: There are a variety of mild hemoglobinopathies that might be a better fit. I am glad Junior is going to get his workup so he can make informed choices as an adult. Best wishes. ...Read more

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Some adults with sickle cell anemia have high levels of fetal hemoglobin. Any reason for this?

Some adults with sickle cell anemia have high levels of fetal hemoglobin. Any reason for this?

Epigenetics and drug: We know that sickle cell patients that have increased Hemoglobin F typically have less sickle cell complications. This is the basis for using Hydroxyurea in sickle cell patients. Some individuals have elevated Hemoglobin F levels due to differences in the genetic region of the beta and gamma globin genes that prevent the normal shutting-off of the gamma globin gene. This leads to increased HGB f. ...Read more

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Why anemia caused when hb is "hb e/beta thallassemia?

Why anemia caused when hb is "hb e/beta thallassemia?

Need more info.: The pattern of your blood counts over the years would be helpful. Many asian populations have hemoglobin e. Beta thal trait is also frequently seen. You need to see your hematologist to clarify what is going on and any potential treatments. Good luck. ...Read more

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What are normal beta 2 microglobulin levels in a healthy individual?

What are normal beta 2 microglobulin levels in a healthy individual?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, You may consult this site for information on this topic. http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/9234 ...Read more

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My baby have hb e/beta thalassemia? Is it sickle cell disease?

My baby have hb e/beta thalassemia? Is it sickle cell disease?

No: It is not sickle cell disease. It is a "hemoglobinopathy" or genetic disorder of hemoglobin...And it can cause anemia. Sickle cell has malformed red blood cells that become "sickle" shaped and can get stuck in organs and vessels and cause pain. E/beta thalassemia is different. ...Read more

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Can a person wtih alpha thalassemia trait donate blood?

Can a person wtih alpha thalassemia trait donate blood?

Maybe: A person with Alpha thalassemia trait may be not anemic or mildly anemic. If he is not anemic, he can be a blood donor. However, since he has a more difficult time making hemoglobin (to make new red blood cells), he may not wish to be a blood donor. ...Read more

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Is it normal to have ice cravings with beta thalassemia anemia?

Maybe: Ice cravings has been reported as a symptom of iron deficiency anemia. Some people believe ice cravings also occur in other forms of anemia, such as thalassemia anemias. It is not known how many non-anemic persons have ice cravings, so it is unknown how likely it would be for a ice cravings to occur coincidentally with an anemia but not due to the anemia. ...Read more

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Is hb e beta thalassemia cureble? Is it a trait or disease?

Genetic disorder: http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3237252/ "the disorder is characterized by marked clinical variability, ranging from a mild and asymptomatic anaemia to a life-threatening disorder requiring transfusions from infancy. "...."careful tailoring of treatment is required for each patient, and that therapeutic approaches should be re-assessed over-time." not curable..Look at website-. ...Read more

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Is beta thalassemia major andd hb e/beta thalassemia same?

Not the same.: Hemoglobin e is found in the asian population frequently and may be seen with thal trait. Thal major is a serious problem requiring much intervention, including transfusions and frequently splenectomy. Your doctor should be your guiding you. Pregnancy needs to be discussed with your doctor. ...Read more

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Do beta thalassemia and sickle cell anemia always reduce life expectancy?

Do beta thalassemia and sickle cell anemia always reduce life expectancy?

Not if just 1 trait: Having either beta thalassemia trait or sickle cell trait is a mild condition and should not cause symptoms to the point of making a person frequently ill nor shortening life expectancy. Having beta thalassemia major or sickle cell disease, or both sickle cell trait and beta thalassemia trait, usually causes severe enough chronic disease symptoms to shorten lifespan an uncertain amount. ...Read more

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How to differentiate between alpha thalassaemia trait and hb h disease without a genetic test?

How to differentiate between alpha thalassaemia trait and hb h disease without a genetic test?

Electrophoresis, but: Levels of hemoglobin h and hemoglobin barts should make the distinction straightforward though there may be modifying genes that could make interpretation. The real question is the implications in planning your family and for this perhaps you would like to have genetic testing done. Any hematologist would probably enjoy helping you out. Good luck. ...Read more

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Can a female with Hb H disease marry someone with beta thalassemia trait? What are the possible results in terms of genetics percentages?

Sure: Anybody can marry anybody. Since HgbH disease involves the alpha genes and beta thal minor involves the beta genes, I would not be concerned. However, you might do well to be certain that neither partner carries the other person's trait as well masked by what's already diagnosed. Sit down with a competent clinical geneticist. ...Read more

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Can a normal & healthy person may marry with e beta thalassemia , safely?????

Can a normal & healthy person may marry with e beta thalassemia , safely?????

Yes: If you do not carry the gene in any way, any children will be carriers. HbgE/beta thalassemia is a disease that can be mild or severe. The best way to ease your mind is to seek genetic counseling. All the best. ...Read more

Dr. Michael Engel
272 doctors shared insights

Thalassemia (Definition)

An inherited condition characterized by severe anemia (a deficiency of red blood cells), ...Read more