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Doctor insights on: Are Certain Ethnic Groups At Higher Risk Of Osteogenesis Imperfecta

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Are certain ethnic groups at higher risk of osteogenesis imperfecta?

Are certain ethnic groups at higher risk of osteogenesis imperfecta?

In general, No....: .... But certain very small ethnic groups in africa and canada have been observed to suffer an increased incidence. ...Read more

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Dr. Mark Ingerman
95 doctors shared insights

Osteogenesis Imperfecta (Definition)

Osteogenesis imperfecta is a condition causing extremely fragile bones. Osteogenesis imperfecta (OI) is a congenital disease, meaning it is present at birth. It is frequently caused by defect in the gene that produces type 1 collagen, an important building block of bone. There are many different defects that can affect this gene. The severity of OI depends on ...Read more


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What can be done for people with osteogenesis imperfecta?

What can be done for people with osteogenesis imperfecta?

Medical follow up: Medical optimization and surgical stabilization of bones to optimize mobiligy. ...Read more

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Can you tell me about osteogenesis imperfecta inheritance patterns?

Can you tell me about osteogenesis imperfecta inheritance patterns?

Autosomal dominant: Osteogenesis impecta (OI) is transmitted in autosomal dominant fashion. Rare cases of OI, type II B & type II C, are transmitted in autosomal recessive inheritance. ...Read more

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Please tell me can I have osteogenesis imperfecta type 1? How to tell?

Please tell me can I have osteogenesis imperfecta type 1? How to tell?

Genetic testing : Osteogenesis I, can be evaluated and effectively ruled in or out by a geneticist. Physical exam finding, family history, and genetic testing can all be helpful. ...Read more

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What does the karyotype of a person who has osteogenesis imperfecta look like?

What does the karyotype of a person who has osteogenesis imperfecta look like?

Like everyone elses: it is a group of at least 8 genetic disorders. allthough it's genetic: 1) 35% didn't have it in their families (spontaneous mutation?) 2) it is dominant... one good gene one bad gene 3) it is the GENE... sub microscopic change in a handful of atoms in DNA.. NOT the chromosome. ...Read more

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Can osteogenesis imperfecta be curable?

Can osteogenesis imperfecta be curable?

No: osteogenesis imperfecta is not curable. There five types and they vary is severity. They can be treated with medication and allow patient to live with the disease. ...Read more

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Is there a cure for osteogenesis imperfecta?

Is there a cure for osteogenesis imperfecta?

A genetic disorder: Osteogenesis imperfecta is a group of disorders that cause bone fragility due to an error in the genetic code for type i collagen. All tissues that are composed of type i collagen are affected. There are many subtypes ranging in severity and associated comorbidities, but all include fragile bones. There is no cure yet. ...Read more

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Is osteogenesis imperfecta a curable disease?

Is osteogenesis imperfecta a curable disease?

No: It is an inherited connective tissue disease that produces "brittle bones" that results in non-traumatic fractures. It ranges from mild to lethal. There is no cure. Genetic counseling is indicated for the families. ...Read more

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Is osteogenesis imperfecta a chronic disease?

Yes: It exists from conception until death, so it qualifies as chronic.Some are symptomatic at birth and some not until much older. ...Read more

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Dr. Linda DiMeglio
70 doctors shared insights

Brittle Bone Disease (Definition)

Osteogenesis imperfecta is a condition causing extremely fragile bones. Osteogenesis imperfecta (OI) is a congenital disease, meaning it is present at birth. It is frequently caused by defect in the gene that produces type 1 collagen, an important building block of bone. There are many different defects that can affect this gene. The severity of OI depends on ...Read more